Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 129453 > 

129453-61-8

Basic Information
CAS No.: 129453-61-8
Name: Fulvestrant
Molecular Structure:
Molecular Structure of 129453-61-8 (Fulvestrant)
Formula: C32H47F5O3S
Molecular Weight: 606.77
Synonyms: Faslodex;Estra-1,3,5(10)-triene-3,17-diol,7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7a,17b)-;ICI 182780;ZD 182780;ZD 9238;ZM 182780;
EINECS: 642-998-6
Density: 1.201 g/cm3
Melting Point: 104-106°C
Boiling Point: 674.8 °C at 760 mmHg
Flash Point: 361.9 °C
Solubility:
Appearance: white powder
Hazard Symbols:
Risk Codes:
Safety:
Transport Information:
PSA: 76.74000
LogP: 9.54830
Synthetic route
153004-31-0

(+)-(7α)-[9-(4,4,5,5,5-pentafluoropentylsulfanyl)nonyl]estra-1,3,5(10)-triene-3,17β-diol

129453-61-8

fulvestrant

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid In water; ethyl acetate at 40℃; for 4h; Inert atmosphere; Schlenk technique;95%
Stage #1: (+)-(7α)-[9-(4,4,5,5,5-pentafluoropentylsulfanyl)nonyl]estra-1,3,5(10)-triene-3,17β-diol With β‐cyclodextrin In water; acetone at 20 - 60℃; for 0.5h;
Stage #2: With N-Bromosuccinimide In water; acetone at 40℃; for 10h; Temperature;
87%
With dihydrogen peroxide; acetic acid In water; ethyl acetate for 6 - 8h;85%

7β-[9-(4,4,5,5,5-pentafluoropentylsulfanyl)nonyl]estra-1,3,5-trien-3,17β-diol

129453-61-8

fulvestrant

Conditions
ConditionsYield
With dihydrogen peroxide; acetic acid In ethyl acetate82%
1221256-46-7

(7R,13S)-3-methoxy-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

129453-61-8

fulvestrant

Conditions
ConditionsYield
With aluminum (III) chloride; thiourea In dichloromethane at 20 - 55℃; Product distribution / selectivity;32%
261506-24-5

ICI 182,780-17β-acetate

129453-61-8

fulvestrant

Conditions
ConditionsYield
With methanol; potassium hydroxide at 20℃; for 3h; Product distribution / selectivity;

7-[9-(4,4,5,5,5-pentafluoropentylsulfanyl)nonyl]estra-1,3,5-trien-3,17β-diol

129453-61-8

fulvestrant

Conditions
ConditionsYield
With dihydrogen peroxide In water; acetic acid; ethyl acetate at 23℃; for 8h; Large scale reaction;88.4 kg
148043-73-6

4,4,5,5,5-pentafluorpentan-1-ol

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: triethylamine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
2: isopropyl alcohol / 10 h / Reflux; Inert atmosphere
3: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
4: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
5: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme
Multi-step reaction with 4 steps
1.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 17 h / 0 - 20 °C
2.1: potassium tert-butylate / tetrahydrofuran; methanol / 70 °C
3.1: hydrogenchloride / dichloromethane; methanol; water / 1 h
3.2: Reflux
4.1: acetic acid; dihydrogen peroxide / water; ethyl acetate
View Scheme
Multi-step reaction with 4 steps
1: triethylamine; dmap / dichloromethane / 1 h / -10 °C
2: ethanol / 6 h / 65 °C
3: N,N-dimethyl-formamide / 20 °C
4: acetic acid; dihydrogen peroxide / ethyl acetate
View Scheme
252947-01-6

1-methanesulfonyloxy-4,4,5,5,5-pentafluoropentane

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: isopropyl alcohol / 10 h / Reflux; Inert atmosphere
2: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
3: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
4: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme
Multi-step reaction with 3 steps
1: ethanol / Reflux
2: sodium hydroxide / water; methanol / 24 h / Inert atmosphere; Reflux
3: sodium periodate / water; methanol / 24 h / 20 °C / Cooling with ice
View Scheme
434-22-0

19-nortestosterone

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: potassium acetate; oxygen / N,N-dimethyl-formamide / 12 h / 20 - 120 °C / 6000.6 Torr / Autoclave
2.1: trichlorophosphate / dichloromethane / 4 h / 35 °C
3.1: potassium tert-butylate / toluene / 1 h / 20 - 50 °C
3.2: 3 h / 10 - 100 °C
4.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 4 h / 0 - 25 °C
5.1: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
6.1: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
7.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme
Multi-step reaction with 7 steps
1.1: toluene-4-sulfonic acid / 1 h / Reflux
2.1: N-Bromosuccinimide / N,N-dimethyl-formamide; water / 1.25 h / 0 - 7 °C / Inert atmosphere
2.2: 2 h / 0 °C / Reflux; Inert atmosphere
3.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
3.2: 0.5 h / -20 - 20 °C
4.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
5.1: water; sodium hydroxide / methanol / 5 h / 20 °C
6.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
7.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 7 steps
1.1: toluene-4-sulfonic acid / 1 h / Reflux
2.1: N-Bromosuccinimide / N,N-dimethyl-formamide; water / 1.25 h / 0 - 7 °C / Inert atmosphere
2.2: 2 h / 0 °C / Reflux; Inert atmosphere
3.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
3.2: 0.5 h / -20 - 20 °C
4.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
5.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
6.1: water; sodium hydroxide / methanol / 5 h / 20 °C
7.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
571-92-6

6-ketoestradiol

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: trichlorophosphate / dichloromethane / 4 h / 35 °C
2.1: potassium tert-butylate / toluene / 1 h / 20 - 50 °C
2.2: 3 h / 10 - 100 °C
3.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 4 h / 0 - 25 °C
4.1: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
5.1: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme

(8R,9S,13S,14S,17S)-3,17-Bis-(1-methoxy-1-methyl-ethoxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-cyclopenta[a]phenanthren-6-one

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / toluene / 1 h / 20 - 50 °C
1.2: 3 h / 10 - 100 °C
2.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 4 h / 0 - 25 °C
3.1: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
4.1: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme

C35H55BrO5

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 4 h / 0 - 25 °C
2: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
3: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
4: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme

C35H57BrO4

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
2: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme

C40H63F5O4S

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme

carbamimidothioic acid 4,4,5,5,5-pentafluoropentyl mesylate ester

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / acetonitrile; triethylamine; water / 3 h / 70 °C
2: sodium hydrogensulfate monohydrate / dichloromethane; water / 3 h / Reflux
3: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 0 - 5 °C
View Scheme
875573-66-3

(+)-(7α)-[9-bromononyl]estra-1,3,5(10)-triene-3-ol-17β-yl acetate

148757-88-4

4,4,5,5,5-pentafluoro-1-pentanethiol

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol / 2 h / 40 °C / Inert atmosphere; Schlenk technique
2: dihydrogen peroxide; acetic acid / water; ethyl acetate / 4 h / 40 °C / Inert atmosphere; Schlenk technique
View Scheme
160598-75-4

1-(acetylsulfanyl)-4,4,5,5,5-pentafluoropentane

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium hydroxide / methanol / 0.33 h / 20 °C / Inert atmosphere; Schlenk technique
2: methanol / 2 h / 40 °C / Inert atmosphere; Schlenk technique
3: dihydrogen peroxide; acetic acid / water; ethyl acetate / 4 h / 40 °C / Inert atmosphere; Schlenk technique
View Scheme
89359-54-6

9-bromo-1-nonene

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Schwartz's reagent / dichloromethane / 0.33 h / 20 °C / Inert atmosphere; Schlenk technique
1.2: 0.17 h / 20 °C / Inert atmosphere; Schlenk technique
1.3: 20 °C / Inert atmosphere; Schlenk technique
2.1: lithium bromide; copper(ll) bromide / acetonitrile / 2 h / 20 °C / Inert atmosphere; Schlenk technique
3.1: methanol / 2 h / 40 °C / Inert atmosphere; Schlenk technique
4.1: dihydrogen peroxide; acetic acid / water; ethyl acetate / 4 h / 40 °C / Inert atmosphere; Schlenk technique
View Scheme
2590-41-2

6-dehydro-19-nortestosterone acetate

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: Schwartz's reagent / dichloromethane / 0.33 h / 20 °C / Inert atmosphere; Schlenk technique
1.2: 0.17 h / 20 °C / Inert atmosphere; Schlenk technique
1.3: 20 °C / Inert atmosphere; Schlenk technique
2.1: lithium bromide; copper(ll) bromide / acetonitrile / 2 h / 20 °C / Inert atmosphere; Schlenk technique
3.1: methanol / 2 h / 40 °C / Inert atmosphere; Schlenk technique
4.1: dihydrogen peroxide; acetic acid / water; ethyl acetate / 4 h / 40 °C / Inert atmosphere; Schlenk technique
View Scheme
Multi-step reaction with 5 steps
1.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
1.2: 0.5 h / -20 - 20 °C
2.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
3.1: water; sodium hydroxide / methanol / 5 h / 20 °C
4.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
5.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 5 steps
1.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
1.2: 0.5 h / -20 - 20 °C
2.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
3.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
4.1: water; sodium hydroxide / methanol / 5 h / 20 °C
5.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
875573-63-0

(+)-3-oxo-(7α)-[9-bromononyl]estr-4-en-17β-ylacetate

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: lithium bromide; copper(ll) bromide / acetonitrile / 2 h / 20 °C / Inert atmosphere; Schlenk technique
2: methanol / 2 h / 40 °C / Inert atmosphere; Schlenk technique
3: dihydrogen peroxide; acetic acid / water; ethyl acetate / 4 h / 40 °C / Inert atmosphere; Schlenk technique
View Scheme
Multi-step reaction with 4 steps
1: copper(ll) bromide; lithium bromide / acetonitrile / 3 h / 20 °C / Large scale
2: hydrogen bromide / methanol / 3 h / Reflux; Large scale
3: sodium hydroxide / N,N-dimethyl-formamide; water / 1.5 h / 0 - 15 °C / Large scale
4: acetic acid; dihydrogen peroxide / ethyl acetate / 8 h / 20 - 30 °C / Large scale
View Scheme

C37H55BrO5

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium tert-butylate / tetrahydrofuran; methanol / 70 °C
2.1: hydrogenchloride / dichloromethane; methanol; water / 1 h
2.2: Reflux
3.1: acetic acid; dihydrogen peroxide / water; ethyl acetate
View Scheme
862700-61-6

thiobenzoic acid S-(4,4,5,5,5-pentafluoro-pentyl)ester

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium tert-butylate / tetrahydrofuran; methanol / 70 °C
2.1: hydrogenchloride / dichloromethane; methanol; water / 1 h
2.2: Reflux
3.1: acetic acid; dihydrogen peroxide / water; ethyl acetate
View Scheme
122566-22-7

(8R,9S,13S,14S,17S)-13-Methyl-3,17-bis-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-ol

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: pyridine; Dess-Martin periodane / dichloromethane / 1 h / 20 °C
2.1: triethyl borane; potassium tert-butylate / toluene; tetrahydrofuran / 0.17 h / 110 °C
2.2: Reflux
3.1: potassium tert-butylate / tetrahydrofuran; methanol / 70 °C
4.1: hydrogenchloride / dichloromethane; methanol; water / 1 h
4.2: Reflux
5.1: acetic acid; dihydrogen peroxide / water; ethyl acetate
View Scheme
53573-82-3

3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene-6-one

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethyl borane; potassium tert-butylate / toluene; tetrahydrofuran / 0.17 h / 110 °C
1.2: Reflux
2.1: potassium tert-butylate / tetrahydrofuran; methanol / 70 °C
3.1: hydrogenchloride / dichloromethane; methanol; water / 1 h
3.2: Reflux
4.1: acetic acid; dihydrogen peroxide / water; ethyl acetate
View Scheme

C29H44O3

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
2: water; sodium hydroxide / methanol / 5 h / 20 °C
3: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
4: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
2: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
3: water; sodium hydroxide / methanol / 5 h / 20 °C
4: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme

C31H44O4

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; sodium hydroxide / methanol / 5 h / 20 °C
2: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
3: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 3 steps
1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
2: water; sodium hydroxide / methanol / 5 h / 20 °C
3: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme

C27H40O2

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
2: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme

C36H51F5O4S

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water; sodium hydroxide / methanol / 5 h / 20 °C
2: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: acetic acid; dihydrogen peroxide / ethyl acetate / 0 - 25 °C
2: sodium hydroxide / methanol / 25 °C
View Scheme
148757-88-4

4,4,5,5,5-pentafluoro-1-pentanethiol

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
2: water; sodium hydroxide / methanol / 5 h / 20 °C
3: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
4999-76-2

3,17β-diacetoxy-estra-3,5-diene

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: N-Bromosuccinimide / N,N-dimethyl-formamide; water / 1.25 h / 0 - 7 °C / Inert atmosphere
1.2: 2 h / 0 °C / Reflux; Inert atmosphere
2.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
2.2: 0.5 h / -20 - 20 °C
3.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
4.1: water; sodium hydroxide / methanol / 5 h / 20 °C
5.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
6.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme
Multi-step reaction with 6 steps
1.1: N-Bromosuccinimide / N,N-dimethyl-formamide; water / 1.25 h / 0 - 7 °C / Inert atmosphere
1.2: 2 h / 0 °C / Reflux; Inert atmosphere
2.1: copper(I) bromide / tetrahydrofuran / 0.75 h / -20 °C / Inert atmosphere
2.2: 0.5 h / -20 - 20 °C
3.1: copper(I) bromide; lithium bromide / acetonitrile / 24 h / 20 °C
4.1: 2,2-dimethoxy-2-phenylacetophenone / chloroform / 5 h / 20 °C / Inert atmosphere; UV-irradiation
5.1: water; sodium hydroxide / methanol / 5 h / 20 °C
6.1: acetic acid; dihydrogen peroxide / ethyl acetate / 16 h / 20 °C
View Scheme

C11H10F5NO5S

129453-61-8

fulvestrant

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethanol / 6 h / 65 °C
2: N,N-dimethyl-formamide / 20 °C
3: acetic acid; dihydrogen peroxide / ethyl acetate
View Scheme
129453-61-8

fulvestrant

109-94-4

formic acid ethyl ester

403656-82-6

ICI 182,780-17β-formate

Conditions
ConditionsYield
With toluene-4-sulfonic acid Heating;100%
98-88-4

benzoyl chloride

129453-61-8

fulvestrant

261506-25-6

ICI 182,780-3-benzoate

Conditions
ConditionsYield
With potassium hydroxide In dichloromethane at 0 - 20℃; for 2.5h; Schotten-Baumann reaction;99%
With potassium hydroxide In dichloromethane Esterification;
141-78-6

ethyl acetate

129453-61-8

fulvestrant

261506-24-5

ICI 182,780-17β-acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid for 6h; Heating;97%
129453-61-8

fulvestrant

229625-50-7

di-tert-butyl chloromethyl phosphate

di-tert-butyl ((7R,8R,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentyl sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)methyl phosphate

Conditions
ConditionsYield
Stage #1: fulvestrant With potassium tert-butylate In tetrahydrofuran at 70℃; for 0.0833333h; Inert atmosphere;
Stage #2: di-tert-butyl chloromethyl phosphate In tetrahydrofuran at 70℃;
95.38%
129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-deca hydro-6H-cyclopenta[a]phenanthren-3-yl sulfurofluoridate

Conditions
ConditionsYield
With fluorosulfonyl fluoride; triethylamine In acetonitrile at 20℃; for 1h; chemoselective reaction;90%
With fluorosulfonyl fluoride; triethylamine In dichloromethane at 20℃; for 12h; Sealed tube;72%
103366-74-1

2,3,4,6-Tetra-O-pivaloyl-α-D-glucopyranosyl trichloroacetimidate

129453-61-8

fulvestrant

C84H131F5O21S

Conditions
ConditionsYield
Stage #1: fulvestrant With boron trifluoride diethyl etherate In 1,2-dichloro-ethane at -20℃;
Stage #2: 2,3,4,6-Tetra-O-pivaloyl-α-D-glucopyranosyl trichloroacetimidate In 1,2-dichloro-ethane Further stages.;
80%
129453-61-8

fulvestrant

ICI 182,780-17-ketone

Conditions
ConditionsYield
With oxalyl dichloride; dimethyl sulfoxide; diisopropylamine In 1,2-dichloro-ethane at -70 - 20℃; Swern oxidation;65%
990-91-0

dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate

129453-61-8

fulvestrant

dibenzyl ((7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl) phosphate

Conditions
ConditionsYield
Stage #1: fulvestrant With potassium tert-butylate In tetrahydrofuran at 70℃; for 0.0833333h;
Stage #2: dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate In tetrahydrofuran at 70℃; for 18h;
62.99%
10417-94-4

all cis-5,8,11,14,17-eicosapentaenoic acid

129453-61-8

fulvestrant

C52H75F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;58%
108-30-5

succinic acid anhydride

129453-61-8

fulvestrant

4-(((7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)-4-oxobutanoic acid

Conditions
ConditionsYield
With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 50℃; for 16h;54.08%
5070-13-3

bis-(p-nitrophenyl) carbonate

13518-40-6

L-valine tert-butylester hydrochloride

129453-61-8

fulvestrant

(2S)-tert-butyl 2-(((7R,8R,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H cyclopenta[a]phenanthren-3-yloxy)carbonylamino)-3-methylbutanoate

Conditions
ConditionsYield
Stage #1: bis-(p-nitrophenyl) carbonate; L-valine tert-butylester hydrochloride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
Stage #2: fulvestrant With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃;
48.8%
1118-68-9

dimethylaminoacetic acid

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl dimethylglycinate

Conditions
ConditionsYield
Stage #1: dimethylaminoacetic acid; fulvestrant With dmap In dichloromethane at 0℃; for 0.166667h;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 16h;
46.77%
5070-13-3

bis-(p-nitrophenyl) carbonate

16874-17-2

L-phenylalanine tert-butyl ester

129453-61-8

fulvestrant

(2S)-tert-butyl 2-(((7R,8R,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-(4,4,5,5,5-pentafluoro pentylsulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yloxy)carbonylamino)-3-phenylpropanoate

Conditions
ConditionsYield
Stage #1: bis-(p-nitrophenyl) carbonate; L-phenylalanine tert-butyl ester With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
Stage #2: fulvestrant With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; Inert atmosphere;
33.96%
3235-69-6

morpholin-4-ylacetic acid

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 2-morpholinoacetate

Conditions
ConditionsYield
Stage #1: morpholin-4-ylacetic acid; fulvestrant With dmap In dichloromethane at 0℃; for 0.0833333h;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 2h;
33.07%
39539-66-7

4-methyl-piperazine-1-carbonyl chloride

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 4-methylpiperazine-1-carboxylate

Conditions
ConditionsYield
Stage #1: fulvestrant With dmap; potassium carbonate In acetonitrile at 20℃; for 0.5h;
Stage #2: 4-methyl-piperazine-1-carbonyl chloride at 0 - 20℃; for 18h;
31.46%
112-37-8

undecylenic acid

129453-61-8

fulvestrant

C43H67F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;27.7%
4497-04-5

3-morpholin-4-ylpropionic acid

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 3-morpholinopropanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 6h;26.37%
129453-61-8

fulvestrant

229625-50-7

di-tert-butyl chloromethyl phosphate

di-tert-butyl ((((7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl- 7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)oxy)methyl) phosphate

Conditions
ConditionsYield
Stage #1: fulvestrant With potassium tert-butylate In tetrahydrofuran at 70℃; for 0.25h;
Stage #2: di-tert-butyl chloromethyl phosphate In tetrahydrofuran at 70℃; for 7h;
26.14%
814-49-3

diethyl chlorophosphate

129453-61-8

fulvestrant

diethyl ((7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl) phosphate

Conditions
ConditionsYield
Stage #1: fulvestrant With tetrabutylammomium bromide; sodium hydroxide In chloroform; water at 20℃; for 0.5h;
Stage #2: diethyl chlorophosphate In chloroform; water at 20℃; for 16h;
24.5%
129453-61-8

fulvestrant

54699-92-2

(4-Methyl-piperazin-1-yl)-acetic acid

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 2-(4-methylpiperazin-1-yl)acetate

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 16h;24.37%
37386-15-5

2-(pyrrolidin-1-yl)acetic acid

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 2-(pyrrolidin-1-yl)acetate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 6h;23.24%

5,7,7-trimethyl-2-(1,3,3-trimethylbutyl)-octanoic acid

129453-61-8

fulvestrant

C50H81F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;23.2%
57-10-3

1-hexadecylcarboxylic acid

129453-61-8

fulvestrant

C48H77F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;22%
129453-61-8

fulvestrant

C43H65F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;21.5%
129453-61-8

fulvestrant

docosahexa-4,7,10,13,16,19-enoic acid

C54H77F5O4S

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 48h;21.1%
129453-61-8

fulvestrant

69-72-7

salicylic acid

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 2-hydroxybenzoate

Conditions
ConditionsYield
Stage #1: fulvestrant; salicylic acid With dmap In dichloromethane at 0℃; for 0.0833333h;
Stage #2: With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 16h;
18.92%
6300-04-5

3-dimethylaminopropionic acid

129453-61-8

fulvestrant

(7R,8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl 3-(dimethylamino)propanoate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 12h;18.62%
Raw Materials
153004-31-0
  • Display:default sort

    New supplier

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

  •  Afine Chemicals Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

       Inquiry Now

  • Fulvestrant 129453-61-8

  • Casno:

    129453-61-8

    Fulvestrant 129453-61-8

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-10.0/Kilogram

    Hanways focus on: -Pharmaceutical raw materials -Chemical raw materials -Food additives -Flavors and fragrances -Feed additives -Plant extracts -Veterinary raw materials We could supply you: -Best quality -Competitive price

    Hubei Hanways Pharmchem Co.,Limited is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. Now we

  •  HANWAYS CHEMPHARM CO.,LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18502787239(whatsapp)

    Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

       Inquiry Now

  • low price/129453-61-8/Fulvestrant

  • Casno:

    129453-61-8

    low price/129453-61-8/Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    High purity with HPLC & NMR chart 99% purity with low price in stock specilized in hard-to-find chemicals Appearance:white powder Storage:keep away from heat,sparks and flames Package:1gram/bag Application:Fulvestrant and its intermediat

    Tianyuan pharmaceutical company in Zhangjiang Eastern has built 500 square meters of pilot laboratories, equipped with two sets of 50L glass reactor, four sets of 100L double react

  •  Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-755-23284190

    Address:B302,2 unit, Jin Lian Building, No. 134 Qianjin 2 Road, Taoyuan village, Xixiang Street, Baoan,Shenzhen,China

       Inquiry Now

  • High quality Fulvestrant? supplier in China

  • Casno:

    129453-61-8

    High quality Fulvestrant? supplier in China

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional

  •  Simagchem Corporation

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592-2680277

    Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China

       Inquiry Now

  • Fulvestrantly Powder Anti Estrogen API CAS 129453-61-8 Fast Delivery

  • Casno:

    129453-61-8

    Fulvestrantly Powder Anti Estrogen API CAS 129453-61-8 Fast Delivery

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shangha

    Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd (JL Pharm) is established in 2012 at the beautiful West Lake – Hangzhou city, China. The company's main business includes R&D, Produ

  •  Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-571-85829053

    Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area

       Inquiry Now

  • 129453-61-8  Fulvestrant

  • Casno:

    129453-61-8

    129453-61-8 Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 40.0-50.0/Gram

    1.good quality 1) good quality is the basic of our goal; 2) we can offer samples to be tested; 3) 98% of our products have exported to uk, usa, germany, spain, australia, middle east and many other countries. 4) Good feedback of quality from our cu

    Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermedia

  •  WUHAN MULEI NEW MATERIAL CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619831967063

    Address:Office1201#, Block C, Hanjie Headquarters International Plaza, Zhongbei Rd, Wuchang District, Wuhan

       Inquiry Now

  • fulvestrant

  • Casno:

    129453-61-8

    fulvestrant

    Min.Order: 5 Gram

    FOB Price:  USD $ 80.0-150.0/Gram

    chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

    Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of

  •  Hebei yanxi chemical co.,LTD.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-0311-66561638

    Address:Zhang zhe, guangzong county, xingtai city, hebei province

       Inquiry Now

  • Fulvestrant       --  CHemwill

  • Casno:

    129453-61-8

    Fulvestrant -- CHemwill

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.0-1.0/Metric Ton

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0/Kilogram

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,an

  •  Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:0086-317-5105699

    Address:40# Shuiyuesi Street, Cangzhou City,Hebei Province, China.

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    High quality, low price. We can provide free sample for test. After shipment, keep sample for 3 years. Packing as your request, with photo before shipment. Fast delivery, tracking number available, first-class service to customers. Facto

    Hubei Danjiangkou Danao pharmaceutical Chemical Co.,Ltd is located in famous Taoist Holy Place-Wudang Mountain. It is next to the middle origin of South-to-North Water Diversion Pr

  •  Hubei Danao Pharmaceutical Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-719-5251167

    Address:Fandan Road,Danjiangkou,Hubei

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0/Kilogram

    Product Name Fulvestrant Synonyms (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol Molecular Formula C32H47F5O3S Molecu

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

       Inquiry Now

  • 99% Fulvestrant 129453-61-8 Treatment Of Breast Cancer

  • Casno:

    129453-61-8

    99% Fulvestrant 129453-61-8 Treatment Of Breast Cancer

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8615102730682

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • TIANFU-CHEM CAS:129453-61-8 Fulvestrant

  • Casno:

    129453-61-8

    TIANFU-CHEM CAS:129453-61-8 Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Fulvestrant Basic information Product Name: Fulvestrant Synonyms: ICI 182,780;FULVESTRANT;FULVESTRANT-13C1-D2;FASLODEX;(7a,17b)-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • Pharmaceutical Intermediates CAS 129453-61-8

  • Casno:

    129453-61-8

    Pharmaceutical Intermediates CAS 129453-61-8

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    CAS 129453-61-8 MF C32H47F5O3S Purity 99%min Color White Appearance Powder Grade Pharmaceutical Grade MO

    We are Hebei miaobian Biotechnology Co., Ltd , mainly deal in pharmaceutical intermediates and various chemicals. It is with a registered capital of 3 million yuan, is one of the m

  •  Hebei miaobian Biotechnology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15032793961

    Address:Federal Business Plaza, Qiaoxi District,Shijiazhuang

       Inquiry Now

  • Manufacturer supply CAS 129453-61-8 with best quality

  • Casno:

    129453-61-8

    Manufacturer supply CAS 129453-61-8 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0/Kilogram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • BLOOM TECH Advanced API/Technology support Fulvestrant CAS 129453-61-8

  • Casno:

    129453-61-8

    MSDS/COA Download

    BLOOM TECH Advanced API/Technology support Fulvestrant CAS 129453-61-8

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Inquiry guide 1.Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you. 2.Then we will provide the professional quotation list for you, it will be including all the factors in who

    WHO WE ARE 1.We Focus on the technology of Organic Synthesis since 2008. 2.API/Pharmaceutical intermediate/Fine chemical/New material/Extraction etc. 3.Chemical reagent: Over 300,0

  •  Shaanxi BLOOM TECH Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-29-86470566

    Address:Block A of Central Mansion, No.113 of Weiyang Rd, ETDZ, Xi'an, Shaanxi 710016, China

       Inquiry Now

  • Fulvestrant good quality AOKS  Alsa Lee supplier in China

  • Casno:

    129453-61-8

    MSDS/COA Download

    Fulvestrant good quality AOKS Alsa Lee supplier in China

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Why choose us 1. Extensive expertise in API business 2. Flexible business way 3. A good troubleshooter/very positive attitude for after service 4. Stock availability 5. Strong backup of facotry: high R&D ability, favorable

    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

       Inquiry Now

  • Fulvestrant and intermediates manufacturer

  • Casno:

    129453-61-8

    MSDS/COA Download

    Fulvestrant and intermediates manufacturer

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Sr.No. TEST Specification 1 CHEMICAL NAME (7α,17β)-7-{[9-(4,4,5,5,5-Pentafluoropentyl)thio]nonyl}eatra-1,3,5(10)-triene-3,1

    HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketi

  •  Hangzhou Think Chemical Co. Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-571-89986307/81956191/81956084/81956192

    Address:Room 719 Building D Meidu Plaza 789 Moganshan Road

       Inquiry Now

  • hot sale Fulvestrant

  • Casno:

    129453-61-8

    hot sale Fulvestrant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1,In No Less five years exporting experience. 2,Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White to Off-white Crystalli

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • Muscle injection drugs Fulvestrant with CAS:129453-61-8

  • Casno:

    129453-61-8

    Muscle injection drugs Fulvestrant with CAS:129453-61-8

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 143.0-157.0/Kilogram

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

  •  Baoji Guokang Healthchem co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

       Inquiry Now

  • White pigment Fulvestrant CAS NO.129453-61-8

  • Casno:

    129453-61-8

    White pigment Fulvestrant CAS NO.129453-61-8

    Min.Order: 20 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

    Changchun Artel Import and Export Trade Co., Ltd. is located in Changchun City, Jilin Province. It is a high-tech modern private enterprise specializing in the research, developme

  •  Changchun Artel lmport and Export trade company

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0431-80543058

    Address:Dianshi Plazza,Chaoyang District

       Inquiry Now

  • Treatment of Breast Cancer 98% Fulvestrantly Powder Anti Estrogen API In Stock Fast Delivery

  • Casno:

    129453-61-8

    Treatment of Breast Cancer 98% Fulvestrantly Powder Anti Estrogen API In Stock Fast Delivery

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers

    WUHAN WONDA PHARMACEUTICAL AND CHEMICAL LIMITED is specializing in custom synthesis, manufacture and import & export of nootropics, herbal extract, OLED etc. Wuhan Wonda Pharm & Ch

  •  Wuhan Wonda Pharm Limited

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:027-84306245

    Address:Wuhan Private Science and Technology Park , Wuhan, China

       Inquiry Now

  • Fulvestrant CAS NO.129453-61-8

  • Casno:

    129453-61-8

    Fulvestrant CAS NO.129453-61-8

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Minimum Order Qty. 10 Gram

    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

  •  Jilin Tely Imp.& Exp.Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

       Inquiry Now

  • Fulvestrant 129453-61-8

  • Casno:

    129453-61-8

    Fulvestrant 129453-61-8

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 100.0-150.0/Kilogram

    Our company: Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kinds of products.

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8613397160123

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

       Inquiry Now

  • Fulvestrant CAS 129453-61-8

  • Casno:

    129453-61-8

    Fulvestrant CAS 129453-61-8

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Crovell Biotech (Hebei) Co., Ltd.(Crovell) exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, Crovell is your best choice. Our advantages: 1, High

    Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group,which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector amon

  •  Hebei Guanlang Biotechnology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+8619930503256

    Address:No.66, Yuhua West Road

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.9 years exporting experience; Mixed container, we can mix different items in one container. 2.Competitive price and quality; 3. free sample for test. after shipment, keep sample for 2 years 4.We are sincerely responsible for the"samp

    Enbridge PharmTech Co., Ltd. is an innovative company integrated with R&D, manufacturing, marketing and distribution of intermediates and fine chemicals, mainly used to pharmaceuti

  •  EnBridge PharmTech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-510-83591909

    Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China

       Inquiry Now

  • Hot selling of Anastrozole

  • Casno:

    129453-61-8

    Hot selling of Anastrozole

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 90.0-100.0/Metric Ton

    JD003 Product Name: Fulvestrant Synonyms: (7a,17b)-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol;7A,17B-[9[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFI

    Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded t

  •  Career Henan Chemical Co

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-86658258

    Address:Building 3 of Innovation Park, East District of the National University Science Park

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

    Shanghai BetterBioChem Co., Ltd. specializes in research, production of APIs, building blocks and key pharmaceutical intermediates. We provide our products from milligrams to kilog

  •  Shanghai BetterBioChem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18013506594

    Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

    J&H Chemical is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other

  •  Hangzhou J&H Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-87396432

    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

       Inquiry Now

  • Fulvestrant (ICI 182780)with factory price

  • Casno:

    129453-61-8

    Fulvestrant (ICI 182780)with factory price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization. Company has strong ability of research and development

    Wuhan Sun-shine Bio-technology Corporation Limited (Shanghai Sun-shine Chemical Technology Corporation Limited) is a high-tech enterprise engaged inR&D and sales of related compoun

  •  Wuhan Sun-shine Bio-technology Corporation Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-27-65522452

    Address:No. 388 Gaoxin Road(No. 2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC

       Inquiry Now

  • Fulvestrant 99% Manufactuered in China best quality

  • Casno:

    129453-61-8

    Fulvestrant 99% Manufactuered in China best quality

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Product Name: Fulvestrant Synonyms: (7a,17b)-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol;7A,17B-[9[(4,4,5,5,5-PENTAFLUOROPENTYL)SULFINYL]NONYL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL;(7alpha,17beta)-nonyl);estra-1

    Wuhan Zenuo Biopharmaceutical Technology Co., Ltd. is a global biopharmaceutical and chemical enterprise, mainly engaged in the customized synthesis, large-scale production and sal

  •  Wuhan Zenuo Biological Medicine Technology Co Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:(+86-27)8700-2750

    Address:Floor 19th,No.76,Longyang Road

       Inquiry Now

  • Factory Price powder 99%  Fulvestrant    CAS: 129453-61-8

  • Casno:

    129453-61-8

    Factory Price powder 99% Fulvestrant CAS: 129453-61-8

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 150.0-150.0/Kilogram

    Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countrie

    Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in carbomer, Dibenzylamine,meglumine,lead acetate and other chemical raw materials and chemical reagents research

  •  Hebei Mojin Biotechnology Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:13231137666

    Address:room 1401,A building,Enjoy city,shijiazhuang city,hebei province,China

       Inquiry Now

  • Fulvestrant  129453-61-8

  • Casno:

    129453-61-8

    Fulvestrant 129453-61-8

    Min.Order: 100 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

    Triumph International Development Limilted is engaged in the API, pharmaceutical intermediates research and developmen.Adhering to the "customer first" business philosophy,we suppl

  •  Triumph International Development Limilted

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-536-7971999

    Address:Yinhai Road,Shouguang

       Inquiry Now

  • Fulvestrant

  • Casno:

    129453-61-8

    Fulvestrant

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

  •  Shandong Hanjiang Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

       Inquiry Now

  • High Purity Fulvestrant

  • Casno:

    129453-61-8

    High Purity Fulvestrant

    Min.Order: 1 Gram

    FOB Price:  USD $ 5.0-10.0/Gram

    Strong backup of facotry: high R&D ability, favorable quality and competitive price 2. Stock avaliability 3. Flexible business way, like payment term and product delivery 4. Fast response 24*7 5. A good troubleshooter/very positive atti

    Beijing Yibai Biotechnology Co., Ltd, backed up with factory toppest support with high R&D ability, we have confidence to make you more competitive on market. Yibai is devoting fo

  •  Beijing Yibai Biotechnology Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-010-60404860

    Address:Xuhui Plaza, Shunyi district, Beijing

       Inquiry Now

  • Manufacturer supply Fulvestrant

  • Casno:

    129453-61-8

    Manufacturer supply Fulvestrant

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.High quality and competetive price 1)for prulifloxacin exported we can offer coa certificate and official invoice. 2)we are manufacturer with own lab and factory, can provide high quality products with factory price. 3)products purity is tes

    Wuhan New-Rise biochem Co.,Ltd. is a leading provider and manufacturer of pharmaceutical and chemical products. We are dedicated in providing a wide variety of quality API, pharm

  •  Wuhan New-Rise Biochem Co,. Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13667132959

    Address:Wuhan

       Inquiry Now

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Structure of Fulvestrant (CAS NO.129453-61-8):

IUPAC Name: (7R,8R,9S,13S,14S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-7,8,9,11,12,14,15,16,
17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular Formula: C32H47F5O3S
Molar Mass: 606.77  g/mol
Flash Point: 361.9 °C
Boiling Point: 674.8°C at 760 mmHg
Vapour Pressure: 3.95E-19  mmHg at 25 °C
Density: 1.201 g/cm3
Storage Temp.: 2-8 °C 
Index of Refraction: 1.521
Molar Refractivity: 154.04 cm3
Molar Volume: 505.1 cm3
Surface Tension: 41.9 dyne/cm 
XLogP3: 9.2
H-Bond Donor: 2
H-Bond Acceptor: 8
Rotatable Bond Count: 14
Tautomer Count: 9
Exact Mass: 606.316607
MonoIsotopic Mass: 606.316607
Topological Polar Surface Area: 57.5
Heavy Atom Count: 41 
Canonical SMILES: CC12CCC3C(C1CCC2O)C(CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
InChI: InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-27+,28+,29-,30+,41/m1/s1
InChIKey: VWUXBMIQPBEWFH-WCCTWKNTSA-N
Product Categories: Intermediates & Fine Chemicals; Pharmaceuticals; Nuclear Receptors

Uses

 Fulvestrant (CAS NO.129453-61-8) is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy.

Safety Profile

RTECS: KG7623000

Specification

 Fulvestrant (CAS NO.129453-61-8) is also named as 7alpha-(9-((4,4,5,5,5-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol ; CCRIS 8741 ; Faslodex ; HSDB 7658 ; ICI 182,780 ; ICI 182780 ; UNII-22X328QOC4 ; ZM 182780 . Fulvestrant (CAS NO.129453-61-8) is white powder.