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10236-47-2

Basic Information
CAS No.: 10236-47-2
Name: Naringin
Molecular Structure:
Molecular Structure of 10236-47-2 (Naringin)
Formula: C27H32O14
Molecular Weight: 580.54
Synonyms: Nvaringin;Momordica grosvenori Extract;schizandra extract;Naringin 98% (HPLC);PolymethoxyLatecl Flavones (Nobiletin);Naringoside;4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy- R-L-mannopyranosyl)-a-D-glucopyranosyl]- oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-,(2S)-;Naringenin 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside];45-diOH-Flavone-7-rhgluc;Naringenin 7-O-neohesperidoside;7-[[2-O-(6-Deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-5-hydroxy-2(S)-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;7-(2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone;
EINECS: 233-566-4
Density: 1.66 g/cm3
Melting Point: 166 °C
Boiling Point: 928.1 °C at 760 mmHg
Flash Point: 308.5 °C
Solubility: Soluble in water, alcohol, acetone and warm acetic acid.
Appearance: beige to yellowish powder
Hazard Symbols: IrritantXi
Risk Codes: 22
Safety: 22-24/25-36
Transport Information:
PSA: 225.06000
LogP: -1.16520
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    MF: C27H32O14 MW: 580.53 EINECS: 233-566-4 Mol File: 10236-47-2.mol Naringin Structure Naringin Chemical Properties Melting point 166 °C alpha -91 º (c=1, C2H5OH) Boiling point 559.35°C (rough estimate) density

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    Naringin

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    Naringin 10236-47-2

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    Naringin

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  • NARINGIN

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    10236-47-2

    NARINGIN

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    Naringin

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Chemistry

IUPAC Name: 7-[(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Synonyms of Naringin (CAS NO.10236-47-2): 5-Hydroxy-2-(4-hydroxyphenyl)-7-(2-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranosyloxy)-4-chromanon ; Naringenin-7-beta-neohesperidoside ; Naringoside ; 4H-1-Benzopyran-4-one, 7-((2-O-(6-deoxy-alpha-L-mannapyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl), (S)- ; 4H-1-Benzopyran-4-one, 7-((2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)- ; 7-(2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone
CAS NO: 10236-47-2
Molecular Formula: C27H32O14
Molecular Weight: 580.54
Molecular Structure:
H bond acceptors: 14
H bond donors: 8
Freely Rotating Bonds: 14
Polar Surface Area: 137.06 Å2
Index of Refraction: 1.708
Molar Refractivity: 135.63 cm3
Molar Volume: 347.8 cm3
Surface Tension: 101.2 dyne/cm
Density: 1.66 g/cm3
Flash Point: 308.5 °C
Enthalpy of Vaporization: 141.42 kJ/mol
Boiling Point: 928.1 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Melting Point: 166 °C
Alpha: -91 º (c=1, C2H5OH)
Storage temp: 0-6°C
Appearance: beige to yellowish powder
Product Categories of Naringin (CAS NO.10236-47-2): Flavanones;Biochemistry;Disaccharides;Flavonoids;Glycosides;Sugars;Natural Plant Extract

Uses

 Naringin (CAS NO.10236-47-2) has obvious anti-inflammation effect. Besides it can reduce blood viscosity and thrombosis. Naringin can also be used for analgesia, calm, and increase the secretion of bile of the experimental animals.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 2gm/kg (2000mg/kg)   Eksperimentalna Meditsina i Morfologiya. Vol. 19, Pg. 207, 1980.
rat LD50 intraperitoneal 2gm/kg (2000mg/kg)   Eksperimentalna Meditsina i Morfologiya. Vol. 19, Pg. 207, 1980.

Safety Profile

Safety information of Naringin (CAS NO.10236-47-2):
Hazard Codes: HarmfulXn
Risk Statements: 22
R22: Harmful if swallowed.
Safety Statements: 22-24/25-36
S22: Do not breathe dust. 
S24/25: Avoid contact with skin and eyes. 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: QN6340000
F: 3

Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Use agent most appropriate to extinguish fire. 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Storage: Store in a cool, dry place. Store in a tightly closed container.