Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 


Related Products

Hot Products



EINECS 823-919-6
CAS No. 508233-74-7 Density 1.164 g/cm3
PSA 40.57000 LogP 4.25800
Solubility N/A Melting Point N/A
Formula C18H22N2S Boiling Point 424.833 °C at 760 mmHg
Molecular Weight 298.452 Flash Point 210.732 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 508233-74-7 (Vortioxetine) Hazard Symbols N/A

1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine;Lu AA 21004;

Article Data 56

Vortioxetine Specification

The Vortioxetine, with the CAS registry number 508233-74-7, is also known as Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-. This chemical's molecular formula is C18H22N2S and molecular weight is 298.45. What's more, its systematic name is 1-{2-[(2,4-Dimethylphenyl)sulfanyl]phenyl}piperazine. Its classification code is Antidepressant, anxiolytic. This chemcial is an experimental drug currently under development by Lundbeck and Takeda for the treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD). 

Physical properties of Vortioxetine are: (1)ACD/LogP: 3.371; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.59; (4)ACD/LogD (pH 7.4): 2.19; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 14.17; (7)ACD/KOC (pH 5.5): 2.72; (8)ACD/KOC (pH 7.4): 107.21; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 40.57 Å2; (13)Index of Refraction: 1.643; (14)Molar Refractivity: 92.731 cm3; (15)Molar Volume: 256.485 cm3; (16)Polarizability: 36.761×10-24cm3; (17)Surface Tension: 52.4 dyne/cm; (18)Density: 1.164 g/cm3; (19)Flash Point: 210.732 °C; (20)Enthalpy of Vaporization: 67.939 kJ/mol; (21)Boiling Point: 424.833 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: S(c1ccccc1N2CCNCC2)c3ccc(cc3C)C
(2)Std. InChI: InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 508233-74-7