CAS No.115550-35-1,Marbofloxacin Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	115550-35-1
Name:	Marbofloxacin

Formula:	C₁₇H₁₉FN₄O₄
Molecular Weight:	362.36
Synonyms:	Marbocyl;Marbofloxacine;9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylic acid;Marbofloxacin [INN];CCRIS 8212;Marbofloxacine [INN-French];Marbofloxacino;Marbofloxacinum;7H-Pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-;
EINECS:	640-416-5
Density:	1.55 g/cm³
Melting Point:	268-269 ºC
Boiling Point:	570.5 ºC at 760 mmHg
Flash Point:	298.8 ºC
Solubility:	Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml
Appearance:	yellow or primrose yellow powder
Hazard Symbols:	Xi
Risk Codes:	52/53-36/37/38
Safety:	61-36-26
PSA:	78.25000
LogP:	0.57620

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Chemistry

Product Name: Marbofloxacin
Synonyms of Marbofloxacin (CAS NO.115550-35-1): Marbofloxacin [INN] ; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylic acid ; CCRIS 8212 ; Marbofloxacine ; Marbofloxacine [INN-French] ; Marbofloxacino ; Marbofloxacino [INN-Spanish] ; Marbofloxacinum ; Marbofloxacinum [INN-Latin] ; UNII-8X09WU898T ; 7H-Pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-
CAS NO: 115550-35-1
Classification Code: Drug / Therapeutic Agent ; Enzyme inhibitors
Molecular Formula: C₁₇H₁₉FN₄O₄
Molecular Weight: 362.3556
Molecular Structure:

Melting Point: 268-269°C
Polar Surface Area: 65.56 Å²
Index of Refraction: 1.701
Molar Refractivity: 90.37 cm³
Molar Volume: 233.5 cm³
Surface Tension: 78.3 dyne/cm
Density: 1.55 g/cm³
Flash Point: 298.8 °C
Enthalpy of Vaporization: 90.02 kJ/mol
Boiling Point: 570.5 °C at 760 mmHg
Vapour Pressure: 7.45E-14 mmHg at 25°C

Uses

Marbofloxacin (CAS NO.115550-35-1) is used in veterinary medicine under the trade names Marbocyl and Zeniquin. It can be used both orally and topically. Marbofloxacin (CAS NO.115550-35-1) is particularly used for infections of the skin, respiratory system and mammary glands, as well as with urinary tract infections in dogs.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	> 2gm/kg (2000mg/kg)		United States Patent Document. Vol. #4801584,

Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 52/53-36/37/38
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 61-36-26
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
S36: Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS: UU8815140

Specification

Mechanism of action: Marbofloxacin (CAS NO.115550-35-1) is a quinolone, and acts by inhibiting bacterial DNA replication.

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