Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Warfarin sodium

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Warfarin sodium

EINECS 204-929-4
CAS No. 129-06-6 Density 1.307g/cm3
Solubility Melting Point
Formula C19H16NaO4 Boiling Point 515.2oC at 760mmHg
Molecular Weight 330.33 Flash Point 188.8oC
Transport Information UN 1544 6.1/PG 2 Appearance white or yellowish powder
Safety 53-36/37/39-45 Risk Codes 61-28
Molecular Structure Molecular Structure of 129-06-6 (Warfarin sodium) Hazard Symbols VeryT+
Synonyms

3-(a-Acetonylbenzyl)-4-hydroxycoumarinsodium;Aldocumar;Athrombin;Coumadin;Coumadine;Dimantil;Marevam;Orfarin;Panwarfin;Prothromadin;Simarc 2;Sodiumwarfarin;Sofarin;Tintorane;Varfine;Waran;Warfarina;Warfil 5;Zoocoumarin sodium salt;2H-1-Benzopyran-2-one,4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt (9CI);Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, sodium salt (8CI);

 

Warfarin sodium Chemical Properties

Molecular Structure:

Molecular Formula: C19H16NaO4
Molecular Weight: 331.3172
IUPAC Name: Sodium 2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate
Synonyms of Warfarin sodium (CAS NO.129-06-6): (+-)-Warfarin sodium ; 3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin sodium salt ; Aldocumar ; Caswell No. 903A ; Coumadan Sodico ; Coumadin ; Coumadin sodium ; Coumadine ; Coumafene sodium ; Dicusat ; EINECS 204-929-4 ; EPA Pesticide Chemical Code 086003 ; Jantoven ; Marevam ; Marevan ; Orfarin ; Panwarfin ; Prothromadin ; Ratsul soluble ; Simarc ; Sodium coumadin ; Sodium warfarin ; Sodium, ((3-(alpha-acetonylbenzyl)-2-oxo-2H-1-benzopyran-4-yl)oxy)- ; Tintorane ; UNII-6153CWM0CL ; UniWarfin ; Varfine ; Waran ; Warcoumin ; Warfarin, sodium deriv. ; Warfarin, sodium salt ; Warfilone ; Zoocoumarin sodium salt ; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt ; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt (1:1) ; Coumarin, 3-(alpha-acetonylbenzyl)-4-hydroxy-, sodium salt
CAS NO: 129-06-6
Classification Code: Anticoagulant ; Drug / Therapeutic Agent ; Human Data ; Mutation data ; Reproductive Effect 
H bond acceptors: 4
H bond donors: 1
Freely Rotating Bonds: 5
Polar Surface Area: 63.6 Å2

Warfarin sodium Uses

 Warfarin sodium (CAS NO.129-06-6) is used as Anti-clotting drug.

Warfarin sodium Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intravenous 200mg/kg (200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
child TDLo oral 4mg/kg (4mg/kg) BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED) American Journal of Diseases of Children. Vol. 147, Pg. 609, 1993.
dog LD50 intravenous 200mg/kg (200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
dog LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
guinea pig LD50 oral 182mg/kg (182mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
guinea pig LDLo intravenous 543mg/kg (543mg/kg)   Therapie. Vol. 18, Pg. 921, 1963.
mouse LD50 intravenous 160mg/kg (160mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 123, 1969.
mouse LD50 oral 374mg/kg (374mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
rabbit LD50 intravenous 100mg/kg (100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
rabbit LD50 oral 800mg/kg (800mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953.
rat LD50 intravenous 25mg/kg (25mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 123, 1969.
rat LD50 oral 8700ug/kg (8.7mg/kg) BLOOD: HEMORRHAGE Pharmacological Research Communications. Vol. 10, Pg. 445, 1978.
women TDLo oral 300ug/kg/2D (0.3mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Dermatology. Vol. 116, Pg. 444, 1980.

Warfarin sodium Consensus Reports

Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.

Warfarin sodium Safety Profile

Safety Information of Warfarin sodium (CAS NO.129-06-6):
Hazard Codes:T+
Risk Statements:61-28
Safety Statements:53-36/37/39-45
RIDADR:UN 1544 6.1/PG 2
WGK Germany:1
RTECS:GN4725000
HazardClass:6.1(a)
PackingGroup:II
Poison to humans by ingestion. Experimental poison by ingestion and intravenous routes. Human systemic effects by ingestion: dermatitis. Human reproductive effects by ingestion: fetotoxicity, abnormal condition of newborn at birth, other newborn physical effects, and teratogenic effects including developmental abnormalities of the eye and ear, craniofacial area, skin and appendages, musculoskeletal system, cardiovascular system, and gastrointestinal system of the fetus. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. An anticoagulant drug. When heated to decomposition it emits toxic fumes of Na2O.

Warfarin sodium Specification

First Aid Measures of Warfarin sodium (CAS NO.129-06-6):
Ingestion:Give water and induce vomiting. Never give anthing to an unconscious person. Obtain medical attention.
Inhalation:Remove to fresh air. Give CPR and/or oxygen if required.
Skin:Wash with soap and water.
Eyes:Flush with water for 15 minutes.
Storage of Warfarin sodium (CAS NO.129-06-6):
Store at away from heat and open flame. Do not store near feeds and foodstuffs and keep away from children, domestic animals, pets, or wildlife.

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields