Products Categories
| CAS No.: | 118-93-4 |
|---|---|
| Name: | 2'-Hydroxyacetophenone |
| Article Data: | 314 |
| Cas Database | |
| Molecular Structure: | |
|
|
|
| Formula: | C8H8O2 |
| Molecular Weight: | 136.15 |
| Synonyms: | Acetophenone,2'-hydroxy- (8CI);Acetophenone, o-hydroxy- (3CI);1-(2-Hydroxyphenyl)ethanone;1-(6-Hydroxyphenyl)ethanone;2-Acetylphenol;2-Hydroxyphenyl methyl ketone;2-Hydroxyphenylethanone;2'-Hydroxyacetophenone;Methyl 2-hydroxyphenyl ketone;NSC 16933;NSC 44452;NSC 83568;NSC 9263;o-Acetylphenol;o-Hydroxyacetophenone;o-Hydroxyhypnone;o-Hydroxyphenyl methyl ketone; |
| EINECS: | 204-288-0 |
| Density: | 1.131 g/cm3 |
| Melting Point: | 3-6 °C(lit.) |
| Boiling Point: | 218.4 °C at 760 mmHg |
| Flash Point: | 87.5 °C |
| Solubility: | Slightly soluble in water |
| Appearance: | Light yellow liquid |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36/37/39 |
| PSA: | 37.30000 |
| LogP: | 1.59480 |
- 144851-82-1METHYL2-AMINO-3-FLUOROBENZOATE
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 1219080-61-1IMIDAZOLE-2-BORONIC ACID
- 64042-56-4
O-Ethoxycarbonyl-o-acetylphenol
- 118-93-4
o-hydroxyacetophenone
| Conditions | Yield |
|---|---|
| With sodium hydrogen telluride In ethanol for 0.5h; Quantum yield; Heating; buffer: deoxygen. acetic acid; | 100% |
- 70538-46-4
1-(2-((3-methylbut-2-en-1-yl)oxy)phenyl)ethanone
- 118-93-4
o-hydroxyacetophenone
| Conditions | Yield |
|---|---|
| With titanium tetrachloride; tetra-(n-butyl)ammonium iodide In dichloromethane at -78℃; for 0.5h; deprenylation; | 100% |
- 4940-39-0
acide chromone carboxylique-2
- 107-15-3
ethylenediamine
A
- 118-93-4
o-hydroxyacetophenone
B
- 89221-22-7
5-(o-hydroxyphenyl)-2,3-dihydro-1,4-diazepine-7-carboxylic acid
| Conditions | Yield |
|---|---|
| In pyridine; methanol at 50℃; for 408h; | A n/a B 99.1% |
| Conditions | Yield |
|---|---|
| With β‐cyclodextrin In water at 60℃; for 0.133333h; Microwave irradiation; | 99% |
| With ytterbium(III) chloride In neat (no solvent) at 70 - 120℃; for 0.0333333h; Microwave irradiation; Green chemistry; | 98% |
| With β‐cyclodextrin In water; acetone at 60℃; for 5h; Green chemistry; | 93% |
| With sodium perborate In methanol at 25℃; for 0.25h; | 82% |
| Conditions | Yield |
|---|---|
| With 1-n-butyl-3-methylimidazolim bromide at 200 - 220℃; for 0.5h; Microwave irradiation; Inert atmosphere; | 99% |
- 204703-70-8
1-(2-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone
- 118-93-4
o-hydroxyacetophenone
| Conditions | Yield |
|---|---|
| With β‐cyclodextrin In water at 60℃; for 0.133333h; Microwave irradiation; | 98% |
| With β‐cyclodextrin In water; acetone at 60℃; for 5h; Green chemistry; | 95% |
| With ytterbium(III) chloride In neat (no solvent) at 70 - 120℃; for 0.0333333h; Microwave irradiation; Green chemistry; | 93% |
| Conditions | Yield |
|---|---|
| Stage #1: 4CH3(1-)*Zn(2+)*Li(1+); salicylic acid In tetrahydrofuran; diethyl ether; hexane at 20℃; Schlenk technique; Inert atmosphere; Stage #2: With iodine In tetrahydrofuran; diethyl ether; hexane at 20℃; Solvent; Schlenk technique; Inert atmosphere; chemoselective reaction; | 97% |
| Conditions | Yield |
|---|---|
| With β‐cyclodextrin In water at 60℃; for 0.133333h; Microwave irradiation; | 97% |
| With ytterbium(III) chloride In neat (no solvent) at 70 - 120℃; for 0.0333333h; Microwave irradiation; Green chemistry; | 92% |
| With β‐cyclodextrin In water; acetone at 60℃; for 5h; Green chemistry; | 90% |
| Conditions | Yield |
|---|---|
| With aluminum (III) chloride In dichloromethane at -5 - 25℃; | 96% |
| With hydrogen iodide at 25℃; for 24h; Inert atmosphere; | 89% |
| With 1-n-butyl-3-methylimidazolim bromide at 220℃; for 0.666667h; Inert atmosphere; Microwave irradiation; | 85% |
- 87804-23-7, 62019-23-2
2-(1-hydroxyethyl)phenol
- 118-93-4
o-hydroxyacetophenone
| Conditions | Yield |
|---|---|
| With bismuth (III) nitrate pentahydrate; cellulose supported copper(0); oxygen In acetonitrile at 60℃; for 0.5h; | 96% |
| With dihydrogen peroxide In water; acetonitrile at 25℃; for 1.25h; | 95% |
| With manganese(III) Schiff-base; dihydrogen peroxide at 20℃; for 4.5h; | 93% |
- 471-53-4Enoxolone
- 115-86-6Triphenyl phosphate
- 10039-32-4Disodium phosphate dodecahydrate
- 58-14-02,4-Pyrimidinediamine,5-(4-chlorophenyl)-6-ethyl-
- 81-88-9Xanthylium,9-(2-carboxyphenyl)-3,6-bis(diethylamino)-, chloride (1:1)
- 544-63-8Myristic acid
- 1185-57-5Ammonium ferric citrate
- 156-57-0Ethanethiol,2-amino-, hydrochloride (1:1)
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Consensus Reports
Standards and Recommendations
Specification
The o-Hydroxyacetophenone with the cas number 118-93-4, is also called (1) 1-(2-Hydroxyphenyl)ethanone ; (2) 2'-Hydroxyacetophenone ; (3) 2-Acetylphenol ; (4) 2-Hydroxyphenyl methyl ketone ; (5) Acetophenone, 2'-hydroxy- ; (6) Acetophenone, o-hydroxy- ; (7) Ethanone, 1-(2-hydroxyphenyl)- ; (8) Methyl 2-hydroxyphenyl ketone ; (9) o-Acetylphenol ; (10) o-Hydroxyacetophenone ; (11) o-Hydroxyphenyl methyl ketone so on. O-Hydroxyacetophenone belongs to the following product categories: (1)Acetophenone Series; (2)Aromatic Acetophenones & Derivatives (substituted)
Properties of o-Hydroxyacetophenone are: (1)#H bond acceptors: 2 ; (2)#H bond donors: 1 ; (3)#Freely Rotating Bonds: 2 ; (4)Polar Surface Area: 37.3 ?2 ; (5)Index of Refraction: 1.552 ; (6) Molar Refractivity: 38.16 cm3 ; (7)Molar Volume: 119.3 cm3 ; (8)Polarizability: 15.12 10-24cm3 ; (9)Surface Tension: 43.9 dyne/cm ; (10)Density: 1.14 g/cm3 ; (11)Flash Point: 87.5 °C ; (12)Enthalpy of Vaporization: 47.33 kJ/mol ; (13)Boiling Point: 218.4 °C at 760 mmHg ; (14)Vapour Pressure: 0.0856 mmHg at 25°C. O-Hydroxyacetophenone seems like clear yellow to brown liquid, and slightly soluble in water.
The o-Hydroxyacetophenone is used for intermediates in synthesis pharmaceutical special intermediate of Propafenone. When you are using o-Hydroxyacetophenone, please be cautious about it. o-Hydroxyacetophenone is not only irritating to eyes, respiratory system but also to skin. In the process of using o-Hydroxyacetophenone, please wear suitable protective clothing and gloves to protect you from harm. In case of contact with eyes, please rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure :
1. SMILES:O=C(C)c1ccccc1O
2. InChI:InChI=1/C8H8O2/c1-6(9)7-4-2-3-5-8(7)10/h2-5,10H,1H3
The o-Hydroxyacetophenone toxic data can be showed in the following sheet.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | National Technical Information Service. Vol. AD277-689, |