- Triphenylphosphine
- Triphenylphosphine hydrobromide
- Triphenylphosphine oxide
- Triphenylphosphine sulfide
- Triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt
- 791-29-7Benzene,1,1',1''-(methylsilylidyne)tris-
- 791-31-1Silanol,1,1,1-triphenyl-
- 79135-18-5Iron(1+), bis(1-(5-((3-(4,5-dihydro-4-((2-hydroxy-4-nitrophenyl)azo)-3-methyl-5-oxo-1H-pyrazol-1-yl)phenyl)azo)-1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinyl)pyridiniumato(2-))-, salt with 2-hydroxypropanoic acid (1:1), bis(2-hydroxypropanoate) (salt)
- 79135-21-0Iron(1+), bis(1-(5-((3-(4-((5-(aminosulfonyl)-2-hydroxyphenyl)azo)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)phenyl)azo)-1-(3-(dimethylamino)propyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinyl)pyridiniumato(2-))-, salt with 2-hydroxypropanoic acid (1:1), bis(2-hydroxypropanoate) (salt)
- 791-35-5Clofedano
- 79135-89-02H-1-Benzopyran-2-one,7,7'-(1,2-ethenediyl)bis[4-methyl-
- 79135-90-3Benzoic acid,3,3',3''-(1,3,5-triazine-2,4,6-triyltriimino)tris[2-hydroxy-5-sulfo-, sodiumsalt (1:3)
- 79-14-1Glycolic acid
- 79-15-2Acetamide, N-bromo-
Hot Products
- 79173-09-4teferrol
- 79186-57-5Hexanoic acid, 2-ethyl-4-(hydroxymethyl)-3-propyl-
- 79230-20-9Borate(1-), tetrakis[3,5-bis(trifluoromethyl)phenyl]-
- 79-27-61,1,2,2-Tetrabromoethane
- 792946-70-4Ethyl 3-amino-4-(4-benzoylpiperazin-1-yl)benzoate
- 79295-18-4(Z)-2-(4-chlorophenoxy)-N'-hydroxyacetimidamide
- 79307-93-0Azelastine hydrochloride
- 79329-75-26-Ethyl-1,2,4,5-tetrazin-3-amine
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Triphenylphosphine oxide |
EINECS | 212-338-8 |
| CAS No. | 791-28-6 | Density | 1.17g/cm3 |
| PSA | 26.88000 | LogP | 3.32600 |
| Solubility | slightly soluble in water | Melting Point |
154-158 °C |
| Formula | C18H15OP | Boiling Point | 462.9 °C at 760 mmHg |
| Molecular Weight | 278.29 | Flash Point | 233.8 °C |
| Transport Information | N/A | Appearance | White solid |
| Safety | 26-61-36 | Risk Codes | 22-36/37/38-52/53 |
| Molecular Structure |
|
Hazard Symbols |
 Xn,  Xi
|
| Synonyms |
phosphorane, triphenyl-, oxide;diphenylphosphorylbenzene;TPPO;Triphenyl phosphorus oxide;Phosphine oxide, triphenyl-; |
Article Data | 1217 |
Triphenylphosphine oxide Synthetic route
| Conditions | Yield |
|---|---|
| With CuO2H In acetonitrile at 70℃; for 6h; | 100% |
| With CuO2H In acetonitrile at 70℃; for 6h; | 100% |
| With periodate form of Amberlyst A26 In chloroform at 25℃; for 2h; | 100% |
| Conditions | Yield |
|---|---|
| With pyridine; trifluoroacetic anhydride for 2h; | 100% |
| With hexyl sulfide; oxygen In methanol; chloroform for 0.5h; Irradiation; | 100% |
| With hexyl sulfide In methanol; chloroform for 1h; Product distribution; Irradiation; other reagents; | 100% |
| Conditions | Yield |
|---|---|
| With oxygen; methylene blue In dichloromethane at -78℃; for 0.0833333h; Irradiation; other reagent; | A 100% B n/a |
| With oxygen; methylene blue In dichloromethane Quantum yield; Irradiation; |
| Conditions | Yield |
|---|---|
| With bromonitromethane In benzene | A 100% B 88% |
| With bromonitromethane In benzene for 12h; Yield given. Yields of byproduct given; |
| Conditions | Yield |
|---|---|
| With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 20h; Mechanism; other thiophosphoramides are also investigated; | 100% |
| With 3,3-dimethyldioxirane In dichloromethane; acetone for 0.0833333h; Ambient temperature; | 100% |
| With pyridine; trifluoroacetic anhydride for 3h; | 100% |
- 3240-34-4
[bis(acetoxy)iodo]benzene
- 603-35-0
triphenylphosphine
- 100-46-9
benzylamine
A
- 588-46-5
N-(phenylmethyl)acetamide
B
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| Stage #1: [bis(acetoxy)iodo]benzene; triphenylphosphine In chloroform for 1h; Heating; Stage #2: benzylamine In chloroform for 0.166667h; | A 94% B 100% |
- 7312-39-2
3,3-diphenyl-1,2-indanedione
- 21204-67-1
methyl (triphenylphosphoranylidene)acetate
C
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| In benzene at 20℃; for 5h; Wittig reaction; | A 70% B 11% C 100% |
- 7312-39-2
3,3-diphenyl-1,2-indanedione
- 1099-45-2
ethyl (triphenylphosphoranylidene)acetate
C
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| In benzene at 20℃; for 5h; Wittig reaction; | A 65% B 14% C 100% |
- 7312-39-2
3,3-diphenyl-1,2-indanedione
- 16640-68-9
cyanomethylene triphenylphosphorane
C
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| In benzene at 20℃; for 7h; Wittig reaction; | A 63% B 17% C 100% |
- 452296-51-4
(Z)-3-(4-bromophenyl)-3-iodoprop-2-en-1-ol
A
- 869209-22-3
1-bromo-4-((Z)-3-bromo-1-iodopropenyl)benzene
B
- 791-28-6
Triphenylphosphine oxide
| Conditions | Yield |
|---|---|
| With carbon tetrabromide; triphenylphosphine In dichloromethane at 0 - 20℃; | A 100% B n/a |
Triphenylphosphine oxide Chemical Properties
IUPAC Name: Diphenylphosphorylbenzene
Synonyms of Triphenyl Phosphine Oxide (CAS NO.791-28-6): 3-Acetylpropionic acid ; 4-Ketovaleric acid ; 4-Oxopentanoic acid ; Acetopropionic acid ; Levulinic acid ; Propionic acid, 3-acetyl- ; gamma-Ketovaleric acid
CAS NO: 791-28-6
Molecular Formula: C18H15OP
Molecular Weight: 791-28-6
Molecular Structure: 
EINECS: 212-338-8
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 26.88 Å2
Index of Refraction: 1.619
Molar Refractivity: 82.91 cm3
Molar Volume: 236.2 cm3
Surface Tension: 48.2 dyne/cm
Density: 1.17 g/cm3
Flash Point: 233.8 °C
Enthalpy of Vaporization: 69.63 kJ/mol
Boiling Point: 462.9 °C at 760 mmHg
Vapour Pressure: 2.62E-08 mmHg at 25°C
Melting point: 154-158 °C
Storage temp: Store at RT
Solubility methanol: 25 mg/mL, clear
Water solubility: slightly soluble
Appearance: White solid
Product Categories of Triphenyl Phosphine Oxide (CAS NO.791-28-6): Catalysis and Inorganic Chemistry;Phosphine Ligands;Phosphorus Compounds
Triphenylphosphine oxide Uses
Triphenyl Phosphine Oxide (CAS NO.791-28-6) is used for intermediates in organic synthesis and pharmaceutical, and it is also used for catalysts, extraction agents. Besides, it is still used for fluorescent anti-counterfeit powder.
Triphenylphosphine oxide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 450mg/kg (450mg/kg) | National Technical Information Service. Vol. AD607-952, | |
| rabbit | LD50 | skin | > 5gm/kg (5000mg/kg) | Food and Cosmetics Toxicology. Vol. 17, Pg. 847, 1979. | |
| rat | LD50 | oral | 1850mg/kg (1850mg/kg) | Food and Cosmetics Toxicology. Vol. 17, Pg. 847, 1979. |
Triphenylphosphine oxide Safety Profile
Safety Information about Triphenyl Phosphine Oxide (CAS NO.791-28-6):
Hazard Codes: 
Xn,Xi
Risk Statements: 22-36/37/38-52/53
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-61-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany: 2
RTECS: SZ1676000
HS Code: 29310095
Triphenylphosphine oxide Specification
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.
What can I do for you?
Get Best Price
