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122341-38-2

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Basic Information
CAS No.: 122341-38-2
Name: Temoporfin
Article Data: 3
Molecular Structure:
Molecular Structure of 122341-38-2 (Temoporfin)
Formula: C44H32N4O4
Molecular Weight: 680.762
Synonyms: 3,3',3'',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol;5,10,15,20-Tetra(m-hydroxyphenyl)chlorin;5,10,15,20-Tetrakis(m-hydroxyphenyl)chlorin;8-Dihydroporphyrin-5;EF 9;Foscan;Fosgel;Foslip;Fospeg;mTHPC;
EINECS: 624-374-5
Density: 1.386 g/cm3
Melting Point: >250 °C
PSA: 137.22000
LogP: 5.91260
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Specification

The IUPAC name of Temoporfin is 3-[10,15,20-tris(3-hydroxyphenyl)-2,3,22,24-tetrahydroporphyrin-5-yl]phenol . With the CAS registry number 122341-38-2, it is also named as 3,3',3'',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol ; 3,3',3',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol ; EF9 ; Foscan ; Phenol, 3,3',3',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis- ; UNII-FU21S769PF ; meso-Tetrahydroxyphenylchlorin . The product's classification code are antineoplastic, antineoplastic agents, dermatologic agents, photosensitizing agents and radiation-sensitizing agents.

The brand name of temoporfin is Foscan which marketed in the European Union. It is a photosensitizer used in chemotherapy for the treatment of squamous cell carcinoma of the head and neck. In a murine tumor model, the distribution of temoporfin can be used as a new photosensitizer for the photodynamic therapy of cancer.