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124-68-5

Basic Information
CAS No.: 124-68-5
Name: 1-Propanol,2-amino-2-methyl-
Molecular Structure:
Molecular Structure of 124-68-5 (1-Propanol,2-amino-2-methyl-)
Formula: C4H11NO
Molecular Weight: 89.16
Synonyms: AMP 75;AMP 90(amine);AMP Regular;Corrguard 75;Hydroxy-tert-butylamine;Isobutanol-2-amine;KV 5088;NSC 441;Pamabron;b-Aminoisobutanol;1,1-Dimethyl-2-hydroxyethylamine;2,2-Dimethylethanolamine;2-Amino-1-hydroxy-2-methylpropane;2-Amino-2,2-dimethylethanol;2-Aminoisobutanol;2-Hydroxy-1,1-dimethylethylamine;2-Hydroxymethyl-2-propylamine;2-Methyl-2-aminopropanol;AMP 100;2-Amino-2-methyl-1-propanol;
EINECS: 204-709-8
Density: 0.93 g/cm3
Melting Point: 24-28 °C(lit.)
Boiling Point: 167.2 °C at 760 mmHg
Flash Point: 67.2 °C
Solubility: water: 0.1 M at 20 °C, clear, colorless
Appearance: white crystals or viscous liquid
Hazard Symbols: IrritantXi,FlammableF
Risk Codes: 36/38-52/53
Safety: 61
Transport Information: 2735
PSA: 46.25000
LogP: 0.41630
Synthetic route

C13H17NO3

A

90-02-8

salicylaldehyde

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With hydrogenchloride In water at 80℃; for 4h;A 96%
B 80%
201230-82-2

carbon monoxide

75-31-0

isopropylamine

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With tricresyl phosphate; hydrogen; palladium diacetate In diphenylether at 140℃; under 22502.3 - 60006 Torr; Autoclave;93%
2658-24-4

2,2-dimethylaziridine

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With sulfuric acid In water at 40 - 50℃; for 1h; pH=3 - 5.4;91%
82922-13-2

2-(ethylamino)-2-methylpropanol hydrochloride

A

50-00-0

formaldehyd

B

75-04-7

ethylamine

C

124-68-5

2-Amino-2-methyl-1-propanol

D

75-07-0

acetaldehyde

E

67-64-1

acetone

Conditions
ConditionsYield
With water at 25℃; Product distribution; Mechanism; anodic oxidation, carbonate buffer, pH 10; effect of substituents investigated with different types of β-alkanolamines;A 50%
B 44%
C 14%
D 26%
E 66%
82922-13-2

2-(ethylamino)-2-methylpropanol hydrochloride

A

50-00-0

formaldehyd

B

75-04-7

ethylamine

C

124-68-5

2-Amino-2-methyl-1-propanol

D

67-64-1

acetone

Conditions
ConditionsYield
With water at 25℃; anodic oxidation, pH 10, carbonate buffer; Further byproducts given;A 50%
B 44%
C 14%
D 66%
76-39-1

2-nitro-2-methylpropanol

A

4706-13-2

N-(1-hydroxy-2-methylprop-2-yl)-hydroxylamine

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With citrate buffer; potassium chloride In ethanol at 30℃; cotrolled potential electrolysis, cathod: Hg, vs. S.C.E.;A 64%
B 25%
86241-96-5

2-methyl-3-(vinyloxy)propan-2-amine

A

N-ethylidene-2-methyl-1-vinyloxypropan-2-amine

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With mercury(II) diacetate In benzene Heating;A 3%
B n/a
76-39-1

2-nitro-2-methylpropanol

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With methanol; carbon dioxide; nickel at 70℃; under 25742.8 Torr; Hydrogenation;
With methanol; nickel at 30℃; under 25742.8 Torr; Hydrogenation;
With nickel Hydrogenation;
1113-49-1

2-methylalanine ethyl ester

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With ethanol; nickel at 100℃; under 257428 Torr; Hydrogenation;
62-57-7

2-Aminoisobutyric acid

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With tetrahydrofuran; lithium aluminium tetrahydride
With lithium aluminium tetrahydride In tetrahydrofuran
With sodium tetrahydroborate; iodine In tetrahydrofuran for 20h; Heating;
With sodium tetrahydroborate; iodine In tetrahydrofuran Reflux;
With lithium aluminium tetrahydride In tetrahydrofuran
115-11-7

isobutene

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
(i) MeCN, Cl2, (ii) H2O; Multistep reaction;
22451-34-9

2-ammonio-2-methyl-1-propanol cation

114444-46-1

C14H13NO

A

124225-44-1

1-methyl-4-(phenylacetyl)pyridinium cation

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
In water at 25℃; Equilibrium constant; Rate constant;
116221-74-0

N-chloro-2-amino-2-methylpropan-1-ol

A

124-68-5

2-Amino-2-methyl-1-propanol

B

N,N-dichloro-2-amino-2-methyl-1-propanol

Conditions
ConditionsYield
In water at 25℃; Rate constant; Thermodynamic data; E(a);

3-Amino-1-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methyl-hexan-2-ol

A

49642-07-1

statine

B

124-68-5

2-Amino-2-methyl-1-propanol

C

(3S,4R)-4-amino-3-hydroxy-6-methylheptanoic acid

Conditions
ConditionsYield
With hydrogenchloride for 1h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
87730-42-5

3-(N-succinimido)-2-propanol

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With hydrogenchloride; sodium tetrahydroborate In isopropyl alcohol
64-17-5

ethanol

1113-49-1

2-methylalanine ethyl ester

Raney nickel

Raney nickel

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
at 100℃; under 250073 Torr; Hydrogenation;
13257-67-5

2-amino-2-methylpropionic acid methyl ester

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With hydrogen; Nishimura catalyst <(45.9% Rh/19.9% Pt) oxide> In methanol at 25℃; under 75007.5 Torr;
15028-41-8

methyl 2-aminoisobutyrate hydrochloride

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With sodium tetrahydroborate; sodium hydrogencarbonate
102520-97-8

2-((tert-butyloxycarbonyl)amino)-2-methylpropan-1-ol

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane

trans-N-{4-[5-(2-Hydroxy-1,1-dimethyl-ethylamino)-pentyl]-cyclohexyl}-N-methyl-4-trifluoromethyl-benzenesulfonamide

A

trans-N-[4-(5-Bromo-pentyl)-cyclohexyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide

B

124-68-5

2-Amino-2-methyl-1-propanol

497258-63-6

(+)-pinanediol (1R)-1-acetylamino-1-[3-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)phenyl]methylboronate

A

124-68-5

2-Amino-2-methyl-1-propanol

B

(1R)-1-acetylamino-1-(3-carboxyphenyl)methylboronic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 120℃; for 1h;

(2-hydroxy-1,1-dimethyl-ethyl)-carbamic acid

A

124-38-9

carbon dioxide

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
at 125℃; Inert atmosphere; Schlenk technique;
117052-89-8

N-(1-hydroxy-2-methylpropan-2-yl)-1-naphthamide

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 135℃; for 0.166667h; Microwave irradiation;
32831-43-9

2-(hydroxymethyl)-2-methylpropylamine

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With sodium hypochlorite; sodium hydroxide In water at 0 - 70℃; for 0.333333h; Temperature; Hofmann Rearrangement;103 g

2-((E)-(1-hydroxy-2-methylpropan-2-ylimino)methyl)-6-methoxyphenol

A

148-53-8

3-methoxy-2-hydroxybenzaldehyde

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With cerium(III) nitrate hexahydrate In methanol
58004-55-0

N-(1-cyano-1-methyl-ethyl)formamide

A

682-85-9

N-(1-hydroxy-2-methylpropan-2-yl)formamide

B

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); hydrogen In 1,4-dioxane; water at 140℃; under 33753.4 Torr; for 18h; Reagent/catalyst; Pressure; Autoclave;A n/a
B 24 %Spectr.
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); hydrogen In 1,4-dioxane; water at 20 - 150℃; under 41254.1 - 101260 Torr; for 48h; Autoclave;A n/a
B 73 %Chromat.
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); water; hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In 1,4-dioxane at 150℃; under 41254.1 - 101260 Torr; for 48h; Catalytic behavior; Pressure; Reagent/catalyst; Temperature; Autoclave;A 22 %Chromat.
B 58.3 %Chromat.

C13H17NO3

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With hydrogenchloride In water at 80℃;
58004-55-0

N-(1-cyano-1-methyl-ethyl)formamide

124-68-5

2-Amino-2-methyl-1-propanol

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; water; hydrogen; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane at 140℃; under 41254.1 Torr; for 18h; Catalytic behavior; Reagent/catalyst; Pressure; Autoclave;24 %Spectr.
124-68-5

2-Amino-2-methyl-1-propanol

927-82-2

2-amino-2-methylpropyl hydrogensulfate

Conditions
ConditionsYield
With sulfuric acid In water at 50 - 120℃; for 3h; Product distribution / selectivity;100%
With chlorosulfonic acid In diethyl ether at 0℃;96%
With sulfuric acid In water at 150 - 170℃; for 4h;94%
1121-60-4

pyridine-2-carbaldehyde

124-68-5

2-Amino-2-methyl-1-propanol

134777-99-4

4,4-dimethyl-2-pyridin-2-yl-1,3-oxazolidine

Conditions
ConditionsYield
In ethanol for 2h; Ambient temperature;100%
In ethanol at 20℃; for 3h;94%
872-85-5

pyridine-4-carbaldehyde

124-68-5

2-Amino-2-methyl-1-propanol

134778-11-3

4-(4,4-Dimethyl-oxazolidin-2-yl)-pyridine

Conditions
ConditionsYield
In ethanol for 2h; Ambient temperature;100%
500-22-1

3-pyridinecarboxaldehyde

124-68-5

2-Amino-2-methyl-1-propanol

134778-05-5

3-(4,4-Dimethyl-oxazolidin-2-yl)-pyridine

Conditions
ConditionsYield
In ethanol for 2h; Ambient temperature;100%
93-89-0

benzoic acid ethyl ester

124-68-5

2-Amino-2-methyl-1-propanol

19312-05-1

N-(2-hydroxyl-1,1-dimethylethyl) benzamide

Conditions
ConditionsYield
Stage #1: 2-Amino-2-methyl-1-propanol With n-butyllithium; lanthanum(III) chloride In 1,2-dichloro-ethane at 0℃; Metallation; after the reagent addition stirring for 15 min at this temperature under nitrogen, than warming to reflux;
Stage #2: benzoic acid ethyl ester for 1h; Amidation; reflux;
100%
With sodium hydride 1.) toluene, RT, 1 h, 2.) toluene, 30 min; Yield given. Multistep reaction;
With n-butyllithium; lanthanum(lll) triflate 1) toluene, 0 deg C, 15 min then 0 to 100 deg C, 2) toluene, reflux, 12 h; Yield given. Multistep reaction;
24424-99-5

di-tert-butyl dicarbonate

124-68-5

2-Amino-2-methyl-1-propanol

102520-97-8

2-((tert-butyloxycarbonyl)amino)-2-methylpropan-1-ol

Conditions
ConditionsYield
In acetonitrile at 20℃; Condensation;100%
With triethylamine In dichloromethane at 20℃; for 2.83333h;100%
Stage #1: di-tert-butyl dicarbonate With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: 2-Amino-2-methyl-1-propanol In dichloromethane at 20℃; for 10h;
99%
96227-40-6

5-methoxy-3-methylbenzoic acid chloride

124-68-5

2-Amino-2-methyl-1-propanol

N-(2-Hydroxy-1,1-dimethyl-ethyl)-3-methoxy-5-methyl-benzamide

Conditions
ConditionsYield
In dichloromethane at 25℃; for 24h;100%
124-68-5

2-Amino-2-methyl-1-propanol

933-88-0

ortho-toluoyl chloride

95217-40-6

N-(1-hydroxy-2-methylpropan-2-yl)-2-methylbenzamide

Conditions
ConditionsYield
In dichloromethane at 0℃; for 0.5h;100%
With triethylamine In dichloromethane at 0℃;
With triethylamine In dichloromethane at 0℃; for 3h; Inert atmosphere;
123-19-3

4-heptanone

124-68-5

2-Amino-2-methyl-1-propanol

4,4-dimethyl-2,2-dipropyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
110-43-0

n-pentyl methyl ketone

124-68-5

2-Amino-2-methyl-1-propanol

51805-99-3

2,4,4-trimethyl-2-pentyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
502-56-7

5-Nonanone

124-68-5

2-Amino-2-methyl-1-propanol

174153-08-3

2,2-dibutyl-4,4-dimethyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
821-55-6

2-Nonanone

124-68-5

2-Amino-2-methyl-1-propanol

2-heptyl-2,4,4-trimethyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
693-54-9

Decan-2-one

124-68-5

2-Amino-2-methyl-1-propanol

2,4,4-trimethyl-2-octyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
927-49-1

dipentyl ketone

124-68-5

2-Amino-2-methyl-1-propanol

174153-09-4

4,4-dimethyl-2,2-dipentyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
112-12-9

methyl nonyl ketone

124-68-5

2-Amino-2-methyl-1-propanol

69184-35-6

2,4,4-trimethyl-2-nonyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
504-57-4

10-Nonadecanon

124-68-5

2-Amino-2-methyl-1-propanol

174153-10-7

4,4-dimethyl-2,2-dinonyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
124-68-5

2-Amino-2-methyl-1-propanol

111-13-7

hexyl-methyl-ketone

2-hexyl-2,4,4-trimethyloxazolidine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene Heating;100%
7169-12-2

2,3-dimethoxyterephthalic acid chloride

124-68-5

2-Amino-2-methyl-1-propanol

179693-92-6

N,N'-bis(2-hydroxy-1,1-dimethylethyl)-2,3-dimethoxyterephthalamide

Conditions
ConditionsYield
In dichloromethane at 20℃; for 2h;100%
In dichloromethane; water6.27 g (100%)
69146-58-3

2,3-bis(benzyloxy)benzoyl chloride

124-68-5

2-Amino-2-methyl-1-propanol

437613-96-2

2,3-dibenzyloxy-N-(2-hydroxy-1,1-dimethylethyl)benzamide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 6.5h;100%
14562-10-8

2-hydroxy-3-phenylbenzaldehyde

124-68-5

2-Amino-2-methyl-1-propanol

3-[(2-hydroxy-1,1-dimethylethylimino)methyl]biphenyl-2-ol

Conditions
ConditionsYield
for 1h; Heating;100%
124-68-5

2-Amino-2-methyl-1-propanol

156660-22-9

2,2'-dihydroxybiphenyl-3-carboxaldehyde

3-[(2-hydroxy-1,1-dimethylethylimino)methyl]biphenyl-2,2'-diol

Conditions
ConditionsYield
for 1h; Heating;100%
108-24-7

acetic anhydride

124-68-5

2-Amino-2-methyl-1-propanol

1569-96-6

N-(1-hydroxy-2-methylpropan-2-yl)acetamide

Conditions
ConditionsYield
Stage #1: acetic anhydride With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: 2-Amino-2-methyl-1-propanol In dichloromethane at 20℃; for 0.5h;
100%
Stage #1: acetic anhydride; 2-Amino-2-methyl-1-propanol In ethyl acetate at 20℃; for 18h; Inert atmosphere;
Stage #2: With potassium carbonate In ethyl acetate at 20℃; Inert atmosphere; chemoselective reaction;
98%
With Methylenediphosphonic acid at 20℃; for 1h; neat (no solvent); chemoselective reaction;95%
With sodium hydrogencarbonate In water at 20℃; for 16h;
With triethylamine In chloroform at 20℃; for 24h; Temperature; chemoselective reaction;99 %Spectr.
1538-75-6

2,2-dimethylpropanoic anhydride

124-68-5

2-Amino-2-methyl-1-propanol

848598-54-9

N-(2-hydroxy-1,1-dimethylethyl)-2,2-dimethylpropionamide

Conditions
ConditionsYield
Stage #1: 2,2-dimethylpropanoic anhydride With molybdenium(VI) dioxodichloride In dichloromethane at 20℃; for 0.5h;
Stage #2: 2-Amino-2-methyl-1-propanol In dichloromethane at 20℃; for 1h;
100%
98-88-4

benzoyl chloride

124-68-5

2-Amino-2-methyl-1-propanol

19312-06-2

4,5-dihydro-4,4-dimethyl-2-phenoxazole

Conditions
ConditionsYield
Stage #1: benzoyl chloride; 2-Amino-2-methyl-1-propanol In dichloromethane at 20℃; for 18h;
Stage #2: With thionyl chloride In dichloromethane Further stages.;
100%
Stage #1: benzoyl chloride; 2-Amino-2-methyl-1-propanol With triethylamine In dichloromethane at 0 - 20℃; for 10h;
Stage #2: With thionyl chloride In chloroform at 0 - 20℃; for 24h;
Stage #3: With sodium hydroxide In methanol at 0 - 20℃; for 12h;
92%
864296-43-5

3-methyl-4-isocyanato-benzoic acid methyl ester

124-68-5

2-Amino-2-methyl-1-propanol

864296-97-9

4-(3-[1,1-dimethyl-2-hydroxy-ethyl]-ureido)-3-methyl-benzoic acid methyl ester

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 2h;100%
In tetrahydrofuran at 20℃; for 2h;
860035-10-5

1-[[[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl]oxy]ethyl 2-methylpropanoate

124-68-5

2-Amino-2-methyl-1-propanol

1131570-15-4

[N-(2-hydroxy-tert-butyl)carbamoyloxy]ethyl 2-methylpropanoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile at 20℃; for 12h;100%
124-68-5

2-Amino-2-methyl-1-propanol

609-08-5

Diethyl methylmalonate

N,N'-bis(1-hydroxy-2-methylpropan-2-yl)-2-methylmalonamide

Conditions
ConditionsYield
With sodium hydride In mineral oil at 160℃; Inert atmosphere;100%
With sodium hydride at 140℃; for 4h; Inert atmosphere;95%
124-68-5

2-Amino-2-methyl-1-propanol

83-13-6

diethyl 2-phenylmalonate

N,N'-bis(1-hydroxy-2-methylpropan-2-yl)-2-phenylmalonamide

Conditions
ConditionsYield
With sodium hydride In mineral oil at 160℃; Inert atmosphere;100%
78775-72-1

2-tert-butylmalonyl dichloride

124-68-5

2-Amino-2-methyl-1-propanol

2-tert-butyl-N,N'-bis(1-hydroxy-2-methylpropan-2-yl)malonamide

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;100%
124-68-5

2-Amino-2-methyl-1-propanol

105-53-3

diethyl malonate

N,N'-bis(1-hydroxy-2-methylpropan-2-yl)malonamide

Conditions
ConditionsYield
With sodium hydride In mineral oil at 160℃; Inert atmosphere;100%
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  • High quality 2-Amino-2-Methyl-1-Propanol with high purity

  • Casno:

    124-68-5

    High quality 2-Amino-2-Methyl-1-Propanol with high purity

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    124-68-5

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  • 2-Amino-2-methyl-1-propanol

  • Casno:

    124-68-5

    2-Amino-2-methyl-1-propanol

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  • 1-Propanol,2-amino-2-methyl-

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    1-Propanol,2-amino-2-methyl-

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  • 2-Amino-2-methyl-1-propanolCAS NO.: 124-68-5

  • Casno:

    124-68-5

    2-Amino-2-methyl-1-propanolCAS NO.: 124-68-5

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History

2-AMINO-2-METHYL-1-PROPANOL(AMP) was collected on the same media used in OSHA Method 60, for diethylene triamine, so those extraction and analytical parameters were used as a starting point for AMP. The AMP was found to readily derivatize with the NITC to form a stable derivative. The samples were extracted with N,N-dimethylformamide (DMF), with a desorption efficiency mean of 100% for the concentration range of 224 to 11.2 μg/tube. The storage study showed no loss for samples stored for up to 14 days under both refrigerated and ambient conditions.

Analytical Methods

Partially evaluated method. This method has been subjected to established evaluation procedures of the Solvents Branch and is presented for information and trial use.

Specification

The CAS register number of 2-Amino-2-methyl-1-propanol is 124-68-5. It also can be called as 1-Propanol, 2-amino-2-methyl- and the IUPAC name about this chemical is 2-amino-2-methylpropan-1-ol. The molecular formula about this chemical is C4H11NO and the molecular weight is 89.14. It belongs to the following product categories, such as Industrial/Fine Chemicals; Chemical Amines; Aliphatics; Amines and so on. This chemical is stable and combustible. It incompatibles with strong oxidizing agents and it may present an explosion hazard if heated. This chemical can be used for the preparation of buffer solutions, suitable for the determination of alkaline phosphatase.

Physical properties about 2-Amino-2-methyl-1-propanol are:
(1)ACD/LogD (pH 5.5): -3.7; (2)ACD/LogD (pH 7.4): -3.1; (3)ACD/BCF (pH 5.5): 1; (4)ACD/BCF (pH 7.4): 1; (5)ACD/KOC (pH 5.5): 1; (6)ACD/KOC (pH 7.4): 1; (7)#H bond acceptors: 2; (8)#H bond donors: 3; (9)#Freely Rotating Bonds: 3; (10)Polar Surface Area: 46.25Å2; (11)Index of Refraction: 1.447; (12)Molar Refractivity: 25.61 cm3; (13)Molar Volume: 95.7 cm3; (14)Polarizability: 10.15x10-24cm3; (15)Surface Tension: 34.4 dyne/cm; (16)Enthalpy of Vaporization: 47.01 kJ/mol; (17)Boiling Point: 167.2 °C at 760 mmHg; (18)Vapour Pressure: 0.566 mmHg at 25°C.

Preparation of 2-Amino-2-methyl-1-propanol:
2-Amino-2-methyl-1-propanol can be prepared by 2-methyl-2-nitro-propan-1-ol, this reaction can also produce b-hydroxyamino-isobutyl alcohol. This reaction will need reagent citrate buffer (pH 4.2), KCl and solvent ethanol. The reaction temperature of 30 ℃. The yield is about 25%. This reaction also need cotrolled potential electrolysis, cathod: Hg, vs. S.C.E.


Uses of 2-Amino-2-methyl-1-propanol:
it can be used to produce 2-(2-hydroxy-ethylamino)-2-methyl-propan-1-o. This reaction will need reagent water.

Safety information of 2-Amino-2-methyl-1-propanol:
When you are using this chemical, please be cautious about it as the following:This chemical is irritating to eyes and skin and it is harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. When you are using it, you need avoid release to the environment. Refer to special instructions / safety data sheets.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC(C)(CO)N
(2)InChI: InChI=1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3
(3)InChIKey: CBTVGIZVANVGBH-UHFFFAOYSA-N

The toxicity data of 2-Amino-2-methyl-1-propanol is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 2150mg/kg (2150mg/kg)   Journal of the American College of Toxicology. Vol. 9(2), Pg. 203, 1990.
rabbit LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene and Toxicology. Vol. 22, Pg. 315, 1940.
rat LD50 oral 2900mg/kg (2900mg/kg)   Journal of the American College of Toxicology. Vol. 9(2), Pg. 203, 1990.