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1072015-52-1

Basic Information
CAS No.: 1072015-52-1
Name: (R)-Tetrahydrofuran-3-amine hydrochloride
Molecular Structure:
Molecular Structure of 1072015-52-1 ((R)-Tetrahydrofuran-3-amine hydrochloride)
Formula: C4H9NO.ClH
Molecular Weight: 123.582
Synonyms: Josiphos SL-J001-2
PSA: 35.25000
LogP: 1.23630
Synthetic route
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

1-(6-ethyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)piperidin-4-one

(R)-1-(6-ethyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydrofuran-3-yl)piperidin-4-amine

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃;91%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

C19H19FN4O2

(R)-1-(8-fluoro-4,6-dimethyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydrofuran-3-yl)piperidin-4-amine

Conditions
ConditionsYield
Stage #1: [(3R)-tetrahydrofuran-3-yl]ammonium chloride; C19H19FN4O2 With N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃; for 0.166667h;
Stage #2: With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃;
87%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

1-(6-ethyl-8-fluoro-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)piperidin-4-one

(R)-1-(6-ethyl-8-fluoro-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydrofuran-3-yl)piperidin-4-amine

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃;77%
Stage #1: [(3R)-tetrahydrofuran-3-yl]ammonium chloride; 1-(6-ethyl-8-fluoro-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)piperidin-4-one With N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃; for 0.166667h;
Stage #2: With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; for 3h;
68%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

3-(5-hydroxy-1H-indazo-1-yl)benzoic acid

3-(5-hydroxy-1H-indazol-1-yl)-N-[(3R)-tetrahydrofuran-3-yl]benzamide

Conditions
ConditionsYield
Stage #1: [(3R)-tetrahydrofuran-3-yl]ammonium chloride; 3-(5-hydroxy-1H-indazo-1-yl)benzoic acid With triethylamine In dichloromethane at 20℃; for 20h; Inert atmosphere;
Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In dichloromethane; ethyl acetate at 0 - 20℃; for 1h; Inert atmosphere;
73%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

1-(6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)piperidin-4-one

(R)-1-(6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydrofuran-3-yl)piperidin-4-amine

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid; N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 20℃;73%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

4,6-dichloro-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl] pyridine-3-carboxamide

6-chloro-N-((R)-2-fluoro-3-hydroxy-3-methylbutyl)-4-(((R)-tetrahydrofuran-3-yl)amino) nicotinamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 120℃; for 12h;69%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

4-chloro-7,8-dimethoxyquinazoline

(R)-7,8-dimethoxy-N-(tetrahydrofuran-3-yl)quinazolin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 100℃; for 3h;67%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 100℃; for 3h;67%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

6-amino-4-fluoronicotinonitrile

(R)-6-amino-4-((tetrahydrofuran-3-yl)amino)nicotinonitrile

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 110℃; Inert atmosphere;66%
1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

5437-45-6

Benzyl bromoacetate

(R)-benzyl 2-((tetrahydrofuran-3-yl)amino)acetate

Conditions
ConditionsYield
Stage #1: [(3R)-tetrahydrofuran-3-yl]ammonium chloride With triethylamine In tetrahydrofuran at 0℃; for 0.333333h;
Stage #2: Benzyl bromoacetate With sodium iodide In tetrahydrofuran at 0 - 20℃;
60.6%
897030-99-8

4-chloro-5-iodo-6-methyl-pyrimidin-2-ylamine

1072015-52-1

[(3R)-tetrahydrofuran-3-yl]ammonium chloride

1220812-14-5

(R)-5-iodo-6-methyl-N4-(tetrahydrofuran-3-yl)pyrimidine-2,4-diamine

Conditions
ConditionsYield
With triethylamine In ethanol; water Reflux;54%
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  • (R)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE  CAS NO.1072015-52-1

  • Casno:

    1072015-52-1

    (R)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE CAS NO.1072015-52-1

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    Changchun Haofei Import and Export Trade Co. , Ltd is located in Changchun, Changchun, Jilin Province. We are a modern high-tech private enterprise specializing in the R & D, Produ

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

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  • (R)-Tetrahydrofuran-3-amine hydrochloride

  • Casno:

    1072015-52-1

    (R)-Tetrahydrofuran-3-amine hydrochloride

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    Strong R&D strength and team We have a R&D team with around 30 R&D personnel.All of our employees have chemical backgrounds and have worked in the chemical industry for many years.Our laboratory can synthesize target products with wei

    Changzhou Pesan Chemical Co., Ltd. is a dynamic and specialized chemical company. Since our establishment, We provide raw materials and key intermediates for pharmaceutical industr

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     China (Mainland)  |  Contact Details

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  • Casno:

    1072015-52-1

    (R)-Tetrahydrofuran-3-amine hydrochloride

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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  • Casno:

    1072015-52-1

    (R)-tetrahydrofuran-3-amine hydrochloride

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

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  • (R)-(-)-3-Pyrrolidinol hydrochloride

  • Casno:

    1072015-52-1

    (R)-(-)-3-Pyrrolidinol hydrochloride

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    1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

    Chemical Technology Co.,LTD is a professional enterprise which engaged in pharmaceutical intermediates, material intermediates production research and development.Company foc

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     China (Mainland)  |  Contact Details

    Business Type:Other

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  • (3R)-oxolan-3-amine hydrochloride

  • Casno:

    1072015-52-1

    (3R)-oxolan-3-amine hydrochloride

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    It is composed of professionals with senior industry background and rich market experience. More than 90% of the personnel have chemistry, chemical, pharmaceutical or related professional knowledge. They are all rigorously trained and evaluated, and

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-025-58912721

    Address:Kai Tuo Road NO.8,Jiangning District,Nanjing,jiangsu Province,china

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  • Casno:

    1072015-52-1

    (3R)-oxolan-3-amine hydrochloride

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    Reply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g

    Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. was established in 2008, is mainly engaged in customizing services for Pharmaceutical intermediates and active molecular API for 15 y

  • Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-21-57721279

    Address:Science and Technology Park, Songjiang District, Shanghai, China

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  • (R)-Tetrahydro-furan-3-ylamine hydrochloride

  • Casno:

    1072015-52-1

    (R)-Tetrahydro-furan-3-ylamine hydrochloride

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    R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

    Nanjing Norris Pharm Technology Co., Ltd., born in July, 2012, is a new company registered in Nanjing, Jiangsu Province,China. Norris grows tremendously since 2012.Till Dec.31,2015

  • Nanjing Norris Pharm Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-13901585132

    Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China

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  • (R)-(-)-3-Pyrrolidinol hydrochloride

  • Casno:

    1072015-52-1

    (R)-(-)-3-Pyrrolidinol hydrochloride

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    Aopharm is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in modes of

    AOPHARM is a comprehensive manufacturer and an international distribution of chemicals throughout the world. Specialized in APIs, advanced intermediates, botanical extract and colo

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     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:0086-311-66600578

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  • Casno:

    1072015-52-1

    (R)-Tetrahydrofuran-3-amine hydrochloride

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    FOB Price:  USD $ 0.0-0.0

    low price Application: Pharmaceutical Intermediates

    ■ Company Business Shanghai Rainbow Chemicals Co., Ltd., an emerging hi-tech enterprise, specializes in the research, development, production and sale of fine chemical industrial a

  • Shanghai Rainbow Chemistry Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-64968086-5815/5812

    Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China

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  • Casno:

    1072015-52-1

    (R)-Tetrahydrofuran-3-amine hydrochloride

    Min.Order: 0

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    United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innov

    United Scientific Company (USC) Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. USC has both the expertise and flexibility

  • Shanghai united Scientific Co.,Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-53535353

    Address:28F No.900 huaihai Road Shanghai China

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  • (R)-Tetrahydrofuran-3-amine hydrochloride

  • Casno:

    1072015-52-1

    (R)-Tetrahydrofuran-3-amine hydrochloride

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Guangdong Raffles PharmaTech Co., Ltd providing:CAS#1228780-72-0, the most competitive price, best quality. We can provide efficient services and the best packaging. Welcome inquiries and orders from all over the world. If you have more questions or

    Established in August 2011, Guangdong Raffles PharmaTech Co., Ltd is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceut

  • Shenzhen HwaGen Pharmaceutical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-752-5538396

    Address:Guangdong Huizhou China

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  • (R)-tetrahydrofuran-3-amine hydrochloride

  • Casno:

    1072015-52-1

    (R)-tetrahydrofuran-3-amine hydrochloride

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    At Capot,We can synthesize and purify your complex molecules from 100 gram to 10 tons.Appearance:Clear colorless to light yellow liquid Storage:Dry,Seal and Cool place Package:1G,5G,10G,25G,100G,250G,500G,1KG,5KG,10KG,25KG,50KG,100KG,150KG,200KG. App

    Welcome to Capot . Established in 1996 ,Capot Chemical Co.,Ltd is a fine organics manufacturing facility which located in Hangzhou,P.R.China. We produce a wide range of organics,

  • Capot Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-85586718

    Address:join hands science park,NO.4028 nanhuan road,hanghzou ,zhejiang,china

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