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13504-85-3

Basic Information
CAS No.: 13504-85-3
Name: N-Cbz-Hydroxy-L-proline
Article Data: 75
Molecular Structure:
Molecular Structure of 13504-85-3 (N-Cbz-Hydroxy-L-proline)
Formula: C13H15NO5
Molecular Weight: 265.266
Synonyms: (2S,4R)-1-(Benzyloxycarbonyl)-4-hydroxyproline;(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-benzyl ester;1-(Benzyloxycarbonyl)-trans-4-hydroxy-(S)-proline;N-(Benzyloxycarbonyl)-trans-4-Hydroxy-D-proline;N-Carbobenzoxy-4-hydroxy-L-proline;Z-Hyp-OH;1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-benzyl ester, L-trans-(6CI,8CI);
EINECS: 236-831-2
Density: 1.416 g/cm3
Melting Point: 104-107 °C
Boiling Point: 486.9 °C at 760 mmHg
Flash Point: 248.3 °C
Solubility: Slightly soluble in water.
Appearance: White fine crystalline powder
PSA: 87.07000
LogP: 0.78090
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    Product Name: N-Cbz-Hydroxy-L-proline CAS: 13504-85-3 MF: C13H15NO5 MW: 265.26 EINECS: 236-831-2 Mol File: 13504-85-3.mol N-Cbz-Hydroxy-L-proline Structure N-Cbz-Hydroxy-L-proline Chemical Properties Melting point 104-107 °

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  • Casno:

    13504-85-3

    1-[(Benzyloxy)Carbonyl]-4-Hydroxypyrrolidine-2-Carboxylic Acid

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0

    Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

    Jinhua huayi chemical co., ltd. has own manufacturers which focus on production of organic specialty products,Pharmaceuticals and its intermediates,fine chemcals of high purity.The

  •  JINHUA HUAYI CHEMICAL CO., LTD.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-579-82660891

    Address:47-204 No.288, Shida St., Wuchem Dist., Jinhua,Zhejiang, 321004 China

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  • Acmec Z-Hyp-OH 500g

  • Casno:

    13504-85-3

    Acmec Z-Hyp-OH 500g

    Min.Order: 1 bottle

    FOB Price:  USD $ 0.0-0.0

    Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

  •  Shanghai Acmec Biochemical Technology Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86--

    Address:Room 1301, No. 1, Lane 1588, South Wangyuan Road, Nanqiao Town, Fengxian District, Shanghai

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  • N-Benzyloxycarbonyl-L-Hydroproline

  • Casno:

    13504-85-3

    N-Benzyloxycarbonyl-L-Hydroproline

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

    Xiamen Aeco Chemical Industrial Co., Ltd(same as Aecochem Corp.) An ISO 9001:2015 Certified Company Your Partner in China, a Professional chemical raw material supplier, our

  •  Aecochem Corp.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592 599 8717

    Address:No 611 Sishui Road,Huli

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  • Z-L-4-trans-hydroxyproline

  • Casno:

    13504-85-3

    Z-L-4-trans-hydroxyproline

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell. https://aapep.bocsci.com/product/z-l

    BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-info

  •  BOC Sciences

    United States  |  Contact Details

    Business Type:Trading Company

    Tel:1-631-485-4226

    Address:Ramsey Road

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  • Z-Hyp-OH

  • Casno:

    13504-85-3

    Z-Hyp-OH

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Application:Intermidates

    GL Biochem (Shanghai) Ltd. founded in 1998, has become an internationally recognized biochemical manufacturing company that specializes in manufacturing and providing peptide reage

  •  GL Biochem (Shanghai) Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-21-61263310

    Address:519 Ziyue Road, Shanghai, 200241, China.

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  • N-Cbz-L-Hydroxy-L-proline

  • Casno:

    13504-85-3

    N-Cbz-L-Hydroxy-L-proline

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Fredchem focus on CRO/CMO business and its own R&D of API/Intermediates Package:Kilograms/MT Application:Pharmaceutical field Transportation:According to customer request Port:Shanghai

    Nanjing Fred Technology Co.,Ltd. is a Fine Chemicals Company, specializing in research, development, manufacture and distribute raw materials for pharmaceutical, healthcare, bioc

  •  Nanjing Fred Technology Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-84696168

    Address:Nanjing

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  • trans-N-Carbobenzoxy-4-hydroxy-L-proline

  • Casno:

    13504-85-3

    trans-N-Carbobenzoxy-4-hydroxy-L-proline

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

    Antimex Chemical Limied, was founded in 2001, we are specializing in manufacturing & researching of Active pharmaceutical Ingredients,Veterinary pharm APIs,cosmetic ingredients,and

  •  Antimex Chemical Limied

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-50563169

    Address:Room1027,No.Jinyu Road,Pudong

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  • Z-trans-4-hydroxy-L-proline

  • Casno:

    13504-85-3

    Z-trans-4-hydroxy-L-proline

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    ★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

    Hangzhou Ocean Chemical Co.ltd is a comprehensive chemical enterprise which mainly integrates R&D, production, marketing business of chemical in lab-pack, semi-bulk and bulk-quanti

  •  Hangzhou Ocean Chemical Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88025872, 28272092, 28272096

    Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China

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Specification

The IUPAC name of N-Cbz-Hydroxy-L-proline is 4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid . With the CAS registry number 13504-85-3, it is also named as 1-Benzyl hydrogen (2S-trans)-4-hydroxypyrrolidine-1,2-dicarboxylate ; (4R)-1-[(Benzyloxy)carbonyl]-4-hydroxy-L-proline ; 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(phenylmethyl) ester, (2S,4R)- ; Z-Hyp-OH ; Z-L-4-Hydroxyproline .

The N-Cbz-Hydroxy-L-proline is white fine crystalline powder which should be stored at RT.. The product's categories are hydroxyproline [Hyp], unusual amino acids and Z-amino acid series. This product can be used as pharmaceutical intermediates. It also can be used to prepare other chemicals.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.10 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): -1.82 ; (4)ACD/LogD (pH 7.4): -3.48 ; (5)ACD/BCF (pH 5.5): 1 ; (6)ACD/BCF (pH 7.4): 1 ; (7)ACD/KOC (pH 5.5): 1 ; (8)ACD/KOC (pH 7.4): 1 ; (9)#H bond acceptors: 6 ; (10)#H bond donors: 2 ; (11)#Freely Rotating Bonds: 5 ; (12)Index of Refraction: 1.612 ; (13)Molar Refractivity: 65.14 cm3 ; (14)Molar Volume: 187.3 cm3 ; (15)Polarizability: 25.82×10-24 cm3 ; (16)Surface Tension: 69.8 dyne/cm ; (17)Enthalpy of Vaporization: 79.28 kJ/mol ; (18)Vapour Pressure: 2.71E-10 mmHg at 25°C.

People can use the following data to convert to the molecule structure. SMILES: O[C@@H]1C[C@@H](C(O)=O)N(C1)C(=O)OCc2ccccc2; InChI: InChI=1/C13H15NO5/c15-10-6-11(12(16)17)14(7-10)13(18)19-8-9-4-2-1-3-5-9/h1-5,10-11,15H,6-8H2,(H,16,17)/t10-,11+/m1/s1. 

The N-Cbz-Hydroxy-L-proline has many suppliers, such as GL Biochem (Shanghai) Ltd., Nanjing Panfeng Chemical Co., Ltd., Shanghai Demo Chemical Co., Ltd., Shanghai Dere Finechem Co., Ltd., Sichuan Emei Ronggao Biochemicals Co., Ltd., Sichuan Tongsheng Amino Acids Co., Ltd. and Yangzhou Baosheng Bio-Chemical Co., Ltd..