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| CAS No.: | 1056624-11-3 |
|---|---|
| Name: | 2-(4-(piperazin-1-yl)phenyl)pyrimidine hydrochloride |
| Article Data: | 3 |
| Molecular Structure: | |
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| Formula: | C14H16N4.ClH |
| Molecular Weight: | 276.769 |
| Synonyms: | 2,4,6,8-Tetrahydroxy-pyrimido[5,4-d]pyrimidine |
| Appearance: | Yellow power |
| PSA: | 41.05000 |
| LogP: | 2.74900 |
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- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 1219080-61-1IMIDAZOLE-2-BORONIC ACID
- 942189-35-7
4-(4-pyrimidin-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
| Conditions | Yield |
|---|---|
| With hydrogenchloride In 1,4-dioxane; dichloromethane | |
| With hydrogenchloride In 1,4-dioxane; dichloromethane for 2h; | |
| With hydrogenchloride In 1,4-dioxane; dichloromethane for 2h; |
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1.1: ammonium chloride / tetrahydrofuran; hexanes; water / 0.08 h 1.2: 1 h 2.1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 8 h / 80 °C 3.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h View Scheme |
- 352437-09-3
tert-butyl 4-(4-bromophenyl)piperazine-1-carboxylate
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexanes / 0.5 h / -78 °C 1.2: 18.17 h / 20 °C 2.1: ammonium chloride / tetrahydrofuran; hexanes; water / 0.08 h 2.2: 1 h 3.1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 8 h / 80 °C 4.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h View Scheme |
- 457613-78-4
4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylboronic acid
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 8 h / 80 °C 2: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h View Scheme |
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1.1: triethylamine / dichloromethane / 1 h 2.1: n-butyllithium / tetrahydrofuran; hexanes / 0.5 h / -78 °C 2.2: 18.17 h / 20 °C 3.1: ammonium chloride / tetrahydrofuran; hexanes; water / 0.08 h 3.2: 1 h 4.1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 8 h / 80 °C 5.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h View Scheme |
- 942189-34-6
1-carboxymethyl-pyrrolidine-3-carboxylic acid methyl ester
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
- 942189-36-8
1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-3-carboxylic acid methyl ester
| Conditions | Yield |
|---|---|
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide for 24h; |
- 1056623-86-9
1-tert-butoxycarbonylmethyl-3-methoxymethyl-pyrrolidine-3-carboxylic acid methyl ester
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
- 942189-79-9
3-methoxymethyl-1-{2-oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-3-carboxylic acid methyl ester
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In 1,2-dimethoxyethane for 4h; |
- 1056624-11-3
2-(4-piperazin-1-yl-phenyl)-pyrimidine hydrochloride
- 79-04-9
chloroacetyl chloride
| Conditions | Yield |
|---|---|
| With triethylamine In dichloromethane at 0℃; for 0.5h; |
- Total:27 Page 1 of 1 1
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