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Basic Information
CAS No.: 10535-17-8
Name: veratrylglycerol-beta-guaiacyl ether
Article Data: 35
Molecular Structure:
Molecular Structure of 10535-17-8 (veratrylglycerol-beta-guaiacyl ether)
Formula: C18H22 O6
Molecular Weight: 334.369
Synonyms: 1,3-Propanediol,1-(3,4-dimethoxyphenyl)-2-(o-methoxyphenoxy)- (6CI,7CI,8CI);1-(3,4-Dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol;3-(4,3-Dimethoxyphenyl)-2-glyceryl 2-methoxyphenyl ether; Adlerol;Veratryglycerol b-guaiacylether; Veratrylglycerol b-(o-methoxyphenyl) ether; Veratrylglycerol b-guaiacyl ether
Density: 1.214g/cm3
Melting Point: 97.5-98.5 °C
Boiling Point: 530.7°C at 760 mmHg
Flash Point: 274.8°C
PSA: 77.38000
LogP: 2.18570
Synthetic route
10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In ethanol; ethyl acetate for 1h;100%
With sodium tetrahydroborate In methanol at 25℃; for 4h;76%
With sodium tetrahydroborate
With sodium tetrahydroborate In ethanol at 20℃; for 15h;
94687-10-2

ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;89%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; Inert atmosphere;78%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 3h; Inert atmosphere; Reflux;46%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 60℃; for 3h;
With sodium tetrahydroborate In tetrahydrofuran; water at 20℃;

C21H26O6

64-19-7

acetic acid

A

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

C

32565-77-8

3-acetoxy-2-(2-methoxyphenoxy)-1-(3,4-dimethoxyphenyl)-1-propanone

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In water at 60℃; for 24h;A 8%
B 53%
C 13%

C21H26O6

A

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

B

10548-77-3

1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one

Conditions
ConditionsYield
With oxygen; nitric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran; water at 80℃; for 15h; Temperature; Solvent;A 18%
B 30%
94757-79-6

<2-Methoxy-phenoxy>-veratroyl-essigsaeure-aethylester

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
With lithium aluminium tetrahydride
22675-96-3

2-methoxyphenoxy-3',4'-dimethoxyacetophenone

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3
2: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / water; 1,4-dioxane / 23 h
2: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
2: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
1835-02-5

2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 2 h / Reflux
2: potassium carbonate / water; 1,4-dioxane / 23 h
3: sodium tetrahydroborate / ethyl acetate; ethanol / 1 h
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 20 °C
2: potassium carbonate / 1,4-dioxane / 18 h / 35 °C
3: sodium tetrahydroborate / ethanol / 15 h / 20 °C
View Scheme
90-05-1

2-methoxy-phenol

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3
2: K2CO3
3: NaBH4
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 4.5 h / Reflux
2: sodium tetrahydroborate / methanol / 4 h / 25 °C
3: sodium tetrahydroborate / ethanol / 6 h / 80 °C
4: potassium carbonate / acetone / 4.5 h / Reflux
5: sodium tetrahydroborate / methanol / 4 h / 25 °C
View Scheme
56606-57-6

ethyl 2-bromo-3-(3,4-dimethoxy phenyl)-3-oxopropanoate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylformamide
2: LiAlH4
View Scheme
4687-37-0

ethyl 3,4-dimethoxybenzoylacetate

10535-17-8

1-(3,4-dimethoxyphenyl)-2-(methoxyphenoxy)propane-1,3-diol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Br2 / CHCl3
2: dimethylformamide
3: LiAlH4
View Scheme
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    China (Mainland)  |  Contact Details

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    10535-17-8

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    10535-17-8

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     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:021-61629020

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  • veratrylglycerol-beta-guaiacyl ether

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    10535-17-8

    veratrylglycerol-beta-guaiacyl ether

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    10535-17-8

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

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  • Casno:

    10535-17-8

    veratrylglycerol-beta-guaiacyl ether

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    High quality, competitive price, fast delivery and first-class service we possesses have won the trust and praise of customers. Standard: BP/USP/EP The purity is equal or greater than 99%. As a supplier, we can provide high-quality produc

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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  • 10535-17-8

  • Casno:

    10535-17-8

    10535-17-8

    Min.Order: 0

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    Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

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    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-25-83697070

    Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

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