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ZM-447439

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Name

ZM-447439

EINECS N/A
CAS No. 331771-20-1 Density 1.282 g/cm3
PSA 97.84000 LogP 4.81930
Solubility N/A Melting Point 117-120 °C
Formula C29H31N5O4 Boiling Point 639.671 °C at 760 mmHg
Molecular Weight 513.596 Flash Point 340.661 °C
Transport Information N/A Appearance Pale yellow solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 331771-20-1 (ZM 447439) Hazard Symbols N/A
Synonyms

N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide;

 

ZM-447439 Chemical Properties

Product Name: N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
Synonyms of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): ZM 447439
CAS NO: 331771-20-1
Molecular Formula of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): C29H31N5O4
Molecular Weight: 513.5875
Molecular Structure:

Polar Surface Area: 97.84 Å2
Index of Refraction: 1.664
Molar Refractivity: 148.482 cm3
Molar Volume: 400.51 cm3
Surface Tension: 61.616 dyne/cm
Density of N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1): 1.282 g/cm3
Flash Point: 340.661 °C
Enthalpy of Vaporization: 94.453 kJ/mol
Boiling Point: 639.671 °C at 760 mmHg

ZM-447439 Uses

 N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1) is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail.

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