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10535-17-8

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Basic Information
CAS No.: 10535-17-8
Name: veratrylglycerol-beta-guaiacyl ether
Article Data: 35
Molecular Structure:
Molecular Structure of 10535-17-8 (veratrylglycerol-beta-guaiacyl ether)
Formula: C18H22 O6
Molecular Weight: 334.369
Synonyms: 1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(o-methoxyphenoxy)- (6CI,7CI,8CI);1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol;3-(4,3-Dimethoxyphenyl)-2-glyceryl 2-methoxyphenyl ether; Adlerol;Veratryglycerol b-guaiacylether; Veratrylglycerol b-(o-methoxyphenyl) ether; Veratrylglycerol b-guaiacyl ether
Density: 1.214g/cm3
Melting Point: 97.5-98.5 °C
Boiling Point: 530.7°C at 760 mmHg
Flash Point: 274.8°C
PSA: 77.38000
LogP: 2.18570
Related products
Synthetic route
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol; ethyl acetate for 1h;100%
With sodium tetrahydroborate In methanol at 25℃; for 4h;76%
With sodium tetrahydroborate
With sodium tetrahydroborate In ethanol at 20℃; for 15h;
94687-10-2

ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;89%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; Inert atmosphere;78%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3h; Inert atmosphere; Reflux;46%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; for 3h;
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;

C21H26O6

64-19-7

acetic acid

A

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

C

32565-77-8

3-acetoxy-2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-propanone

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In water at 60℃; for 24h;A 8%
B 53%
C 13%
...Expand

C21H26O6

A

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; water at 80℃; for 15h; Temperature; Solvent;A 18%
B 30%
94757-79-6

<2-Methoxy-phenoxy>-veratroyl-essigsaeure-aethylester

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
22675-96-3

2-methoxyphenoxy-3',4'-dimethoxyacetophenone

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3
2: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water; 1,4-dioxane / 23 h
2: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
2: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
1835-02-5

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 2 h / Reflux
2: potassium carbonate / water; 1,4-dioxane / 23 h
3: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 20 °C
2: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
3: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
90-05-1

2-methoxy-phenol

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
3: sodium tetrahydroborate / ethanol / 6 h / 80 °C
4: potassium carbonate / acetone / 4.5 h / Reflux
5: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
56606-57-6

ethyl 2-bromo-3-(3,4-dimethoxy phenyl)-3-oxopropanoate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylformamide
2: LiAlH4
View Scheme
4687-37-0

ethyl 3,4-dimethoxybenzoylacetate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Br2 / CHCl3
2: dimethylformamide
3: LiAlH4
View Scheme
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    Zhejiang Jiuzhou Chemical Co.,Ltd is a market-oriented and innovation-driven biopharmaceutical company. The company is focusing on the R&D, manufacturing and sales of pharmaceutica

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  • 1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

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    Bide Pharmatech Ltd., founded in 2007, focuses on the field of organic chemistry by providing organic reagents, functional materials, biochemical reagents and bulk drug intermediat

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     China (Mainland)  |  Contact Details

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    10535-17-8

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    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

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    Business Type:Trading Company

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  • 10535-17-8

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    10535-17-8

    10535-17-8

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    Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

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    China (Mainland)  |  Contact Details

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  • 1 -(3,4-Dimethoxyphenyl)-2-(2- methoxyphenoxy)propane-1 ,3-diol

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    10535-17-8

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    Min.Order: 0

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    1.Custom synthetic service could be provided and COA/HPLC/HNMR is available. 2.Professional synthesis laboratory and production base. 3.Strong synthesis team and service team.4.Professional data management system.5.We provide the professional test da

    Shanghai Rechem science Co., Ltd. is specialized in R&D of active drug molecules and customized chemical synthesis. Our company follows closely the industry trend, and the latest r

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    China (Mainland)  |  Contact Details

    Business Type:Other

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    10535-17-8

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  • Nanjing Norris Pharm Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-13901585132

    Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China

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    10535-17-8

    1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-

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    United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

    United Scientific Company (USC) Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. USC has both the expertise and flexibility

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-53535353

    Address:28F No.900 huaihai Road Shanghai China

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  • Casno:

    10535-17-8

    1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol

    Min.Order: 0

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    Cool Pharm Ltd, found in 11805,is a high-tech enterprise which provides customer synthesis service for domestic and international pharmaceutical companies according to international standards. Our business includes research , development, process opt

    Jinan YSPharma Biotechnology Co., Ltd is a large group specializing in contract manufacturing to the pharmaceutical, agrochemical and Fine chemicals with top quality products and s

  • coolpharm Ltd

    China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-531-8233381 86-18678657237

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