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107-97-1

Basic Information
CAS No.: 107-97-1
Name: Glycine,N-methyl-
Molecular Structure:
Molecular Structure of 107-97-1 (Glycine,N-methyl-)
Formula: C3H7NO2
Molecular Weight: 89.09
Synonyms: Sarcosine(8CI);(Methylamino)acetic acid;(Methylamino)ethanoic acid;2-(Methylamino)acetic acid;Acetic acid, (methylamino)-;Methylglycine;N-Methylaminoaceticacid;N-Methylglycine;Sarcosin;Sarcosinic acid;
EINECS: 203-538-6
Density: 1.093 g/cm3
Melting Point: 208-212 °C (dec.)(lit.)
Boiling Point: 195.1 °C at 760 mmHg
Flash Point: 71.8 °C
Solubility: 1480 g/L (20 °C) in water
Appearance: white crystalline powder
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 24/25-36-26
Transport Information:
PSA: 49.33000
LogP: -0.31870
Synthetic route
Conditions
ConditionsYield
With recombinant mouse glycine N-methyltransferase In aq. buffer at 30℃; for 0.333333h; pH=8; Reagent/catalyst; Enzymatic reaction;
5616-81-9

sarcosine tert-butyl ester

107-97-1

sarcosine

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 20℃; for 2h;
107-16-4

glycolonitrile

74-89-5

methylamine

107-97-1

sarcosine

Conditions
ConditionsYield
With water das entstechende Nitril wird durch konz. Salzsaeure verseift;
With water; sodium hydroxide at 25℃; for 1h; Inert atmosphere;
Stage #1: glycolonitrile; methylamine at 20℃; for 1h; Inert atmosphere;
Stage #2: With water; sodium hydroxide
52605-49-9

sarcosine ethyl ester hydrochloride

107-97-1

sarcosine

Conditions
ConditionsYield
With bromine; triethylamine In dichloromethane; water; ethyl acetate
50-00-0

formaldehyd

56-40-6

glycine

107-97-1

sarcosine

Conditions
ConditionsYield
With sodium dihydrogenphosphate; zinc at 30℃; for 0.116667h;90%
With hydrogenchloride; water
1083159-08-3

O2-(2,4-dinitrophenyl) 1-[N-(carboxymethyl)-N-methylamino]diazen-1-ium-1,2-diolate

107-97-1

sarcosine

Conditions
ConditionsYield
With GLUTATHIONE; diethylenetriaminopentaacetic acid In dimethyl sulfoxide at 37℃; pH=7.4; aq. phosphate buffer; Inert atmosphere;
1071-83-6

N-(phosphonemethyl)glycine

107-97-1

sarcosine

Conditions
ConditionsYield
With Pseudomonas putida T5 glyphosate C-P lyase In aq. phosphate buffer at 30℃; pH=7; Kinetics; Enzymatic reaction;
76110-01-5

luzopeptin C

A

107-97-1

sarcosine

B

312-84-5

D-Serine

C

77421-34-2

L-β-hydroxy-N-methylvaline

D

56-40-6

glycine

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 18h; Further byproducts given;
76110-01-5

luzopeptin C

A

107-97-1

sarcosine

B

312-84-5

D-Serine

C

77421-33-1

3-hydroxy-6-methoxyquinoline-2-carboxylic acid

D

56-40-6

glycine

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 18h; Further byproducts given;
74-90-8

hydrogen cyanide

carbon

carbon

A

107-97-1

sarcosine

B

56-40-6

glycine

C

302-72-7

rac-Ala-OH

D

107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With ammonia; water at -196℃; Further byproducts given;A 0.24 mmol
B 3.0 mmol
C 0.18 mmol
D 0.17 mmol
60-27-5

creatinine

107-97-1

sarcosine

Conditions
ConditionsYield
Bei langandauernder Faeulnis;
With barium dihydroxide at 100℃; im Rohr;
79-11-8

chloroacetic acid

74-89-5

methylamine

107-97-1

sarcosine

Conditions
ConditionsYield
With water at 40℃;
With water
859960-32-0

N-methyl-N-phenylmethanesulfonyl-glycine

107-97-1

sarcosine

Conditions
ConditionsYield
With hydrogenchloride Hydrolysis.im geschlossenen Rohr;
98-98-6

2-Picolinic acid

107-97-1

sarcosine

34557-54-5

methane

7664-41-7

ammonia

A

107-97-1

sarcosine

B

56-40-6

glycine

C

2835-81-6

2-aminobutanoic acid

Conditions
ConditionsYield
With hydrogen byproducts: dl-α-amino-butiric acid, dl-alanine, β-alanine; by electric spark discharge or electric discharge;
1056469-56-7

C10H22N2O

A

107-97-1

sarcosine

B

(R)-2-heptylamine
123-82-0, 6240-90-0, 7795-34-8, 44745-29-1

(R)-2-heptylamine

Conditions
ConditionsYield
With novozyme 435; water at 70℃; for 147h; pH=7; aq. phosphate buffer; Enzymatic reaction;
C11H16N2O

C11H16N2O

A

107-97-1

sarcosine

B

3886-69-9

(R)-1-phenyl-ethyl-amine

Conditions
ConditionsYield
With novozyme 435; water at 70℃; for 120h; pH=7; aq. phosphate buffer; Enzymatic reaction;

(S)-3-Hydroxy-3-methyl-2-methylamino-butyric acid (R)-2-(carboxymethyl-methyl-carbamoyl)-2-[(3-hydroxy-6-methoxy-quinoline-2-carbonyl)-amino]-ethyl ester

A

107-97-1

sarcosine

B

77421-34-2

L-β-hydroxy-N-methylvaline

C

77431-62-0

(R)-3-Hydroxy-2-[(3-hydroxy-6-methoxy-quinoline-2-carbonyl)-amino]-propionic acid

Conditions
ConditionsYield
With water; hydroxide
74-89-5

methylamine

C

C

A

107-97-1

sarcosine

B

600-21-5

N-methylalanine

C

617-45-8

aspartic Acid

Conditions
ConditionsYield
With ammonia Yield given. Further byproducts given. Yields of byproduct given;
Conditions
ConditionsYield
With sodium azide; sulfuric acid; SC(NH2)2 In water; acetic acid at 25℃; Rate constant; other solvent; other catalysts;
With perchloric acid; ammonium sulfamate; sodium thiocyanide at 50℃; Rate constant; piperidinium perchlorate, 18h; transnitrosating studies;
74-89-5

methylamine

C

C

A

107-97-1

sarcosine

B

56-40-6

glycine

C

302-72-7

rac-Ala-OH

D

107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With ammonia Yield given. Further byproducts given. Yields of byproduct given;
56-40-6

glycine

A

107-97-1

sarcosine

B

5473-12-1

N-methylglycine methylester

C

556-50-3

glycylglycine

D

142-73-4

iminodiacetic acid

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen at 180℃; under 300.03 Torr; for 0.166667h;
46376-16-3

2-(N-methylphenylsulfonamido)acetic acid

107-97-1

sarcosine

Conditions
ConditionsYield
With sulfuric acid at 125 - 130℃;
616-34-2

methoxycarbonylmethylamine

A

34037-21-3

morpholine-2,5-dione

B

107-97-1

sarcosine

C

5473-12-1

N-methylglycine methylester

D

6096-81-7

dimethyl iminodiacetate

E

56-40-6

glycine

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen at 180℃; under 300.03 Torr; for 0.166667h;
79760-89-7

C16H19N2O4P

A

107-97-1

sarcosine

B

701-64-4

phosphoric acid monophenyl ester

C

106-49-0

p-toluidine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane for 0.0833333h;

cordyheptapeptides B

A

107-97-1

sarcosine

B

61-90-5

L-leucine

C

2566-30-5

N-Methyl-L-phenylalanine

D

147-85-3

L-proline

Conditions
ConditionsYield
With hydrogenchloride at 110℃; for 15h; Further byproducts. Title compound not separated from byproducts.;
Conditions
ConditionsYield
With Canyon Diablo iron meteorites at 140℃; for 24h; Reagent/catalyst; Temperature;
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

107-97-1

sarcosine

Conditions
ConditionsYield
With barium dihydroxide; water
With barium dihydroxide
5616-32-0

(methylamino)acetonitrile

107-97-1

sarcosine

Conditions
ConditionsYield
With barium dihydroxide; water
With barium dihydroxide

perthamide C

A

107-97-1

sarcosine

B

4144-02-9

O-methyl-L-threonine

C

7423-92-9

o-hydroxyl-phenylalanine

D

6734-41-4

cis-4-methyl-(S)-proline

Conditions
ConditionsYield
With hydrogenchloride; water at 130℃;
107-97-1

sarcosine

64-17-5

ethanol

52605-49-9

sarcosine ethyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 78℃;100%
With hydrogenchloride99%
With hydrogenchloride at 20℃; for 72h;95%
With hydrogenchloride
With acetyl chloride for 3h; Reflux;
107-97-1

sarcosine

501-53-1

benzyl chloroformate

39608-31-6

N-(Benzyloxycarbonyl)sarcosine

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water at 20℃;100%
With sodium carbonate In 1,4-dioxane; water 1.) 0 deg C, 1.5 h, 2.) room temperature, 11 h;99%
With sodium hydroxide In water at 0 - 20℃; for 16h;94%
67-56-1

methanol

107-97-1

sarcosine

13515-93-0

N-methylglycine methyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride for 6.5h; Cooling; Reflux; Inert atmosphere;100%
With thionyl chloride at 55℃; for 2h;92%
With thionyl chloride 1.) ice-salt bath, 20 min, 2.) room temperature, 2 h, 3.) reflux, 2 h;90%
107-97-1

sarcosine

24424-99-5

di-tert-butyl dicarbonate

13734-36-6

N-(tert-butoxycarbonyl)sarcosine

Conditions
ConditionsYield
With triethylamine In water for 6h;100%
With triethylamine In water at 25℃; for 3h;97%
With sodium hydroxide In 1,4-dioxane95%
107-97-1

sarcosine

A

50-00-0

formaldehyd

B

124-38-9

carbon dioxide

C

74-89-5

methylamine

Conditions
ConditionsYield
With hydrogenchloride; sodium hydroxide; sodium perchlorate; chlorine at 24.9℃; Mechanism; Rate constant; Equilibrium constant; multistep reaction: 1.) water, 298 deg K, 2.) water, 298 deg K; reactions under var. conditions;A 100%
B n/a
C n/a
50-00-0

formaldehyd

107-97-1

sarcosine

552-89-6

2-nitro-benzaldehyde

365275-13-4

3-methyl-5-(2'-nitrophenyl)oxazolidine

Conditions
ConditionsYield
In toluene for 1h; Heating;100%
In benzene for 1h; Heating;95%
Conditions
ConditionsYield
In toluene C60, C20H10N4((C4H9)2C6H3)3(C6H4)2(C10H2N2O4)(CHO), N-methylglycine (toluene) heated under N2 in dark for 6 h; cooled to 25°C, evapd. to dryness (reduced pressure); chromy. sepd., dissolved (CH3Cl), added Zn(OAc)2 in CH3OH, heated for 30 min; washed twice (H2O), dried (anhydrous Na2SO4), solvent evapd., chromy., reprecipitated from benzene-methanol;100%
50-00-0

formaldehyd

107-97-1

sarcosine

(Z)-4-(2-ethoxybenzylidene)-2-phenyloxazol-5(4H)-one

(5R*,9R*)-9-(2-ethoxyphenyl)-7-methyl-2-phenyl-3-oxa-1,7-diazaspiro[4.4]non-1-en-4-one

Conditions
ConditionsYield
In benzene for 5h; Reflux; Dean-Stark; diastereoselective reaction;100%
107-97-1

sarcosine

56-53-1

diethylstilbestrol

C18H20O2*C3H7NO2

Conditions
ConditionsYield
In methanol at 20℃;99.01%
67-56-1

methanol

107-97-1

sarcosine

5473-12-1

N-methylglycine methylester

Conditions
ConditionsYield
With thionyl chloride at 0℃; for 3.5h;99%
With thionyl chloride
(i) SOCl2, (ii) /BRN= 1098229/; Multistep reaction;
at 0 - 20℃; for 12h;
107-97-1

sarcosine

2-(Diethoxy-phosphoryl)-thioacetimidic acid methyl ester; hydriodide

{[2-(Diethoxy-phosphoryl)-acetimidoyl]-methyl-amino}-acetic acid

Conditions
ConditionsYield
With pyridine In dichloromethane at 260℃;99%
941-69-5

N-phenyl-maleimide

73568-29-3

2-chloro-6-methoxyquinolin-3-carboxaldehyde

107-97-1

sarcosine

(3aR,6aS)-4-(6-Methoxy-2-oxo-1,2-dihydro-quinolin-3-yl)-5-methyl-2-phenyl-tetrahydro-pyrrolo[3,4-c]pyrrole-1,3-dione

(3aR,6aS)-4-(6-Methoxy-2-oxo-1,2-dihydro-quinolin-3-yl)-5-methyl-2-phenyl-tetrahydro-pyrrolo[3,4-c]pyrrole-1,3-dione

Conditions
ConditionsYield
In xylene for 2h; Heating;99%
3612-20-2

1-phenylmethyl-4-piperidone

107-97-1

sarcosine

336191-70-9

2-[(1-benzyl-4-piperidyl)(methyl)amino]acetic acid

Conditions
ConditionsYield
With triethanolamine; acetic acid; trifluoroacetic acid In 1,2-dichloro-ethane99%
50-00-0

formaldehyd

107-97-1

sarcosine

117133-77-4

(E)-methyl-3-(benzo[d][1,3]dioxol-5-yl)-2-cyanoacrylate

methyl (3RS,4RS)-4-(1,3-benzodioxol-5-yl)-3-cyano-1-methylpyrrolidine-3-carboxylate

Conditions
ConditionsYield
In toluene for 1.33333h; Reflux; stereospecific reaction;99%
50-00-0

formaldehyd

107-97-1

sarcosine

14479-58-4

methyl (E)- 2-cyano-3-(4-methoxyphenyl)prop-2-enoate

methyl (3RS,4RS)-3-cyano-4-(4-methoxyphenyl)-1-methylpyrrolidine-3-carboxylate

Conditions
ConditionsYield
In toluene for 1.25h; Reflux; stereospecific reaction;99%
107-97-1

sarcosine

912676-30-3

α-naphthyl isoselenocyanate

1310370-46-7

1-methyl-3-(1-naphthyl)-2-selenoxohydantoin

Conditions
ConditionsYield
In 1,4-dioxane at 100℃; for 3.5h;99%
107-97-1

sarcosine

1217-89-6

1-benzylisatin

13672-24-7

ethyl (2E)-(1-benzyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetate

C36H33N3O4

Conditions
ConditionsYield
In ethanol at 20℃; for 2h; diastereoselective reaction;99%
107-97-1

sarcosine

1217-89-6

1-benzylisatin

(3S*,5’S*)-1,1’’-dibenzyl-3’-methyldispiro[indoline-3,4’-oxazolidine-5’,3’’-indoline]-2,2’’-dione

Conditions
ConditionsYield
In dimethyl sulfoxide at 20℃; for 4h; Green chemistry; diastereoselective reaction;99%
With 3-nitro-2-(trifluoromethyl)-2H-chromene In isopropyl alcohol at 55 - 60℃; for 5h;43%
50-00-0

formaldehyd

72167-88-5

4-phenylsulphonyl-2H-chromene-2-one

107-97-1

sarcosine

127599-33-1

1,3-dihydro-2-methyl-pyrrolo(3,4-c)chromene-4-one

Conditions
ConditionsYield
In benzene for 3h; Heating;98%
50-00-0

formaldehyd

107-97-1

sarcosine

99-61-6

3-nitro-benzaldehyde

3-methyl-5-(3-nitro-phenyl)-oxazolidine

Conditions
ConditionsYield
In benzene for 1h; Heating;98%

(3E,5E)-1-methyl-3,5-bis(4-fluorobenzylidene)piperidin-4-one

107-97-1

sarcosine

82-86-0

acenaphthene quinone

1-methyl-4-(4-fluorophenyl)pyrrole(spiro[2.2'']acenaphthene-1''-one)-spiro[3.3']-5'-(4-fluorophenylmethylidene)-1'-methyltetrahydro-4'(1'H)-pyridinone

Conditions
ConditionsYield
In methanol for 1h; Reflux; stereoselective reaction;98%
In methanol for 1h; Heating;97%

(3E,5E)-3,5-bis(2-chlorobenzylidene)-1-methylpiperidin-4-one

107-97-1

sarcosine

82-86-0

acenaphthene quinone

1-methyl-4-(2-chlorophenyl)pyrrole(spiro[2.2'']acenaphthene-1''-one)-spiro[3.3']-5'-(2-chlorophenylmethylidene)-1'-methyltetrahydro-4'(1'H)-pyridinone

Conditions
ConditionsYield
In methanol for 1h; Heating;98%

C8H9NOC12H8F2

107-97-1

sarcosine

82-86-0

acenaphthene quinone

1-methyl-4-(3-fluorophenyl)pyrrole(spiro[2.2'']acenaphthene-1''-one)-spiro[3.3']-5'-(3-fluorophenylmethylidene)-1'-methyltetrahydro-4'(1'H)-pyridinone

Conditions
ConditionsYield
In methanol for 1h; Reflux; stereoselective reaction;98%
In methanol for 1h; Heating;96%
107-97-1

sarcosine

4369-12-4

(E)-1-methyl-3,5-bis(4-methoxybenzylidene)-4-piperidone

82-86-0

acenaphthene quinone

1-methyl-4-(4-methoxyphenyl)pyrrole(spiro[2.2'']acenaphthene-1''-one)-spiro[3.3']-5'-(4-methoxyphenylmethylidene)-1'-methyltetrahydro-4'(1'H)-pyridinone

Conditions
ConditionsYield
In methanol for 1h; Heating;98%
50-00-0

formaldehyd

762173-03-5

2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridine-7-carbaldehyde

107-97-1

sarcosine

762173-04-6

2-(4-fluorophenyl)-7-(3-methyloxazolidin-5-yl)-3-(methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
In toluene for 12h; Heating;98%
107-97-1

sarcosine

14223-48-4

p-chlorophenyl isoselenocyanate

1310370-38-7

3-(p-chlorophenyl)-1-methyl-2-selenoxohydantoin

Conditions
ConditionsYield
In 1,4-dioxane at 100℃; for 5h;98%
107-97-1

sarcosine

1353546-25-4

C21H17NO

17630-76-1

5-chloroindole 2,3-dione

C31H26ClN3O2

Conditions
ConditionsYield
In 1,4-dioxane; methanol Reflux; stereoselective reaction;98%
107-97-1

sarcosine

1353546-31-2

(E)-2-[4-chlorobenzylidene]-3,4-dihydro-1(2H)-acridinone

91-56-5

indole-2,3-dione

C30H24ClN3O2

Conditions
ConditionsYield
In 1,4-dioxane; methanol for 6h; Reflux; stereoselective reaction;98%
107-97-1

sarcosine

25554-84-1

2-(ethoxycarbonothioylthio)acetic acid

59857-32-8

N-(ethoxycarbonothioyl)-N-methylglycine

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃; for 48h;98%
With sodium hydroxide In water at 25℃; for 72h;
In water
With sodium hydroxide In water
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    Business Type:Other

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    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

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    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

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    Business Type:Trading Company

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    Business Type:Lab/Research institutions

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    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

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    Business Type:Trading Company

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    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

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    107-97-1

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    Business Type:Trading Company

    Tel:15032793961

    Address:Federal Business Plaza, Qiaoxi District,Shijiazhuang

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  • Casno:

    107-97-1

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    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

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    107-97-1

    Sarcosine

    Min.Order: 1 Kiloliter

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    Hangzhou Ocean Chemical Co.ltd is a comprehensive chemical enterprise which mainly integrates R&D, production, marketing business of chemical in lab-pack, semi-bulk and bulk-quanti

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88025872, 28272092, 28272096

    Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China

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    107-97-1

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    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

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    107-97-1

    MSDS/COA Download

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    107-97-1

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    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

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    107-97-1

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    Address:95A, Xingyuan East Road, Zhangdian District

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    107-97-1

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    Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care

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    Business Type:Lab/Research institutions

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    Address:Building 3 of Innovation Park, East District of the National University Science Park

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    Business Type:Lab/Research institutions

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    107-97-1

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    Business Type:Lab/Research institutions

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    107-97-1

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    Triumph International Development Limilted is engaged in the API, pharmaceutical intermediates research and developmen.Adhering to the "customer first" business philosophy,we suppl

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    BaiFuChem is a Professional chemical raw material supplier in China, our main products include Biochemical , Pharma Intermediate and Organic chemical etc. BaiFuChem have wealth of products,experience , expertise and state-of-the-art equ

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    Business Type:Other

    Tel:+86 592 605 6448

    Address:No.31 Pingshan South Road, HaiCang District, Xiamen, China

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    107-97-1

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    Prime Molecular Co., Ltd. is an advanced chemical intermediates manufacture with ?two R&D centers and two production sites in China, all well-equipped with dedicated and profession

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    107-97-1

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    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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    107-97-1

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    Business Type:Lab/Research institutions

    Tel:+86-571-87396432

    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

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  • Casno:

    107-97-1

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    Min.Order: 1 Kilogram

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    Henan Bizhi Chemical Tech Co Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production an

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-371-86658258

    Address:University Science Park

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    107-97-1

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    Qingdao Sigma Chemical Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc. Our Labo

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History

Sarcosine was first isolated and named by the German chemist Justus von Liebig in 1847, while Jacob Volhard first synthesized it in 1862.

Specification

The Sarcosine is an amino acid intermediate in the metabolism of choline. The IUPAC name of this chemical is 2-(methylamino)acetic acid. With the CAS registry number 107-97-1, it is also named as Glycine, N-methyl-. The product's categories are amino acids series;sarcosine [sar];amino acids. It is white crystalline powder with a sweetish taste. And it is soluble in water, ethanol and dilute ethanol, insoluble in ether. Additionally, people should keep this chemical in cool and dry place and keep away from fire, heat and water.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.79; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.29; (4)ACD/LogD (pH 7.4): -3.29; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.431; (13)Molar Refractivity: 21.1 cm3; (14)Molar Volume: 81.4 cm3; (15)Polarizability: 8.36×10-24 cm3; (16)Surface Tension: 37.1 dyne/cm; (17)Enthalpy of Vaporization: 47.54 kJ/mol; (18)Vapour Pressure: 0.184 mmHg at 25°C; (19)Rotatable Bond Count: 2; (20)Exact Mass: 89.047678; (21)MonoIsotopic Mass: 89.047678; (22)Topological Polar Surface Area: 49.3; (23)Heavy Atom Count: 6; (24)Complexity: 52.8.

Preparation of Sarcosine: Digesting the bark of Quillaia saponaria by hot water or aqueous ethanol, then using ether or acetone to make it precipitation. Finally, we can get the product by re-crystallization and refining.

Uses of Sarcosine: It is used as biochemical reagent, dye stabilizer, daily chemical, amino acid surfactants, health drugs fatigue recovery agent and so on. It also can react with ethanol to get N-methyl-glycine ethyl ester. This reaction needs reagent aqueous HCl.


 
When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin, so people should avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.
1. SMILES:O=C(O)CNC
2. InChI:InChI=1/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6) 
3. InChIKey:FSYKKLYZXJSNPZ-UHFFFAOYAL

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