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Name |
Topotecan hydrochloride |
EINECS | 601-607-9 |
CAS No. | 119413-54-6 | Density | 1.49 g/cm3 |
PSA | 104.89000 | LogP | 2.64880 |
Solubility | N/A | Melting Point |
213-218 °C |
Formula | C23H23N3O5.HCl | Boiling Point | 782.9 °C at 760 mmHg |
Molecular Weight | 457.914 | Flash Point | 427.3 °C |
Transport Information | N/A | Appearance | White Crystalline Solid |
Safety | 26-36/37/39-45 | Risk Codes | 25-36/37/38-46 |
Molecular Structure | Hazard Symbols | T | |
Synonyms |
Topotecan HCl;Hycamtin;NSC 609669;Nogitecan hydrochloride;SKF 104864A;SKFS 104864A; |
Article Data | 10 |
The Molecular formula of Topotecan HCl (119413-54-6): C23H24ClN3O5
The Molecular Weight of Topotecan HCl (119413-54-6): 457.91
Molecular Structure :
Melting point: 213-218 °C
Index of Refraction: 1.733
Surface Tension: 82.8 dyne/cm
Density: 1.49 g/cm3
Flash Point: 427.3 °C
Enthalpy of Vaporization: 119.49 kJ/mol
Boiling Point: 782.9 °C at 760 mmHg
Vapour Pressure: 8.13E-26 mmHg at 25 °C
Appearance of Topotecan HCl (119413-54-6): White Crystalline Solid
Topotecan HCl (119413-54-6) is naturally occurring amino acid.It is the precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme.And it is antineoplastic (photosensitizer),especially a DNA topoisomerase I inhibitor,just like semisynthetic analog of Camptothecin.
The Hazard Codes of Topotecan HCl (119413-54-6) : T
The Risk Statements information of Topotecan HCl (119413-54-6): 25-36/37/38-46
25: Toxic if swallowed
46: May cause heritable genetic damage
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of Topotecan HCl (119413-54-6): 26-36/37/39-45
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
Topotecan HCl (119413-54-6),also called topotecan monohydrochloride;topetecan hydrochloride;5-piperazin-1-yl-benzofuran-2-carboxylic acid ethyl ester,is white crystalline solid.