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CAS No.: | 1110813-31-4 |
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Name: | Dacomitinib (PF299804) |
Article Data: | 9 |
Molecular Structure: | |
Formula: | C24H25ClFN5O2 |
Molecular Weight: | 469.94 |
Synonyms: | PF299804; pf-00299804-03; (2e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-2-butenamide; (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-Methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide; pf-299 |
Density: | 1.344 |
Melting Point: | >187°C (dec.) |
Boiling Point: | 665.7±55.0 °C(Predicted) |
Solubility: | DMSO, Methanol (Sparingly) |
Appearance: | White to Off-White Solid |
PSA: | 79.38000 |
LogP: | 5.23900 |
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Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.