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CAS No.: 131707-25-0
Name: Arbidol
Article Data: 5
Molecular Structure:
Molecular Structure of 131707-25-0 (Arbidol)
Formula: C22H25BrN2O3S
Molecular Weight: 477.422
Synonyms: Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate;ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate;
EINECS: 814-571-6
Density: 1.375 g/cm3
Boiling Point: 591.776 °C at 760 mmHg
Flash Point: 311.695 °C
Appearance: White to off-white crystalline powder
PSA: 80.00000
LogP: 5.17700
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  • Arbidol

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  • Arbidol

  • Casno:

    131707-25-0

    Arbidol

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Chemistry

Molecular Formula: C22H25BrN2O3S
Molecular Weight: 531.89
Density: 1.37 g/cm3 
Flash Point: 311.7 °C 
Index of Refraction: 1.619
CAS Registry Number: 131707-25-0
Enthalpy of Vaporization: 91.52 kJ/mol 
Boiling Point: 591.8 °C at 760 mmHg
Vapour Pressure: 1.34E-14 mmHg at 25°C 
IUPAC: Ethyl 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate
Synonyms: Ethyl6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl. ; Arbidol ; Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate ; Intermediate:Arbidolhydrochloride
Following is the molecular structure of Arbidol (CAS NO.131707-25-0):

Uses

Clinical application of Arbidol (CAS NO.131707-25-0):
Arbidol is used primarily as an antiviral treatments for influenza. It is compared most with oseltamivir.
The drug has also been investigated as a candidate drug for treatment of hepatitis C.

Specification

 Arbidol (CAS NO.131707-25-0) is an antiviral treatment for influenza infection used in Russia and China. The drug is manufactured by Moscow-based Masterlek. Its acceptance amongst the pharamecutical industry varies, although some Russian studies have shown it to be as effective as other available treatments.
Chemically, Arbidol features an indole core, functionalized at all positions but one with different substituents. The drug inhibits viral entry into target cells, and also stimulates the immune response.