CAS No.123-30-8,4-Aminophenol Suppliers

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Basic Information

Molecular Structure:
CAS No.:	123-30-8
Name:	4-Aminophenol
Article Data:	600
Cas Database

Formula:	C₆H₇NO
Molecular Weight:	109.128
Synonyms:	Phenol,p-amino- (8CI);1-Amino-4-hydroxybenzene;4-Amino-1-hydroxybenzene;4-Hydroxy-1-aminobenzene;4-Hydroxyaniline;4-Hydroxybenzenamine;4-Hydroxyphenylamine;Activol;Azol;BASF Ursol P Base;Benzofur P;C.I. 76550;C.I. Oxidation Base 6;Certinal;Citol;Durafur Brown RB;Fouramine P;Fourrine84;Fourrine P Base;Furro P base;NSC 1545;Nako Brown R;Paranol;PelagolGrey P Base;Pelagol P Base;Renal AC;Rodinal;Tertral P Base;Unal;Ursol P;Ursol P Base;Zoba Brown P Base;p-Aminophenol;p-Hydroxyaniline;p-Hydroxyphenylamine;p-Amino phenol;4-Aminophenol, para amino phenol;4-Aminophenol;
EINECS:	204-616-2
Density:	1.21 g/cm³
Melting Point:	188 °C
Boiling Point:	281.984 °C at 760 mmHg
Flash Point:	124.34 °C
Solubility:	Water: 1.5 g/100 mL (20 °C)
Appearance:	Off white granular powder
Hazard Symbols:	Xn,N
Risk Codes:	20/22-50/53-68-40
Safety:	28-36/37-60-61-28A
Transport Information:	UN 2512 6.1/PG 3
PSA:	46.25000
LogP:	1.55560

Synthetic route

: 100-02-7
4-nitro-phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With copper(I) chloride; potassium borohydride In methanol for 0.166667h; Ambient temperature;	100%
With palladium diacetate; carbon monoxide; triphenylphosphine In water; acetic acid at 56℃; under 532 Torr; for 14h;	100%
With hydrazine hydrate In ethanol at 80℃;	100%

: 62-53-3
aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With dihydrogen peroxide In water at 20℃; for 1.66667h; Reagent/catalyst; UV-irradiation; Green chemistry; regioselective reaction;	100%
With dihydrogen peroxide; polymer 1-A In methanol for 0.05h; Ambient temperature;	4.9%
With dihydrogen peroxide; polymer 1-A In methanol for 0.05h; Product distribution; Kinetics; Ambient temperature; various catalysts were used;	4.9%

: 103-90-2
4-acetaminophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium bromide; ethylenediamine at 70℃; for 5h; Reagent/catalyst; Temperature; Microwave irradiation;	100%
With ammonium bromide; ethylenediamine at 70℃; for 5h; Microwave irradiation; Inert atmosphere; neat (no solvent);	99%
With ammonium iodide; hydrazine hydrate at 50℃; for 12h; Inert atmosphere; Sealed tube;	97%

: 54840-09-4
carbamate de methyle et de N(hydroxy-4 phenyle)

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With 3-azapentane-1,5-diamine at 130℃; for 12h; Sealed tube;	99%

: 24541-43-3
4-azidophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol at 20℃; chemoselective reaction;	98%
With aluminium(III) iodide In benzene for 0.166667h; Reduction; Heating;	93%
With gallium(III) triflate; potassium iodide In acetonitrile at 60℃; for 1h; Inert atmosphere; Green chemistry; chemoselective reaction;	93%

: 36309-42-9
4-(trimethylsilyloxy)aniline

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0666667h; Green chemistry;	98%
With nano magnetic sulfated zirconia (Fe3O4 at ZrO2/SO42-) In neat (no solvent) at 20℃; for 0.25h; Green chemistry;	83%
With Kaolinitic clay; water for 0.0416667h; Irradiation; microwave;	63%

: 54840-15-2
4-N-tert-butoxycarbonylaminophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With water at 100℃; for 2h; Inert atmosphere;	97%
With water at 150℃; for 2h; Subcritical conditions;	95%
HY-Zeolite In dichloromethane for 2h; Heating;	92%
With 3-butyl-l-methyl-1H-imidazol-3-iumtrifloroacetate In 1,4-dioxane; water at 70 - 72℃; for 2h;	82%
With H-β zeolite In dichloromethane for 10h; Heating;	71%

: 106-41-2
4-bromo-phenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide at 20℃; for 10h; Catalytic behavior;	96%
With ammonia; triethylamine In water at 20℃; for 8h;	95%
With ammonium hydroxide at 20℃; for 12h; Catalytic behavior;	94%

: 2050-16-0
4,4'-dihydroxyazobenzene

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With zinc In methanol at 25℃; for 0.166667h; Inert atmosphere;	96%
With magnesium In methanol at 25℃; for 0.2h; Inert atmosphere;	95%
With sodium dithionite; water In dimethyl sulfoxide at 20℃; pH=7.4; Kinetics; phosphate buffer;
With hydrogenchloride; tin(ll) chloride
With sodium hydroxide; zinc

: 540-38-5
4-Iodophenol

: 123-30-8
4-amino-phenol

Conditions

Conditions	Yield
With ammonium hydroxide In water at 20℃; for 9h; Green chemistry;	95%
With copper(l) iodide; 2-carboxyquinoline N-oxide; potassium carbonate; ammonium hydroxide In dimethyl sulfoxide at 50℃; for 23h; Inert atmosphere;	90%
With copper(I) oxide; ammonium hydroxide; potassium carbonate at 140℃; for 13h; Inert atmosphere;	80%
With copper(l) iodide; ascorbic acid In ammonia at 25℃; for 18h; liquid NH3;	57%

Raw Materials

540-37-4

71-36-3

1568-66-7

106-50-3

932-98-9

Downstream Products

767-00-0

119-34-6

2724-85-8

101-83-7

637-89-8

65646-68-6

Total:172 Page 1 of 5 1 2 3 4 5 Next>>

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Consensus Reports

Related aminophenols 2-Aminophenol 3-Aminophenol
Related compounds Aniline Phenol

Specification

The 4-Aminophenol, with the CAS registry number 123-30-8, is also known as 4-Amino-1-hydroxybenzene; 4-Hydroxyaniline.It belongs to the product categories of Metabolites & Impurities;Building Blocks;C6 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols. This chemical's molecular formula is C₆H₇NO and molecular weight is 109.13. Its EINECS number is 204-616-2. What's more,Its systematic name is 4-Aminophenol. 4-Aminophenol may discolor on exposure to air and light.. It is not compatible with strong oxidizing agents, acids, bases, acid chlorides, acid anhydrides, chloroformates, and you must not take it with incompatible materials, light, exposure to a. And also prevent it to broken down into hazardous decomposition products: Nitrogen oxides, carbon monoxide, carbon dioxide.

Physical properties about 4-Aminophenol are: (1)ACD/LogP: 0.013; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.20; (4)ACD/LogD (pH 7.4): 0.01; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 14.99; (8)ACD/KOC (pH 7.4): 23.99; (9)#H bond acceptors: 2; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.637; (13)Molar Refractivity: 32.371 cm3; (14)Molar Volume: 90.144 cm3; (15)Polarizability: 12.833 10-24cm3 ; (16)Surface Tension: 57.4010009765625 dyne/cm; (17)Density: 1.211 g/cm3; (18)Flash Point: 124.34 °C; (19)Enthalpy of Vaporization: 54.173 kJ/mol; (20)Boiling Point: 281.984 °C at 760 mmHg; (21)Vapour Pressure: 0.0020000000949949 mmHg at 25°C.

The 4-Aminophenol is Limited evidence of a carcinogenic effect ,harmful by inhalation and if swallowed and Possible risk of irreversible effects.When you use it,wear suitable protective clothing and gloves.After contact with skin, wash immediately with plenty of water (to be specified by the manufacturer) .The 4-Aminophenol is very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Avoid release to the environment. Refer to special instructions safety data sheet,And this material and/or its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES:c1cc(ccc1N)O;
(2)Std. InChI:InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2;
(3)Std. InChIKey:PLIKAWJENQZMHA-UHFFFAOYSA-N.

The toxicity data of 4-Aminophenol as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	56200ug/kg (56.2mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat	LDLo	subcutaneous	37mg/kg (37mg/kg)		Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
cat	LDLo	subcutaneous	37mg/kg (37mg/kg)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
guinea pig	LDLo	subcutaneous	1500mg/kg (1500mg/kg)		Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 35, Pg. 401, 1895.
mammal (species unspecified)	LD50	oral	1530mg/kg (1530mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	skin	6400mg/kg (6400mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mammal (species unspecified)	LD50	unreported	563mg/kg (563mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(9), Pg. 19, 1983.
mouse	LD50	unreported	750mg/kg (750mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.
mouse	LDLo	intraperitoneal	100mg/kg (100mg/kg)		Revue Belge de Pathologie et de Medecine Experimentale. Vol. 22, Pg. 1, 1952.
mouse	LDLo	subcutaneous	470mg/kg (470mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 188, Pg. 130, 1938.
rabbit	LD50	oral	10gm/kg (10000mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 215, 1956.
rabbit	LD50	skin	> 10gm/kg (10000mg/kg)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LC50	inhalation	> 5mg/m3/1H (5mg/m3)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	intraperitoneal	465mg/kg (465mg/kg)	BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN	Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 31, 1944.
rat	LD50	oral	375mg/kg (375mg/kg)		BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	oral	375mg/kg (375mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: MUSCLE WEAKNESS	BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 29-4/1973,
rat	LD50	unreported	675mg/kg (675mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(3), Pg. 4, 1985.