CAS No.10595-95-6,N-NITROSO-METHYL-ETHYLAMINE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	10595-95-6
Name:	N-NITROSO-METHYL-ETHYLAMINE
Article Data:	2

Formula:	C3H8 N2 O
Molecular Weight:	88.1093
Synonyms:	Ethylamine,N-methyl-N-nitroso- (7CI,8CI); Ethylmethylnitrosamine; Methylethylnitrosamine;Methylethylnitrosoamine; N-Methyl-N-nitrosoethanamine;N-Methyl-N-nitrosoethylamine; N-Nitroso-N-methylethylamine;N-Nitrosoethylmethylamine; N-Nitrosomethylethylamine; NEMA;Nitrosomethylethylamine
EINECS:	204-825-9
Density:	0.96 g/cm³
Boiling Point:	154.4 ºC
Flash Point:	47.2 ºC
Hazard Symbols:	T
Risk Codes:	25-36/37/38-40
Safety:	Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also NITROSAMINES.
Analytical Methods:		For occupational chemical analysis use OSHA: #38.
PSA:	32.67000
LogP:	0.61950

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Chemistry

Chemistry informtion about N-Nitrosomethylethylamine (10595-95-6) is:
IUPAC Name: N-ethyl-N-methylnitrous amide
Synonyms: N-Nitroso-Mmthyl-Ethylamine ; 1-Ethyl-1-methyl-2-oxohydrazine ; Ethanamine, N-methyl-N-nitroso- ; Ethylamine, N-methyl-N-nitroso- ; Ethylmethylnitrosamine ; Methylaethylnitrosamin ; Methylethylnitrosoamine ; N,N-Methylethylnitrosamine
MF: C₃H₈N₂O
MW: 88.11
Density: 0.96 g/cm³
Flash Point: 47.2 °C
Boiling Point: 154.4 °C at 760 mmHg
Enthalpy of Vaporization: 37.5 kJ/mol
Vapour Pressure: 4.1 mmHg at 25°C
Following is the molecular structure of N-Nitrosomethylethylamine (10595-95-6) is:

Toxicity Data With Reference

1.	mma-sat 500 µg/plate	CRNGDP Carcinogenesis. 5 (1984),1091.
2.	pic-esc 100 mg/L	TCMUE9 Topics in Chemical Mutagenesis. 1 (1984),91.
3.	orl-rat TD:420 mg/kg/71W-C:ETA,REP	ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103.
4.	orl-rat LD50:90 mg/kg	ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103.

Consensus Reports

IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 ,1978,p. 221.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also NITROSAMINES.
For occupational chemical analysis use OSHA: #38.
RIDADR: 2810
HazardClass: 6.1(b)
PackingGroup: III

Standards and Recommendations

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen

Analytical Methods

For occupational chemical analysis use OSHA: #38.

Specification

N-Nitrosomethylethylamine (10595-95-6) is carcinogenic in rats after its oral administration, the only species and route tested: it produces hepatocellular carcinomas.