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125-04-2

Basic Information
CAS No.: 125-04-2
Name: Hydrocortisone sodium succinate
Molecular Structure:
Molecular Structure of 125-04-2 (Hydrocortisone sodium succinate)
Formula: C25H33NaO8
Molecular Weight: 502.59
Synonyms: U 4905;Cortisol,21-(hydrogen succinate), monosodium salt (8CI);Cortisol, succinate, sodium salt (6CI);A-HydroCort;Buccalsone;Corlan;Cortisol hemisuccinate sodium salt;Cortisol sodium hemisuccinate;Cortisolsodium succinate;EF-Cortelan Soluble;Emi-Corlin;Flebocortid;Hydrocortisone21-hemisuccinate sodium salt;Hydrocortisone 21-succinate sodium salt;Hydrocortisone hemisuccinate sodium salt;Hydrocortisone sodiumsuccinate;Intracort;Nordicort;Oralsone;Sodium 17-hydroxycorticosterone 21-succinate;Sodium hydrocortisone 21-hemisuccinate;Solu-Cortef;Solu-Glyc;Hydrocortisone sodium succinate;
EINECS: 204-725-5
Melting Point: 169.0-171.2°
Boiling Point: 685.5 °C at 760 mmHg
Flash Point: 231.1 °C
Solubility: H2O: 50 mg/mL
PSA: 141.03000
LogP: 0.86260
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    factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

  •  EAST CHEMSOURCES LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15053231572

    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

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  • Hydrocortisone sodium succinate

  • Casno:

    125-04-2

    Hydrocortisone sodium succinate

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 2.0-2.0

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:13958565781

    Address:Room 623 Yulan Square Bussiness Building . Jiaojiang Taizhou Zhejiang 318000 China

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  • Hydrocortisone sodium succinate

  • Casno:

    125-04-2

    Hydrocortisone sodium succinate

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

    Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, s

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    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-15965530500

    Address:shandong

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  • Hydrocortisone sodium succinate

  • Casno:

    125-04-2

    Hydrocortisone sodium succinate

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.5-1.5

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    United States  |  Contact Details

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    Tel:+1(602)7853056

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Specification

The Hydrocortisone sodium succinate, with the CAS registry number 125-04-2, is also known as 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate sodium salt. Its EINECS registry number is 204-725-5. This chemical's molecular formula is C25H33NaO8 and molecular weight is 484.51449. Its IUPAC name is called sodium 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoate. This chemical which is used as a pharmaceutical intermediate should be stored at - 20 °C. This chemical's classification codes are Drug / Therapeutic Agent; Glucocorticoid; Human Data; Reproductive Effect.

Physical properties of Hydrocortisone sodium succinate are: (1)ACD/LogP: 2.13; (2)#H bond acceptors: 8; (3)#H bond donors: 3; (4)#Freely Rotating Bonds: 9; (5)Flash Point: 231.1 °C; (6)Enthalpy of Vaporization: 114.97 kJ/mol; (7)Boiling Point: 685.5 °C at 760 mmHg; (8)Vapour Pressure: 9.36E-22 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].[O-]C(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@H]4[C@H]([C@@H](O)C[C@]12C)[C@@]3(/C(=C\C(=O)CC3)CC4)C
(2)InChI: InChI=1/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
(3)InChIKey: HHZQLQREDATOBM-HVZBPSDKBG

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man LDLo intravenous 1429ug/kg (1.429mg/kg) CARDIAC: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Medical Journal of Australia. Vol. 154, Pg. 782, 1991.
man TDLo intravenous 2857ug/kg (2.857mg/kg) LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: OXIDANT RELATED (GPD DEFICIENT) ANEMIA
Medical Journal of Australia. Vol. 154, Pg. 210, 1991.
mouse LD50 intraperitoneal 1050mg/kg (1050mg/kg)   Drugs in Japan Vol. 6, Pg. 625, 1982.
rat LD50 intraperitoneal 1320mg/kg (1320mg/kg)   Drugs in Japan Vol. 6, Pg. 625, 1982.