CAS No.105-13-5,4-Methoxybenzyl alcohol Suppliers

Products Categories

Pharmaceutical (162)
Organic Chemicals (44)
Others (35)
Synthetic Flavours & Fragrances (18)
Reagent (8)
Materials (5)
Food Additives (2)
Basic Inorganic Chemicals (2)
Plant Extract (1)

Basic Information

Molecular Structure:
CAS No.:	105-13-5
Name:	4-Methoxybenzyl alcohol
Article Data:	646

Formula:	C₈H₁₀O₂
Molecular Weight:	138.166
Synonyms:	(4-methoxyphenyl)methanol;Anise alcohol;Benzyl alcohol, p-methoxy-;p-Anisyl alcohol;p-Anisol alcohol;Anisyl alcohol;benzenemethanol, 4-methoxy-;4-Methoxybenzyl alcohol (p-Anisic alcohol, 99.0%);Anisyl Alcohol , Natural;4-Methoxybenzyl alcohol;
EINECS:	203-273-6
Density:	1.113 g/mL at 25 °C(lit.)
Melting Point:	22-25 °C(lit.)
Boiling Point:	259 °C(lit.)
Flash Point:	230 °F
Solubility:	insoluble in water
Appearance:	clear colourless to yellowish liquid after melting
Hazard Symbols:	Xn,Xi
Risk Codes:	36/37/38-63-62-41-20/21/22
Safety:	26-45-36/37/39
PSA:	29.46000
LogP:	1.18750

Synthetic route

: 123-11-5
4-methoxy-benzaldehyde

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With trichlorosilane; N,N-dimethyl-formamide In dichloromethane at 0℃; for 6h;	100%
Stage #1: 4-methoxy-benzaldehyde With Dimethylphenylsilane; copper(l) chloride In various solvent(s) at 20℃; for 42h; Reduction; Stage #2: With water; toluene-4-sulfonic acid In various solvent(s) at 20℃; Hydrolysis;	100%
With tri-n-butyl-tin hydride; phenylboronic acid In dichloromethane at 20℃; for 20h;	100%

: 700-13-0
Trimethylhydroquinone

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With pyridine; 3-carboxypyridinium dichromate In dichloromethane for 0.333333h; Product distribution; Ambient temperature; other reagents and ratio of reagents;	100%

: C16H27OS(1+)*BF4(1-)

A: 544-40-1
Dibutyl sulfide

B: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With methylamine at 60℃; for 10h;	A 100% B n/a

: C16H24NO4S(1+)*BF4(1-)

A: 1115-47-5
N-acetyl-DL-methionine

B: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With methylamine at 60℃; for 10h;	A 100% B n/a

: 14629-56-2
trimethyl(4-methoxybenzyloxy)silane

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With iodine In methanol microwave irradiation;	100%
With bismuth(lll) trifluoromethanesulfonate In methanol at 20℃; for 0.0166667h;	98%
With Nafion-H(R); silica gel In hexane at 20℃; for 0.25h;	98%

: 101803-60-5
tert-butyl((4-methoxybenzyl)oxy)dimethylsilane

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With iodine In methanol microwave irradiation;	100%
With 2,6-disulphated cellulose In methanol at 25℃; for 0.5h; Catalytic behavior; Solvent; Time; Green chemistry;	97%
With hafnium tetrakis(trifluoromethanesulfonate) In methanol at 20℃; for 3h;	97%

: 18494-82-1
2-(4-methoxy-benzyloxy)-tetrahydro-pyran

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With aluminium trichloride; 1-benzyl-4-aza-1-azoniabicyclo[2.2.2]octane dichromate; (3,4-dimethoxyphenyl)methanol for 0.0333333h;	100%
With sulfuric acid; silica gel In methanol at 20℃; for 0.5h;	98%
With methanol at 20℃; for 0.5h;	98%

: C32H36BO8(1-)*Na(1+)

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With water	100%

: 121-98-2
methyl 4-methoxybenzoate

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With C56H70Cl3N10Ru2(1+)*F6P(1-); potassium tert-butylate; hydrogen In tetrahydrofuran; dodecane at 70℃; under 37503.8 Torr; for 16h; Inert atmosphere; Glovebox; Autoclave;	99.8%
With 2-pyrrolidinon; samarium diiodide Reagent/catalyst; Glovebox;	99%
With dimethylsulfide borane complex In 2-methyltetrahydrofuran at 90℃; under 7500.75 Torr; for 0.333333h; Inert atmosphere; Flow reactor; chemoselective reaction;	99%

: 104-21-2
p-methoxybenzyl acetate

: 105-13-5
4-Methoxybenzyl alcohol

Conditions

Conditions	Yield
With methanol; potassium permanganate at 25℃; chemoselective reaction;	99%
With zirconocene dichloride; diisobutylaluminium hydride In tetrahydrofuran at -20℃; Inert atmosphere; regioselective reaction;	97%
Stage #1: p-methoxybenzyl acetate With phenylsilane; fac-[Mn-(xantphos)(CO)3Br] at 100℃; for 6h; Inert atmosphere; Stage #2: With water; sodium hydroxide In methanol at 20℃; Inert atmosphere;	97%

Raw Materials

100-46-9

824-94-2

108-91-8

Downstream Products

637-69-4

101-77-9

104-47-2

Total:187 Page 1 of 5 1 2 3 4 5 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 105-13-5

Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The CAS registry number of Anisic alcohol is 105-13-5. Its EINECS registry number is 203-273-6. The IUPAC name is (4-methoxyphenyl)methanol. 4-Methoxybenzyl alcohol is also called p-Anise Alcohol; p-Anisyl alcohol; Methoxybenzenemethanol; 4-methoxy-Benzenemethanol; Benzenemethanol,4-methoxy-; p-methoxy-benzyl alcohol; 4-methoxyphenol; 4-methoxy-1,3-benzothiazol-2-amine. In addition, the molecular formula is C₈H₁₀O₂. What's more, it is a clear colourless to yellowish liquid after melting. It can be used in organic synthesis and used as a solvent and food flavor.

Physical properties about Anisic alcohol are: (1)ACD/LogP: 0.944; (2)ACD/LogD (pH 5.5): 0.94; (3)ACD/LogD (pH 7.4): 0.94; (4)ACD/BCF (pH 5.5): 3.07; (5)ACD/BCF (pH 7.4): 3.07; (6)ACD/KOC (pH 5.5): 77.76; (7)ACD/KOC (pH 7.4): 77.76; (8)#H bond acceptors: 2 ; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.531; (12)Molar Refractivity: 39.383 cm³; (13)Molar Volume: 127.252 cm³; (14)Polarizability: 15.613 10-24cm³; (15)Surface Tension: 38.7470016479492 dyne/cm; (16)Density: 1.086 g/cm³; (17)Flash Point: 110.271 °C; (18)Enthalpy of Vaporization: 52.47 kJ/mol; (19)Boiling Point: 258.999 °C at 760 mmHg; (20)Vapour Pressure: 0.00700000021606684 mmHg at 25°C

Preparation of Anisic alcohol: it can be prepared by anise, methanal and sodium hydroxide in the presence of ethanol through cannizzaro reaction. After the reaction, through a series of extraction by benzene, acidification by acetic acid, neutralization by sodium hydrogen carbonate, washing, distillation and vacuum distillation you can get the desired product.

Uses of Anisic alcohol: it can be used to get 4-methoxy-benzaldehyde and 4-methoxy-benzonitrile. This reaction will need reagents aq. NH₃, NiSO₄-K₂S₂O₈ and NaOH, and solvent H₂O. The reaction time is 1.5 hours with ambient temperature. The yield is about 8%.

4-Methoxybenzyl alcohol can be used to get 4-methoxy-benzaldehyde and 4-methoxy-benzonitrile

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. In addition, it may has risk of impaired fertility and harm to the unborn child. During using it, wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. And in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.).

You can still convert the following datas into molecular structure:
(1)SMILES: COc1ccc(CO)cc1;
(2)InChI: InChI=1/C8H10O2/c1-10-8-4-2-7(6-9)3-5-8/h2-5,9H,6H2,1H3;
(3)InChIKey: MSHFRERJPWKJFX-UHFFFAOYAE;

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	oral	1600uL/kg (1.6mL/kg)	Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 26, 1948.
mouse	LD50	skin	> 10mL/kg (10mL/kg)	Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 26, 1948.
rabbit	LD50	skin	3gm/kg (3000mg/kg)	Food and Cosmetics Toxicology. Vol. 12, Pg. 825, 1974.
rat	LD50	oral	1200uL/kg (1.2mL/kg)	Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 26, 1948.

Premium Related Products

Anisic alcohol