Products Categories
CAS No.: | 112713-92-5 |
---|---|
Name: | 1-Cyclopentene-1-heptanoic acid, 5-oxo-3-[(triethylsilyl)oxy]-, Methyl ester |
Molecular Structure: | |
Formula: | C19H34O4Si |
Molecular Weight: | 354.562 |
Synonyms: | Methyl 7-(5-oxo-3-((triethylsilyl)oxy)cyclopent-1-en-1-yl)heptanoate;Methyl 5-oxo-3-<(triethylsilyl)oxy>-1-cyclopenteneheptanoate;methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate;(+-)-methyl 7-[(3-triethylsilyloxy) 5-oxocyclopenten 1-yl]heptanoate;methyl 5-oxo-3-[(triethylsilyl)oxy]-1-cyclopentene-1-heptanoate; |
Density: | 0.99±0.1 g/cm3(Predicted) |
Boiling Point: | 413.2±45.0 °C(Predicted) |
PSA: | 52.60000 |
LogP: | 4.78960 |
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
misoprostol
Conditions | Yield |
---|---|
With (lithium)2(CN)(methyl)2cuprate In tetrahydrofuran; water; acetic acid | 91% |
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-[(1R,2R,3R)-2-((E)-5-Fluoro-4-methyl-4-trimethylsilanyloxy-oct-1-enyl)-5-oxo-3-trimethylsilanyloxy-cyclopentyl]-heptanoic acid methyl ester
Conditions | Yield |
---|---|
With (lithium)2(CN)(methyl)2cuprate In tetrahydrofuran | 68% |
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-{(1R,2R,3R)-5-Oxo-2-[(E)-4-(1-propyl-cyclopropyl)-4-trimethylsilanyloxy-pent-1-enyl]-3-trimethylsilanyloxy-cyclopentyl}-heptanoic acid methyl ester
Conditions | Yield |
---|---|
With (lithium)2(CN)(methyl)2cuprate In tetrahydrofuran | 63% |
4-methyl-4-trimethylsilyloxyl-1-octyne
trimethylaluminum
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-[(1R,2R,3R)-2-((E)-2,4-Dimethyl-4-trimethylsilanyloxy-oct-1-enyl)-5-oxo-3-triethylsilanyloxy-cyclopentyl]-heptanoic acid methyl ester
Conditions | Yield |
---|---|
With zirconocene dichloride 1) CH2Cl2, 0 deg C to r.t. 2) THF, Et2O, 0 deg C; Yield given. Multistep reaction; |
4-methyl-4-trimethylsilyloxyl-1-octyne
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-[(1R,2R,3R)-2-((E)-4-Methyl-4-trimethylsilanyloxy-oct-1-enyl)-5-oxo-3-triethylsilanyloxy-cyclopentyl]-heptanoic acid methyl ester
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
(1E)-(4R)-4-trimethylsilyloxy-4-methyl-1-iodo-1octene
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-[(1R,2R,3R)-2-((E)-4-Methyl-4-trimethylsilanyloxy-oct-1-enyl)-5-oxo-3-triethylsilanyloxy-cyclopentyl]-heptanoic acid methyl ester
Conditions | Yield |
---|---|
With n-butyllithium; methyllithium 1.) THF, -78 deg C, 1 h, 2.) -78 deg C; Yield given. Multistep reaction; |
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-[(1R,2R,3R)-5-Oxo-3-triethylsilanyloxy-2-((E)-3-trimethylsilanyloxy-hept-1-enyl)-cyclopentyl]-heptanoic acid methyl ester
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
7-((1R,2R,3R)-2-{(E)-3-[(1,1-Dimethyl-butyl)-dimethyl-silanyloxy]-3-methyl-oct-1-enyl}-5-oxo-3-triethylsilanyloxy-cyclopentyl)-heptanoic acid methyl ester
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
chloro-trimethyl-silane
2-methylallylmagnesium chloride
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
Conditions | Yield |
---|---|
With copper(I) bromide dimethylsulfide complex; lithium chloride In tetrahydrofuran at -78℃; for 0.25h; |
prenylmagnesium bromide
methyl 7-(5-oxo-3-[(triethylsilyl)-oxy]-1-cyclopenten-1-yl)-heptanoate
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; copper(I) bromide dimethylsulfide complex; tetrabutyl ammonium fluoride; lithium chloride 1.) THF, -78 deg C, 5 min, 2. ) THF, 10 min; Yield given. Multistep reaction. Yields of byproduct given; |