Products Categories
| CAS No.: | 111406-87-2 |
|---|---|
| Name: | Zileuton |
| Molecular Structure: | |
|
|
|
| Formula: | C11H12N2O2S |
| Molecular Weight: | 236.294 |
| Synonyms: | A64077;Leutrol;N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea;Urea,N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-;Zyflo; |
| EINECS: | 601-087-3 |
| Density: | 1.401 g/cm3 |
| Melting Point: | 157-158 °C |
| Boiling Point: | 449.4 °C at 760 mmHg |
| Flash Point: | 225.6 °C |
| Appearance: | crystalline solid |
| Hazard Symbols: | Xn |
| Risk Codes: | 22-36 |
| Safety: | 26 |
| PSA: | 94.80000 |
| LogP: | 3.43250 |
- 144851-82-1METHYL2-AMINO-3-FLUOROBENZOATE
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 1219080-61-1IMIDAZOLE-2-BORONIC ACID
- 97-99-42-Furanmethanol,tetrahydro-
- 108-62-3Metaldehyde
- 32233-40-2(-)-Corey lactone diol
- 9002-07-7Trypsin
- 613-62-7Naphthalene,2-(phenylmethoxy)-
- 54-20-62,4(1H,3H)-Pyrimidinedione,5-(trifluoromethyl)-
- 106-14-912-Hydroxystearicacid
- 71939-50-93,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol,decahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
History
Zileuton was introduced by Abbott Laboratories in 1996 and is now marketed in two formulations by Cornerstone Therapeutics Inc. under the brand names ZYFLO and ZYFLO CR.
Specification
The Zileuton, with the CAS registry number 111406-87-2,is also known as 1-(1-Benzothiophen-2-ylethyl)-1-hydroxy-urea. It belongs to the product categories of Pharmaceuticals;Amines;Aromatics. Its EINECS number is 231-791-2. This chemical's molecular formula is C11H12N2O2S and molecular weight is 236.29. What's more,Its systematic name is Urea,N-(1-benzo(b)thien-2-ylethyl)-N-hydroxy-.It is a Crystalline Solid which is an inhibitor of 5-lipoxygenase,the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. It is used as an antiasthmatic.
Physical properties about Zileuton are:
(1)ACD/LogP: 2.704; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.70; (4)ACD/LogD (pH 7.4): 2.70; (5)ACD/BCF (pH 5.5): 66.81; (6)ACD/BCF (pH 7.4): 66.2; (7)ACD/KOC (pH 5.5): 704.39; (8)ACD/KOC (pH 7.4): 698.24; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.704; (13)Molar Refractivity: 65.486 cm3; (14)Molar Volume: 168.657 cm3; (15)Surface Tension: 68.8489990234375 dyne/cm; (16)Density: 1.401 g/cm3; (17)Flash Point: 225.612 °C; (18)Enthalpy of Vaporization: 74.625 kJ/mol; (19)Boiling Point: 449.437 °C at 760 mmHg; (20)Vapour Pressure: 0 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)O=C(N)N(O)C(c2sc1ccccc1c2)C;
(2)Std. InChI:InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14);
(3)Std. InChIKey:MWLSOWXNZPKENC-UHFFFAOYSA-N.