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CAS No.: | 131707-25-0 |
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Name: | Arbidol |
Article Data: | 5 |
Molecular Structure: | |
Formula: | C22H25BrN2O3S |
Molecular Weight: | 477.422 |
Synonyms: | Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate;ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate; |
EINECS: | 814-571-6 |
Density: | 1.375 g/cm3 |
Boiling Point: | 591.776 °C at 760 mmHg |
Flash Point: | 311.695 °C |
Appearance: | White to off-white crystalline powder |
PSA: | 80.00000 |
LogP: | 5.17700 |
Molecular Formula: C22H25BrN2O3S
Molecular Weight: 531.89
Density: 1.37 g/cm3
Flash Point: 311.7 °C
Index of Refraction: 1.619
CAS Registry Number: 131707-25-0
Enthalpy of Vaporization: 91.52 kJ/mol
Boiling Point: 591.8 °C at 760 mmHg
Vapour Pressure: 1.34E-14 mmHg at 25°C
IUPAC: Ethyl 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate
Synonyms: Ethyl6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl. ; Arbidol ; Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate ; Intermediate:Arbidolhydrochloride
Following is the molecular structure of Arbidol (CAS NO.131707-25-0):
Clinical application of Arbidol (CAS NO.131707-25-0):
Arbidol is used primarily as an antiviral treatments for influenza. It is compared most with oseltamivir.
The drug has also been investigated as a candidate drug for treatment of hepatitis C.
Arbidol (CAS NO.131707-25-0) is an antiviral treatment for influenza infection used in Russia and China. The drug is manufactured by Moscow-based Masterlek. Its acceptance amongst the pharamecutical industry varies, although some Russian studies have shown it to be as effective as other available treatments.
Chemically, Arbidol features an indole core, functionalized at all positions but one with different substituents. The drug inhibits viral entry into target cells, and also stimulates the immune response.