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Vardenafil hydrochloride

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Vardenafil hydrochloride

EINECS 606-590-1
CAS No. 224785-91-5 Density N/A
PSA 121.28000 LogP 3.82900
Solubility N/A Melting Point 214-216 °C
Formula C23H33ClN6O4S Boiling Point 692.2 °C at 760 mmHg
Molecular Weight 525.06 Flash Point 372.5 °C
Transport Information N/A Appearance White to off-white cyrstalline solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 224785-91-5 (Vardenafil hydrochloride) Hazard Symbols N/A

Piperazine,1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-,monohydrochloride (9CI);Levitra;


Vardenafil hydrochloride Chemical Properties

Molecular structure of Vardenafil hydrochloride(224785-91-5):

Molecular Formula: C23H33ClN6O4S
Molecular Weight: 525.06
H bond acceptors: 10
H bond donors: 1
Freely Rotating Bonds: 8
Polar Surface Area: 108.72Å2
Melting point:  214-216°C
Flash Point: 372.5 °C
Enthalpy of Vaporization: 101.43 kJ/mol
Boiling Point: 692.2 °C at 760 mmHg
Vapour Pressure: 5.17E-19 mmHg at 25°C
Melting Point: 214-216°C
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Vardenafil
SMILES: Cl.O=C2\N=C(/Nn1c(nc(c12)C)CCC)c3cc(ccc3OCC)S(=O)(=O)N4CCN(CC)CC4.O.O.O
InChI: InChI=1/C23H32N6O4S.ClH.3H2O/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H;3*1H2

Vardenafil hydrochloride Uses

 Vardenafil hydrochloride(CAS NO.224785-91-5) is mainly used as a selective phsphodiesterase type 5 (PDE5) inhibitor.

Vardenafil hydrochloride Production

Vardenafil hydrochloride (CAS NO.224785-91-5) can be prepared as follows:

Vardenafil hydrochloride Specification

 Vardenafil hydrochloride (CAS NO.224785-91-5) is a white to off-white cyrstalline solid. Vardenafil hydrochloride (CAS NO.224785-91-5) is also named as 2-(2-Ethoxy-5-((4-ethyl-1-piperazinyl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one Hydrochloride Trihydrate ; 2-{2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate ; 2-{2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate ; 2-{2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-onhydrochloridtrihydrat ; imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-, hydrochloride, hydrate (1:1:3) .

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