Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products > 107 > 

107-15-3

Products Categories

Basic Information
CAS No.: 107-15-3
Name: Ethylenediamine
Article Data: 238
Cas Database
Molecular Structure:
Molecular Structure of 107-15-3 (Ethylenediamine)
Formula: C2H8N2
Molecular Weight: 60.0989
Synonyms: Ethylenediamine (USP/JP14);Edamine;1,2-ethanediamine;ethane-1,2-diamine;Ethylendiamin;NCI-C60402;EthylenediamineAnhydrous;Ethyliminum;EDA;
EINECS: 203-468-6
Density: 0.898 g/cm3
Melting Point: 8.5 °C(lit.)
Boiling Point: 119.7 °C at 760 mmHg
Flash Point: 93 °F
Solubility: Miscible with water
Appearance: clear liquid
Hazard Symbols: CorrosiveC
Risk Codes: 10-21/22-34-42/43
Safety: 23-26-36/37/39-45
Transport Information: UN 1604 8/PG 2
PSA: 52.04000
LogP: 0.30440
  • Display:default sort

    New supplier

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Consensus Reports

Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.

Standards and Recommendations

OSHA PEL: TWA 10 ppm
ACGIH TLV: TWA 10 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 10 ppm (25 mg/m3)
DOT Classification:  8; Label: Corrosive, Flammable Liquid

Analytical Methods

1,2-ETHANEDIAMINE's Analytical Methods:For occupational chemical analysis use OSHA: #ID-60 or NIOSH: Ethylenediamine, 2540.

Specification

The Ethylenediamine is colorless liquid with an ammonia-like odor. It belongs to the categories of (1)Pharmaceutical Intermediates ; (2)alpha,omega-Alkanediamines ; (3)alpha,omega-Bifunctional Alkanes ; (4)Biochemistry ; (5)Reagents for Oligosaccharide Synthesis. With cas registry number of 107-15-3, it also has other registry numbers including 8030-24-8 and 85404-18-8. Its IUPAC name and systematic name are the same which is called ethane-1,2-diamine with SMILES: NCCN. The superlist name about this chemical are (1)1,2-Diaminoethane ; (2) Ethylenediamine ; (3) Ethylenediamine ; (4) Ethylenediamine [UN1604] [Corrosive] ; (5) UN1604 .

Physical properties about this chemical are: (1) # of Rule of 5 Violations: 0 ; (2) ACD/LogD (pH 5.5): -5.97 ; (3) ACD/LogD (pH 7.4): -4.53 ; (4) ACD/BCF (pH 5.5): 1 ; (5) ACD/BCF (pH 7.4): 1 ; (6) ACD/KOC (pH 5.5): 1 ; (7) ACD/KOC (pH 7.4): 1 ; (8) #H bond acceptors: 2 ; (9) #H bond donors: 4 ; (10) #Freely Rotating Bonds: 3 ; (11) Index of Refraction: 1.446 ; (12) Molar Refractivity: 18.38 cm3 ; (13) Molar Volume: 68.9 cm3 ; (14) Surface Tension: 36.8 dyne/cm ; (15) Density: 0.872 g/cm3 ; (16) Flash Point: 33.9 °C ; (17) Enthalpy of Vaporization: 37.98 kJ/mol; (18) Refractive index: n20/D 1.4565(lit.); (19) Sensitive: Air Sensitive; (20) Boiling Point: 119.7 °C at 760 mmHg ; (21) Vapour Pressure: 15.8 mmHg at 25°C.

Preparation of Ethylenediamine : this chemical is prepared by the reaction of ammonia and 1,2-dichloroethane . This reaction can give the mixture of ethylenediamine and the linear polyamines.
ClCH2CH2Cl + 4 NH3 → H2NCH2CH2NH2 + 2 NH4Cl

Uses of Ethylenediamine : this compound is mainly used for production of many chemicals. Here is a example.


This reaction will use the solvent water and AcOK / AcOH buffer, pH = 5. The yield is about 30%.

When you are using this chemical, please be cautious about it as the following:
A human poison by inhalation. Experimental poison by inhalation, intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion and skin contact. Experimental reproductive effects. Corrosive. A severe skin and eye irritant. An allergen and sensitizer. Mutation data reported. Flammable liquid when exposed to heat, flame, or oxidizers. Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, CS2, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, HCl, mesityl oxide, HNO3, oleum, AgClO4, H2SO4, β-propiolactone, or vinyl acetate. To fight fire, use CO2, dry chemical, alcohol foam. When heated to decomposition it emits toxic fumes of NOx and NH3.

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 100mg/kg (100mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935.
guinea pig LD50 oral 470mg/kg (470mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

GASTROINTESTINAL: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
human TCLo inhalation 200ppm (200ppm) PERIPHERAL NERVE AND SENSATION: PARESTHESIS AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 223, 1954.
mouse LC50 inhalation 300mg/m3 (300mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 66, 1982.
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   Chimica Therapeutica. Vol. 4, Pg. 136, 1969.
mouse LD50 oral 1gm/kg (1000mg/kg) BEHAVIORAL: ATAXIA Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (1), Pg. 38, 1997.
rabbit LD50 skin 730uL/kg (0.73mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rabbit LDLo subcutaneous 500mg/kg (500mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1295, 1935.
rat LCLo inhalation 4000ppm/8H (4000ppm)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LD50 intraperitoneal 76mg/kg (76mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 454, 1972.
rat LD50 oral 1200mg/kg (1200mg/kg) BEHAVIORAL: ATAXIA Meditsina Truda i Promyshlennaya Ekologiya. Industrial Medicine and Ecology. Vol. (1), Pg. 38, 1997.
rat LD50 subcutaneous 300mg/kg (300mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 66, 1982.