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ZOMEPIRAC SODIUM

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ZOMEPIRAC SODIUM

EINECS 264-669-2
CAS No. 64092-48-4 Density N/A
PSA 62.13000 LogP 1.51030
Solubility N/A Melting Point N/A
Formula C15H14 Cl N O3 . Na Boiling Point 470.8°C at 760 mmHg
Molecular Weight 313.716 Flash Point 238.5°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion. Human systemic effects by ingestion: cyanosis. When heated to decomposition it emits toxic fumes of Cl, Na2O, and NOx. Risk Codes 23/24/25
Molecular Structure Molecular Structure of 64092-48-4 (ZOMEPIRAC SODIUM SALT) Hazard Symbols T
Synonyms

1H-Pyrrole-2-aceticacid, 5-(4-chlorobenzoyl)-1,4-dimethyl-, sodium salt (9CI);McN 2783-21-98;Sodium zomepirac;Zomax;Zomepirac sodium;Zomepirac sodium salt;

Article Data 1

ZOMEPIRAC SODIUM Chemical Properties

Product Name: Zomepirac sodium (CAS NO.64092-48-4)


Molecular Formula: C15H13ClNNaO3
Molecular Weight: 313.71g/mol
Mol File: 64092-48-4.mol
Einecs: 264-669-2
Boiling point: 470.8 °C at 760 mmHg
Flash Point: 238.5 °C
Enthalpy of Vaporization: 77.26 kJ/mol
Vapour Pressure: 1.15E-09 mmHg at 25°C
H-Bond Donor: 0
H-Bond Acceptor: 3

ZOMEPIRAC SODIUM Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 100mg/kg (100mg/kg)   Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 23, Pg. 250, 1982.
hamster LD50 oral 743mg/kg (743mg/kg)   Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 23, Pg. 250, 1982.
man TDLo oral 1429ug/kg (1.429mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Annals of Allergy. Vol. 48, Pg. 233, 1982.
mouse LD50 oral 63mg/kg (63mg/kg)   Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 23, Pg. 250, 1982.
rat LD50 oral 27mg/kg (27mg/kg)   Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 23, Pg. 250, 1982.
women LDLo oral 117mg/kg (117mg/kg) BEHAVIORAL: COMA

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
Journal of Analytical Toxicology. Vol. 7, Pg. 223, 1983.
women TDLo oral 16mg/kg/2D-I (16mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Archives of Internal Medicine. Vol. 143, Pg. 1171, 1983.
women TDLo oral 70mg/kg/10D-I (70mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
American Journal of Medicine. Vol. 76, Pg. 1113, 1984.

ZOMEPIRAC SODIUM Safety Profile

Safety Information of Zomepirac sodium (CAS NO.64092-48-4):
Hazard Codes: T
Risk Statements: 23/24/25
23:  Toxic by inhalation 
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
Safety Statements: 22-36/37/39-45
22:  Do not breathe dust
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

ZOMEPIRAC SODIUM Specification

 Zomepirac sodium ,its CAS NO. is 64092-48-4,the synonyms is 1h-Pyrrole-2-aceticacid,5-(4-chlorobenzoyl)-1,4-dimethyl-,sodiumsalt,dihyd ; 5-(4-Chlorobenzoyl)-1,4-dimethyl-1h-pyrrole-2-aceticacidsodiumsaltdihydra ; Mcn2783-21-98 ; Sodium5-(4-chlorobenzoyl)-1,4-dimethyl-1h-pyrrole-2-acetatedihydrate ; Sodiumzomepirac ; Zomax ; Zomepiracsodium ; Zomepirac sodium salt .

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