CAS No.13412-64-1,Dicloxacillin sodium Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	13412-64-1
Name:	Dicloxacillin sodium

Formula:	C₁₉H₁₆Cl₂N₃NaO₅S^.H₂O
Molecular Weight:	510.33
Synonyms:	4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate, (2S,5R,6R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, monohydrate, [2S-(2a,5a,6b)]-;3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl penicillin sodium saltmonohydrate;Dichlorstapenor sodium;Dicloxacillin sodium hydrate;Dicloxacillin sodium monohydrate;Dicloxacillin sodium salt hydrate;P 1011;Sodium dicloxacillin hydrate;Sodium dicloxacillin monohydrate;
EINECS:	206-444-3
Density:	g/cm³
Melting Point:	222-225 °C
Boiling Point:	692.4 °C at 760 mmHg
Flash Point:	372.5 °C
Solubility:	Soluble in water
Appearance:	White to off-white crystalline powder
Hazard Symbols:	Xn
Risk Codes:	36/37/38-42/43
Safety:	22-26-36/37-45
PSA:	150.10000
LogP:	2.13190

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Chemistry

3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN SODIUM MONOHYDRATE's MF: C19H16Cl2N3NaO5S.H2O
3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN SODIUM MONOHYDRATE's MW: 510.32
Synonyms: dicloxacillin sodium monohydrate;Dicloxacillin Sodium; Cloxacillin Sodium

Uses

3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN SODIUM MONOHYDRATE is beta-lactamase-producing of antibiotics.

Toxicity Data With Reference

1.	orl-rat LD50:3579 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185.
2.	ipr-rat LD50:630 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 15 (1965),322.
3.	ivn-rat LD50:520 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.
4.	orl-mus LD50:4560 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.
5.	ipr-mus LD50:1000 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.
6.	scu-mus LD50:1100 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.
7.	ivn-mus LD50:875 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.
8.	ivn-rbt LD50:600 mg/kg	JJANAX Japanese Journal of Antibiotics. 21 (1968),274.

Safety Profile

Moderately toxic by ingestion, intraperitoneal, intravenous, and subcutaneous routes. An antibacterial agent. When heated to decomposition it emits very toxic fumes of Na₂O, NO_x, SO_x, and Cl^?. See also PENICILLIN; PENICILLIN compounded with CHOLINE CHLORIDE; PENICILLIN G BENETHAMINE; PENICILLIN G EPHEDRINE SALT; PENICILLIN G PROCAINE.