Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 137234 > 

137234-62-9

Basic Information
CAS No.: 137234-62-9
Name: Voriconazole
Molecular Structure:
Molecular Structure of 137234-62-9 (Voriconazole)
Formula: C16H14F3N5O
Molecular Weight: 349.31047 [g/mol] .
Synonyms: 4-Pyrimidineethanol, alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-,(alphaR,betaS)-;DRG-0301;UK-109,496;UNII-JFU09I87TR;Vfend;VRC;
EINECS: 629-701-5
Density: 1.42 g/cm3
Melting Point: 127-130 °C
Boiling Point: 508.6 °C at 760 mmHg
Flash Point: 261.4 °C
Solubility:
Appearance: cyrstalline solid
Hazard Symbols: HarmfulXn
Risk Codes: 22-36/38
Safety: 26-36
Transport Information:
PSA: 76.72000
LogP: 2.17690
Synthetic route
188416-34-4, 137234-71-0

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane for 0.5h;92%
With sodium hydrogencarbonate In water; ethyl acetate90.47%
With sodium hydroxide In water at 45 - 55℃; for 2.5h; Product distribution / selectivity;87.22%

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol R-(-)-10-camphorsulfonate

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydroxide In dichloromethane; water pH=11 - 12;92%

voriconazole L-camphorsulfate

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane for 0.5h;92%
With sodium hydroxide In dichloromethane; water at 15 - 25℃; pH=10 - 11;

voriconazole L-camphor sulfonate

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane for 0.5h;90.8%
With sodium hydroxide In dichloromethane; water pH=12.3; Product distribution / selectivity; Alkaline aqueous solution; Industry scale;72%
With sodium hydroxide In dichloromethane; water pH=11; Product distribution / selectivity; Alkaline aqueous solution;

C26H28F3N5O5S

137234-62-9

voriconazole

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In ethanol under 760.051 Torr;86.3%
188416-38-8

(2R,3S)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1 yl)butan-2-ol

137234-62-9

voriconazole

Conditions
ConditionsYield
With palladium 10% on activated carbon; potassium formate In ethanol; water at 30℃; for 1h; Temperature; Reagent/catalyst; Inert atmosphere;84.9%
With palladium 10% on activated carbon; hydrogen; sodium acetate In water; toluene at -21 - 40℃; under 3750.38 Torr; for 22h;
848469-32-9

(2R,3S)-2-(2,4-diflurophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1yl)butan-2-ol R-(-)-10-camphor sulphonate salt

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium carbonate In dichloromethane; water at 20℃; for 0.333333h; pH=~ 10; Product distribution / selectivity;76%
With sodium hydroxide In dichloromethane; water pH=11 - 12; Product distribution / selectivity;

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol ((1R,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1yl)methanesulfonate

137234-62-9

voriconazole

Conditions
ConditionsYield
With water In ethanol at 32.5℃; Concentration; Solvent; Temperature;76%

2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butane-2-ol

137234-62-9

voriconazole

Conditions
ConditionsYield
With [(1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid In methanol; acetone for 2h; Reflux;43%
With (R)-10-camphorsulfonic acid In methanol; acetone at 0 - 5℃; Resolution of racemate;40.1%
Multi-step reaction with 2 steps
1: acetone; methanol / 15 h / -20 - 25 °C
2: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
Multi-step reaction with 2 steps
1: methanol; acetone / Reflux
2: sodium hydroxide / water; dichloromethane / pH 11
View Scheme
1602485-93-7

5-fluoro-4-vinylpyrimidine

86404-63-9

1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazolyl)ethanone

137234-62-9

voriconazole

Conditions
ConditionsYield
With CuF(PPh3)3 methanol solvate; (R)-(−)-1-[(R)-2-(2′-diphenylphosphinophenyl)ferrocenyl]ethylbis(di-3,5-trifluoromethylphenyl)phosphine at 0℃; for 21.5h; Reagent/catalyst; Inert atmosphere;40%
188416-35-5

3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol

137234-62-9

voriconazole

Conditions
ConditionsYield
Stage #1: 3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol With 5%-palladium/activated carbon; hydrogen; sodium acetate In methanol at 25℃; under 760.051 Torr;
Stage #2: With [(1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid In methanol; acetone for 2h; Reflux;
35%
Multi-step reaction with 3 steps
1.1: sodium acetate / ethyl acetate; water / 0.5 h / 25 - 30 °C
1.2: 25 - 30 °C / 3677.86 Torr
1.3: 0.5 h / 20 - 25 °C
2.1: acetone; methanol / 15 h / -20 - 25 °C
3.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
Multi-step reaction with 4 steps
1.1: hydrogen; sodium acetate / palladium 10% on activated carbon / ethyl acetate; water / 25 - 30 °C / 3677.86 Torr
1.2: 0.5 h / 20 - 25 °C
1.3: 12.5 h / 25 - 30 °C
2.1: sodium hydroxide / dichloromethane; water / 0.5 h / pH 9 - 12
3.1: acetone; methanol / 15 h / -20 - 25 °C
4.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
Multi-step reaction with 4 steps
1.1: hydrogen; sodium acetate; sodium carbonate / palladium 10% on activated carbon / ethyl acetate; water / 25 - 30 °C / 3677.86 Torr
1.2: 0.5 h / 20 - 25 °C
1.3: 10 - 25 °C
2.1: potassium carbonate / dichloromethane; water / 0.5 h / pH 8 - 10
3.1: acetone; methanol / 15 h / -20 - 25 °C
4.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
288-88-0

1,2,4-Triazole

1474024-68-4

4-((S)-1-((R)-2-(2,4-difluorophenyl)oxirane-2-yl)ethyl)-5-fluoropyrimidine

A

1028563-65-6

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(4H-1,2,4-triazol-4-yl)butan-2-ol

B

(2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

C

137234-62-9

voriconazole

Conditions
ConditionsYield
In ethanol at 80℃; for 18h; Inert atmosphere;A 27%
B n/a
C n/a
1003706-87-3

4-bromo-5-fluoro-pyrimidine

(3S)-2-(2,4-difluorophenyl)-3-methyl-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

137234-62-9

voriconazole

Conditions
ConditionsYield
In tetrahydrofuran at -70 - 30℃; for 25h; Temperature; Inert atmosphere;26.3%

(3S)-2-(2,4-difluorophenyl)-3-methyl-[(1H-1,2,4-triazol-1-yl)methyl]oxirane

347418-42-2

2,4-dichloro-5-fluoropyrimidine

137234-62-9

voriconazole

Conditions
ConditionsYield
In tetrahydrofuran at -70 - 30℃; for 25h; Temperature; Inert atmosphere;20.7%

(2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

A

(2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

B

137234-62-9

voriconazole

Conditions
ConditionsYield
With hydrogen; sodium acetate; palladium on activated charcoal In ethanol at 20℃;
759-67-1

2-fluoro-3-oxopentanoic acid ethyl ester

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1) MeONa, MeOH
2: POCl3 / Heating
3: LDA / tetrahydrofuran
4: H2, AcONa / Pd/C / ethanol / 20 °C
View Scheme
137234-87-8

6-Ethyl-5-fluoropyrimidin-4(3H)-one

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: POCl3 / Heating
2: LDA / tetrahydrofuran
3: H2, AcONa / Pd/C / ethanol / 20 °C
View Scheme
137234-74-3

4-chloro-5-fluoro-6-ethylpyrimidine

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: LDA / tetrahydrofuran
2: H2, AcONa / Pd/C / ethanol / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: diisopropylamine; n-butyllithium / n-heptane; hexane; tetrahydrofuran / 0.25 h / -80 - -70 °C / Inert atmosphere
1.2: 2 h / -80 - -55 °C
1.3: -70 - -10 °C
2.1: sodium acetate / ethyl acetate; water / 0.5 h / 25 - 30 °C
2.2: 25 - 30 °C / 3677.86 Torr
2.3: 0.5 h / 20 - 25 °C
3.1: acetone; methanol / 15 h / -20 - 25 °C
4.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
Multi-step reaction with 5 steps
1.1: diisopropylamine; n-butyllithium / n-heptane; hexane; tetrahydrofuran / 0.25 h / -80 - -70 °C / Inert atmosphere
1.2: 2 h / -80 - -55 °C
1.3: -70 - -10 °C
2.1: hydrogen; sodium acetate / palladium 10% on activated carbon / ethyl acetate; water / 25 - 30 °C / 3677.86 Torr
2.2: 0.5 h / 20 - 25 °C
2.3: 12.5 h / 25 - 30 °C
3.1: sodium hydroxide / dichloromethane; water / 0.5 h / pH 9 - 12
4.1: acetone; methanol / 15 h / -20 - 25 °C
5.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
321589-01-9

2-(2,4difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)-butan-2-ol-R(-)-10-camphor sulphonate

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydroxide In dichloromethane; water at 25 - 35℃; pH=11 - 12; Alkaline conditions;
188416-28-6

1-(4-chloro-5-fluoropyrimidin-6-yl)bromoethane

86404-63-9

1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazolyl)ethanone

A

(2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

B

137234-62-9

voriconazole

Conditions
ConditionsYield
Stage #1: 1-(4-chloro-5-fluoropyrimidin-6-yl)bromoethane; 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazolyl)ethanone With zinc(II) chloride; zinc In tetrahydrofuran at -5 - 5℃; for 1h;
Stage #2: With ammonium formate; zinc In methanol at 20℃; for 16h;
Stage #3: Product distribution / selectivity; Heating / reflux;

3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride

A

(2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

B

137234-62-9

voriconazole

Conditions
ConditionsYield
With ammonium formate; zinc In methanol Product distribution / selectivity;

C10H16O4S*C16H14F3N5O

A

(2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

B

137234-62-9

voriconazole

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; ethyl acetate at 20 - 25℃;
182230-43-9

2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

137234-62-9

voriconazole

Conditions
ConditionsYield
Stage #1: 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol With (R)-10-camphorsulfonic acid In methanol; acetone at 25 - 60℃; for 2h;
Stage #2: With sodium hydroxide In dichloromethane; water; isopropyl alcohol at 20 - 30℃; pH=12 - 13; Product distribution / selectivity;
With (1S)-10-camphorsulfonic acid In methanol; acetone at 20 - 30℃; for 3.5h; Reflux;
Multi-step reaction with 2 steps
1: sodium hydroxide / water / 3 h / 45 °C
2: camphor-10-sulfonic acid / methanol; acetone
View Scheme
1289559-75-6

C6H5FN2O

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / ethanol / 5 h
2.1: triethylamine / dmap / dichloromethane / 20 - 30 °C
3.1: zinc; zinc(II) chloride / tetrahydrofuran / 0 - 30 °C
4.1: (R)-10-camphorsulfonic acid / acetone; methanol / 2 h / 25 - 60 °C
4.2: 20 - 30 °C / pH 12 - 13
View Scheme
1289559-65-4

1-(2,6-dichloro-5-fluoropyrimidin-4-yl)ethanone

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogen; sodium acetate / palladium on activated carbon / ethanol / 25 °C
2.1: sodium tetrahydroborate / ethanol / 5 h
3.1: triethylamine / dmap / dichloromethane / 20 - 30 °C
4.1: zinc; zinc(II) chloride / tetrahydrofuran / 0 - 30 °C
5.1: (R)-10-camphorsulfonic acid / acetone; methanol / 2 h / 25 - 60 °C
5.2: 20 - 30 °C / pH 12 - 13
View Scheme
1289559-66-5

1-(5-fluoropyrimidin-4-yl)ethanol

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dmap / dichloromethane / 20 - 30 °C
2.1: zinc; zinc(II) chloride / tetrahydrofuran / 0 - 30 °C
3.1: (R)-10-camphorsulfonic acid / acetone; methanol / 2 h / 25 - 60 °C
3.2: 20 - 30 °C / pH 12 - 13
View Scheme
51336-94-8

2-chloro-1-(2,4-dichlorophenyl)ethanone

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium carbonate / tetrahydrofuran / 7 h / 20 °C
2: lead; zinc; iodine / tetrahydrofuran / -15 - 20 °C / Inert atmosphere
3: ammonium formate / palladium on carbon / toluene / 3 h / 80 °C
4: acetone; methanol / 1 h / Reflux
5: sodium hydrogencarbonate / dichloromethane / 0.5 h
View Scheme
Multi-step reaction with 5 steps
1: potassium carbonate / tetrahydrofuran / 7 h / 20 °C
2: lead; zinc; iodine / tetrahydrofuran / 2 h / -15 - -10 °C / Inert atmosphere
3: ammonium formate / 10% palladium on charcoal / toluene / 3 h / 80 °C
4: acetone; methanol / 1 h / Reflux
5: sodium hydrogencarbonate / dichloromethane / 0.5 h
View Scheme
137234-87-8

6-ethyl-5-fluoro-4-hydroxypyrimidine

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: triethylamine / dichloromethane / 5 h / 20 °C
2: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / dichloromethane / 12 h / 45 - 50 °C
3: lead; zinc; iodine / tetrahydrofuran / -15 - 20 °C / Inert atmosphere
4: ammonium formate / palladium on carbon / toluene / 3 h / 80 °C
5: acetone; methanol / 1 h / Reflux
6: sodium hydrogencarbonate / dichloromethane / 0.5 h
View Scheme
Multi-step reaction with 5 steps
1.1: triethylamine / dichloromethane / 5 - 10 °C
1.2: 8 h / 10 - 55 °C / Reflux
1.3: 0.5 h / 15 - 20 °C
2.1: diisopropylamine; n-butyllithium / n-heptane; hexane; tetrahydrofuran / 0.25 h / -80 - -70 °C / Inert atmosphere
2.2: 2 h / -80 - -55 °C
2.3: -70 - -10 °C
3.1: sodium acetate / ethyl acetate; water / 0.5 h / 25 - 30 °C
3.2: 25 - 30 °C / 3677.86 Torr
3.3: 0.5 h / 20 - 25 °C
4.1: acetone; methanol / 15 h / -20 - 25 °C
5.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
Multi-step reaction with 6 steps
1.1: triethylamine / dichloromethane / 5 - 10 °C
1.2: 8 h / 10 - 55 °C / Reflux
1.3: 0.5 h / 15 - 20 °C
2.1: diisopropylamine; n-butyllithium / n-heptane; hexane; tetrahydrofuran / 0.25 h / -80 - -70 °C / Inert atmosphere
2.2: 2 h / -80 - -55 °C
2.3: -70 - -10 °C
3.1: hydrogen; sodium acetate / palladium 10% on activated carbon / ethyl acetate; water / 25 - 30 °C / 3677.86 Torr
3.2: 0.5 h / 20 - 25 °C
3.3: 12.5 h / 25 - 30 °C
4.1: sodium hydroxide / dichloromethane; water / 0.5 h / pH 9 - 12
5.1: acetone; methanol / 15 h / -20 - 25 °C
6.1: sodium hydroxide / dichloromethane; water / 0.25 h / pH 11 - 14
View Scheme
1237496-99-9

6-ethyl-5-fluoropyrimidin-4-yl methanesulfonate

137234-62-9

voriconazole

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / dichloromethane / 12 h / 45 - 50 °C
2: lead; zinc; iodine / tetrahydrofuran / -15 - 20 °C / Inert atmosphere
3: ammonium formate / palladium on carbon / toluene / 3 h / 80 °C
4: acetone; methanol / 1 h / Reflux
5: sodium hydrogencarbonate / dichloromethane / 0.5 h
View Scheme
Multi-step reaction with 5 steps
1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / dichloromethane / 12 h / 45 - 50 °C
2: lead; zinc; iodine / tetrahydrofuran / 2 h / -15 - -10 °C / Inert atmosphere
3: ammonium formate / 10% palladium on charcoal / toluene / 3 h / 80 °C
4: acetone; methanol / 1 h / Reflux
5: sodium hydrogencarbonate / dichloromethane / 0.5 h
View Scheme
150994-82-4

4-((1,3-bis(octanoyloxy)propan-2-yl)oxy)-4-oxobutanoic acid

137234-62-9

voriconazole

4-((1,3-bis(octanoyloxy)propan-2-yl)oxy)-4-oxobutanoate 4-((2S,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)-5-fluoropyrimidin-1-ium

Conditions
ConditionsYield
In acetonitrile at 50℃; for 6h;100%

(2E)-4-((1,3-bis(dodecanoyloxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid

137234-62-9

voriconazole

(2E)-4-((1,3-bis(dodecanoyloxy)propan-2-yl)oxy)-4-oxobut-2-enoate 4-((2S,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)-5-fluoropyrimidin-1-ium

Conditions
ConditionsYield
In acetonitrile at 50℃; for 3h;100%
137234-62-9

voriconazole

voriconazole hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water at 20℃; for 1h;100%
56456-50-9

(2-chloro-6-fluorophenyl)methanol

137234-62-9

voriconazole

194798-93-1

Bis(2-chloro-6-fluorobenzyl) (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butyl phosphate

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; anhydrous phosphorus trichloride; dihydrogen peroxide In dichloromethane; tert-butyl methyl ether; water88%
137234-62-9

voriconazole

1620283-07-9

C16H13F3N6O3

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 20℃; for 3h;88%
With sulfuric acid; nitric acid at 0 - 20℃; for 3h;77%

C9H16ClNO5

137234-62-9

voriconazole

C20H22F3N6O4(1+)*I(1-)

Conditions
ConditionsYield
Stage #1: C9H16ClNO5; voriconazole With potassium iodide In acetonitrile for 15h; Reflux;
Stage #2: With hydrogenchloride; water In methanol at 50 - 55℃; for 20h;
Stage #3: In methanol; tert-butyl methyl ether at 10 - 65℃; for 18h;
87%
137234-62-9

voriconazole

C16H14F3N5O*HNO3

Conditions
ConditionsYield
With nitric acid In methanol; water86.62%
432037-32-6

chloromethyl 2-methoxyethyl carbonate

137234-62-9

voriconazole

C21H23F3N5O5(1+)*Cl(1-)

Conditions
ConditionsYield
In acetonitrile for 10h; Reflux;85%
432037-32-6

chloromethyl 2-methoxyethyl carbonate

137234-62-9

voriconazole

C21H23F3N5O5(1+)*Cl(1-)

Conditions
ConditionsYield
In acetonitrile for 12h; Reflux;80%
431894-46-1

chloromethyl 2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethyl carbonate

137234-62-9

voriconazole

C38H56F3N5O15(2+)*2Cl(1-)

Conditions
ConditionsYield
In acetonitrile for 14h; Reflux;79%
137234-62-9

voriconazole

voriconazole hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol; water78.62%
79-31-2

isobutyric Acid

137234-62-9

voriconazole

A

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-6-isopropylpyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

B

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-2,6-diisopropylpyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Conditions
ConditionsYield
With bis-[(trifluoroacetoxy)iodo]benzene; 9-mesityl-10-methylacridinium ion In acetonitrile at 20℃; Irradiation;A 77%
B 11%
76-05-1

trifluoroacetic acid

137234-62-9

voriconazole

(2R,3S)-2-(5-bromo-2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol trifluoroacetic acid

Conditions
ConditionsYield
With N-Bromosuccinimide for 16h; Inert atmosphere;73%

potassium trifluoro(isopropenyl)borate(1-)

137234-62-9

voriconazole

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-6-isopropylpyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate; trifluoroacetic acid; 9-(2-mesityl)-10-methylacridinium perchlorate In water; acetonitrile at 20℃; for 10h; Inert atmosphere; Schlenk technique; Irradiation; regioselective reaction;72%

C9H17ClN2O4

137234-62-9

voriconazole

C20H23F3N7O3(1+)*I(1-)

Conditions
ConditionsYield
Stage #1: C9H17ClN2O4; voriconazole With potassium iodide In acetonitrile for 15h; Reflux;
Stage #2: With hydrogenchloride; water In methanol at 50 - 55℃; for 20h;
Stage #3: In methanol; tert-butyl methyl ether at 10 - 65℃; for 15h;
70%
3144-16-9

(1S)-10-camphorsulfonic acid

137234-62-9

voriconazole

848469-32-9

(2R,3S)-2-(2,4-diflurophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1yl)butan-2-ol R-(-)-10-camphor sulphonate salt

Conditions
ConditionsYield
In methanol; acetone at 30 - 50℃; for 1.33333h; Heating / reflux;65%

C23H43ClN4O8

137234-62-9

voriconazole

C24H33F3N9O3(1+)*I(1-)

Conditions
ConditionsYield
Stage #1: C23H43ClN4O8; voriconazole With potassium iodide In acetonitrile for 15h; Reflux;
Stage #2: With hydrogenchloride; water In methanol at 50 - 55℃; for 20h;
Stage #3: In methanol; tert-butyl methyl ether at 10 - 65℃; for 18h;
65%
1402915-09-6

chloromethyl (2-methoxyethyl)carbamate

137234-62-9

voriconazole

C21H24F3N6O4(1+)*I(1-)

Conditions
ConditionsYield
Stage #1: chloromethyl (2-methoxyethyl)carbamate; voriconazole With potassium iodide In acetonitrile for 15h; Reflux;
Stage #2: In methanol; tert-butyl methyl ether at 10 - 65℃; for 20h;
63%
137234-62-9

voriconazole

98-89-5

Cyclohexanecarboxylic acid

(2R,3S)-3-(6-cyclohexyl-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Conditions
ConditionsYield
With hydrogenchloride; cerium(III) chloride heptahydrate; tetrabutyl-ammonium chloride In 2,2,2-trifluoroethanol; water for 17h; Schlenk technique; Inert atmosphere; Electrochemical reaction; Irradiation;60%

potassium trifluoro(isopropenyl)borate(1-)

76-05-1

trifluoroacetic acid

137234-62-9

voriconazole

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-6-isopropylpyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol trifluoroacetic acid

Conditions
ConditionsYield
Stage #1: potassium trifluoro(isopropenyl)borate(1-); voriconazole With manganese triacetate; acetic acid In water at 50℃; for 18h; Inert atmosphere;
Stage #2: trifluoroacetic acid In water; acetonitrile Inert atmosphere;
58%

silver perchlorate

137234-62-9

voriconazole

Ag(1+)*ClO4(1-)*2C16H14F3N5O

Conditions
ConditionsYield
In ethanol; water58%
  • Display:default sort

    New supplier

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Product technology and quality stability,perennial production,to meet the supply demand. Product technology and quality stability,perennial production,to meet the supply demand. Quality: 1. Order products, before delivery, according to customer nee

    Chongqing Lummy Longyu Pharmaceutical Co.,Ltd. is a wholly-owned subsidiary of Chongqing Lummy Pharmaceutical Co.,Ltd., which was established in 1999 and listed on the Growth Enter

  •  Chongqing Lummy Long Yu Pharmaceutical Co. ,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15823366292

    Address:Chongqing

       Inquiry Now

  • Voriconazole 99% Manufactuered in China best quality

  • Casno:

    137234-62-9

    Voriconazole 99% Manufactuered in China best quality

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Product Name: Voriconazole Synonyms: Voriconazole2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;Voriconazole solution;(2R,3S)-2-(2,4-Difluorophenyl)-3;2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1,

    Wuhan Zenuo Biopharmaceutical Technology Co., Ltd. is a global biopharmaceutical and chemical enterprise, mainly engaged in the customized synthesis, large-scale production and sal

  •  Wuhan Zenuo Biological Medicine Technology Co Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:(+86-27)8700-2750

    Address:Floor 19th,No.76,Longyang Road

       Inquiry Now

  • Voriconazole Manufacturer/High quality/Best price/In stock

  • Casno:

    137234-62-9

    Voriconazole Manufacturer/High quality/Best price/In stock

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0/Kilogram

    DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • Voriconazole CAS No.137234-62-9

  • Casno:

    137234-62-9

    Voriconazole CAS No.137234-62-9

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

    Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd (JL Pharm) is established in 2012 at the beautiful West Lake – Hangzhou city, China. The company's main business includes R&D, Produ

  •  Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-571-85829053

    Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area

       Inquiry Now

  • voriconazole

  • Casno:

    137234-62-9

    voriconazole

    Min.Order: 1000 Gram

    FOB Price:  USD $ 1100.0-1100.0/Gram

    chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

    Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of

  •  Hebei yanxi chemical co.,LTD.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-0311-66561638

    Address:Zhang zhe, guangzong county, xingtai city, hebei province

       Inquiry Now

  • High quality Voriconazole Cas 137234-62-9 with factory best price and good service

  • Casno:

    137234-62-9

    High quality Voriconazole Cas 137234-62-9 with factory best price and good service

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Unique advantages of Voriconazole Cas 137234-62-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to almost white crystalline powder Storage:Cool dry place Packa

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

  •  Wuhan Fortuna Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-59207852

    Address:A2705,Dong Yi Shi Qu,129# XinHua Road,WuHan,China

       Inquiry Now

  • 137234-62-9, buy 99% Voriconazole from China manufacturer and seller

  • Casno:

    137234-62-9

    MSDS/COA Download

    137234-62-9, buy 99% Voriconazole from China manufacturer and seller

    Min.Order: 100 Gram

    FOB Price:  USD $ 3.0-5.0/Gram

    We provide DOOR-TO-DOOR shipping, including customs clearance, more details please contact with us, or visit our website: www.whmulei.com Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating pro

    Mulei (Wuhan) New Material Technology Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermedia

  •  WUHAN MULEI NEW MATERIAL CO., LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619831967063

    Address:Office1201#, Block C, Hanjie Headquarters International Plaza, Zhongbei Rd, Wuchang District, Wuhan

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 0.0-0.0/Metric Ton

    1)Combination With the CYP3A4 substrates, terfenadine, sirolimus, astemizole, cisapride, pimozide or quinidine , can increase blood concentrations of this drug, leading to QT prolongation, and occasionally torsades de pointes ventricular tachycardi

    TNJ is a chemical company since 2001. Our specialization, your confidence-we keep committing to meet the needs of markets and customers with our innovative technology and high stab

  •  Hefei TNJ chemical industry co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-551-65418695

    Address:B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

  •  Henan Allgreen Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-0371-87507775

    Address:No 260 Dongming Road,Jinshui District

       Inquiry Now

  • High Quality 99% CAS 137234-62-9 Voriconazole Powder

  • Casno:

    137234-62-9

    MSDS/COA Download

    High Quality 99% CAS 137234-62-9 Voriconazole Powder

    Min.Order: 50 Kilogram

    FOB Price:  USD $ 25.0-30.0/Kilogram

    1. Who are we We are based in Shaanxi, China, start from 2018,sell to North America(00.00%), Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%), Eastern Europe(00.00%). There are total about 11-50 people in our office. 2. How can

    Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of S

  •  Xi'an Julong Bio-Tech Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+008618049624045

    Address:Xi'an

       Inquiry Now

  • Anti-fungal API raw material 99% Voriconazole powder

  • Casno:

    137234-62-9

    Anti-fungal API raw material 99% Voriconazole powder

    Min.Order: 500 Kilogram

    FOB Price:  USD $ 31.7-39.8/Kilogram

    Anti-fungal API raw material 99% Voriconazole powder Xi'an Quanao Biotech Co., Ltd. is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal e

    Xi 'an Quanao Biotech Co., Ltd. with 10 years experience in plant extract filed. Focus on the research, production and sale of Plant and Animal extract ,Medical intermediate ,compl

  •  Xi'an Quanao Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-29-86719484

    Address:B-1604,Juncheng Guoji, Taiyuan Road, Weiyang distirct

       Inquiry Now

  • Bulk Voriconazole Powder

  • Casno:

    137234-62-9

    MSDS/COA Download

    Bulk Voriconazole Powder

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-1.0/Kilogram

    1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery by well-reputed shipping lines. 4.Trial order is available for testing after samples. 5.We will inform you all the information at every stage in advance. 6.P

    Shaanxi greenyo biotech co., ltd is one specialized company which engaged in the naturalplant extracts, pharmaceutical intermediates, chemical raw materials research and developmen

  •  Shaanxi Greenyo Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-29-81772657

    Address:Gaoxin 4th road, High-tech zone,

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aro

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 1.0-2.0/Metric Ton

    Product Name Voriconazole Purity 99% CAS NO 137234-62-9 Appea

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

       Inquiry Now

  • TIANFUCHEM--137234-62-9--Voriconazole in stock

  • Casno:

    137234-62-9

    TIANFUCHEM--137234-62-9--Voriconazole in stock

    Min.Order: 1 Metric Ton

    FOB Price:  USD $ 2000.0-2000.0/Metric Ton

    TIANFUCHEM--137234-62-9--Voriconazole in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business relationship

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • High Quality Apis Voriconazole 99% Purity

  • Casno:

    137234-62-9

    High Quality Apis Voriconazole 99% Purity

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-2.0/Gram

    1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us. 2, Payment method: for e

    Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves

  •  Hubei Jusheng Technology Co., Ltd.,

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18871490254

    Address:High-tech Industrial Park,Tianmen city,Hubei province.

       Inquiry Now

  • Antifungal Series Voriconazoles Raw Powder 137234-62-9

  • Casno:

    137234-62-9

    Antifungal Series Voriconazoles Raw Powder 137234-62-9

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool & dr

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8618874586545

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • Manufacturer supply CAS 137234-62-9 with best quality

  • Casno:

    137234-62-9

    Manufacturer supply CAS 137234-62-9 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0/Kilogram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • BLOOM TECH Advanced API/Technology support Voriconazole CAS 137234-62-9

  • Casno:

    137234-62-9

    MSDS/COA Download

    BLOOM TECH Advanced API/Technology support Voriconazole CAS 137234-62-9

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Inquiry guide 1.Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you. 2.Then we will provide the professional quotation list for you, it will be including all the factors in who

    WHO WE ARE 1.We Focus on the technology of Organic Synthesis since 2008. 2.API/Pharmaceutical intermediate/Fine chemical/New material/Extraction etc. 3.Chemical reagent: Over 300,0

  •  Shaanxi BLOOM TECH Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-29-86470566

    Address:Block A of Central Mansion, No.113 of Weiyang Rd, ETDZ, Xi'an, Shaanxi 710016, China

       Inquiry Now

  • Voriconazole/ LIDE PHARMA- Factory supply / Best price

  • Casno:

    137234-62-9

    Voriconazole/ LIDE PHARMA- Factory supply / Best price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

    LIDE PHARMACEUTICALS LIMITED is one of the fastest growing pharmaceutical company in China. We have developed strategic partnership with our manufacturing associates having state o

  •  LIDE PHARMACEUTICALS LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

       Inquiry Now

  • Voriconazole CAS NO.137234-62-9

  • Casno:

    137234-62-9

    MSDS/COA Download

    Voriconazole CAS NO.137234-62-9

    Min.Order: 10 Gram

    FOB Price:  USD $ 2.0-2.0/Gram

    superiority advantages: my company is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philoso

    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

       Inquiry Now

  • Voriconazole  99%

  • Casno:

    137234-62-9

    Voriconazole 99%

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 100.0-100.0/Kilogram

    1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermed

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 80.0-150.0/Kilogram

    Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

    Baoji Guokang Healthchem co.,ltd located in Baoji High-tech Zone,is epitomizing international,cooperative and honest.We are a young company full of action and energy,and our profes

  •  Baoji Guokang Healthchem co.,ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-917-3909592

    Address:China

       Inquiry Now

  • High Purity Antifungal Agent Voriconazole CAS 137234-62-9 Voriconazole Powder

  • Casno:

    137234-62-9

    High Purity Antifungal Agent Voriconazole CAS 137234-62-9 Voriconazole Powder

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 20.0-40.0/Kilogram

    Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

    Hubei Hanways Pharmchem Co.,Limited is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. Now we

  •  HANWAYS CHEMPHARM CO.,LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18502787239(whatsapp)

    Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

       Inquiry Now

  • Hot Sales Voriconazole CAS NO.137234-62-9

  • Casno:

    137234-62-9

    Hot Sales Voriconazole CAS NO.137234-62-9

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-2.0/Gram

    Price, Service, Company and Transport Advantage: 1.Place of Origin China with Super quality by reasonable price. 2.Fast delivery by safe express way to all the country. 3.Has a number of highly qualified engineers a

    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

  •  Jilin Tely Imp.& Exp.Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

       Inquiry Now

  • Voriconazole CAS NO.137234-62-9

  • Casno:

    137234-62-9

    Voriconazole CAS NO.137234-62-9

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

    Changchun Artel Import and Export Trade Co., Ltd. is located in Changchun City, Jilin Province. It is a high-tech modern private enterprise specializing in the research, developme

  •  Changchun Artel lmport and Export trade company

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0431-80543058

    Address:Dianshi Plazza,Chaoyang District

       Inquiry Now

  • Voriconazole Powder CAS 137234-62-9 99% High Purity

  • Casno:

    137234-62-9

    Voriconazole Powder CAS 137234-62-9 99% High Purity

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

    WUHAN WONDA PHARMACEUTICAL AND CHEMICAL LIMITED is specializing in custom synthesis, manufacture and import & export of nootropics, herbal extract, OLED etc. Wuhan Wonda Pharm & Ch

  •  Wuhan Wonda Pharm Limited

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:027-84306245

    Address:Wuhan Private Science and Technology Park , Wuhan, China

       Inquiry Now

  • CAS 137234-62-9 Voriconazole

  • Casno:

    137234-62-9

    MSDS/COA Download

    CAS 137234-62-9 Voriconazole

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1300.0-1300.0/Kilogram

    We do following terms : 1) Best quality 2) Many years experience in this field 3) Loyal customers in countries 4) Professional big supplier 5) Safe shipping 6) Various payment terms Product Name:

    CUSTOMIZED LAB Chemtn Biological Technology Limited is one of the leading RC chemicals producer in china,we have advanced equipment and high technology,

  •  Chemtn Biological Technology Limited

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+8615630194059

    Address:LB BLDG,Qiaoxi district,Shijiazhuang,china

       Inquiry Now

  • High Purity Voriconazole, CAS 137234-62-9

  • Casno:

    137234-62-9

    MSDS/COA Download

    High Purity Voriconazole, CAS 137234-62-9

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-3.0/Gram

    Our Service: 1. Best quality in your requirement 2. Competitive price in china market 3. Mature technical support 4. Professional logistic support 5 . Full experience of large numberscontainers loading in chinese sea port 6 .Fast

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8613397160123

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

       Inquiry Now

  • Hot sales 137234-62-9 Voriconazole with best price

  • Casno:

    137234-62-9

    MSDS/COA Download

    Hot sales 137234-62-9 Voriconazole with best price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1000.0-1500.0/Kilogram

    Hot sales 137234-62-9 Voriconazole with best price Our main products: Crovell is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride e

    Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group,which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector amon

  •  Hebei Guanlang Biotechnology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619930503256

    Address:No.66, Yuhua West Road

       Inquiry Now

  • Voriconazole 137234-62-9 Large in supply

  • Casno:

    137234-62-9

    Voriconazole 137234-62-9 Large in supply

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Synonyms: Voriconazole 2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;Voriconazole solution;(2R,3S)-2-(2,4-Difluorophenyl)-3;2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1,2,4-triazol-1-yl)butan-2-ol;2

    SHANGHAI MINSTAR CHEMICAL CO., LTD. is a leading, experienced, professional supplier of API & intermediates, plant extract, food additive, fine chemicals and industry chemicals, et

  •  Shanghai Minstar Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-21-18019205509

    Address:BUILDING 8, NO.1098, CHUANSHA ROAD, SHANGHAI, CHINA

       Inquiry Now

  • Supply  high quality Voriconazole(137234-62-9)

  • Casno:

    137234-62-9

    Supply high quality Voriconazole(137234-62-9)

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates fine chemicals custom synthesis, scale-up production and rare chemicals trade. We have experienced research staff, stron

    Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded t

  •  Career Henan Chemical Co

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-86658258

    Address:Building 3 of Innovation Park, East District of the National University Science Park

       Inquiry Now

  • Voriconazole

  • Casno:

    137234-62-9

    Voriconazole

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

    Shanghai BetterBioChem Co., Ltd. specializes in research, production of APIs, building blocks and key pharmaceutical intermediates. We provide our products from milligrams to kilog

  •  Shanghai BetterBioChem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18013506594

    Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

       Inquiry Now

  • ISO 9001   National Research Platform CAS No.  137234-62-9

  • Casno:

    137234-62-9

    ISO 9001 National Research Platform CAS No. 137234-62-9

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    1. Subsidiary of Institute of Chemistry, Henan Academy of Sciences, national research platform;2. About 30 years’ experience in this field since 1983;3. An experienced R&D team consisting of Doctors and Masters;4. Various types of analytical instrume

    Zhengzhou Kingorgchem Chemical Technology Co., Ltd. was founded on the basis of Organophosphorus Chemistry Lab of Institute of Chemistry Henan Academy of Sciences in 2015. The

  •  Zhengzhou Kingorgchem Chemical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-65511936

    Address:NO.56,Hongzhuan Road

       Inquiry Now

  • Voriconazolewith factory price

  • Casno:

    137234-62-9

    Voriconazolewith factory price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Wuhan Sun-shine Bio-technology Corporation Limited is specializing in the anticancer, antitumor,heart head blood-vessel,pharmaceutical intermediates,fine Chemicals production and customization. Company has strong ability of research and development

    Wuhan Sun-shine Bio-technology Corporation Limited (Shanghai Sun-shine Chemical Technology Corporation Limited) is a high-tech enterprise engaged inR&D and sales of related compoun

  •  Wuhan Sun-shine Bio-technology Corporation Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-27-65522452

    Address:No. 388 Gaoxin Road(No. 2), East Lake Hi-tech Development Zone, Wuhan, Hubei Province, PRC

       Inquiry Now

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Molecular structure of Voriconazole (CAS NO.137234-62-9) is:

Product Name: Voriconazole
CAS Registry Number: 137234-62-9
IUPAC Name:  (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
Molecular Weight: 349.31047 [g/mol]
Molecular Formula: C16H14F3N5O
XLogP3-AA: 1.5
H-Bond Donor: 1
H-Bond Acceptor: 8
Melting Point: 127-130 °C
Surface Tension: 45.1 dyne/cm
Density: 1.42 g/cm3
Flash Point: 261.4 °C
Enthalpy of Vaporization: 82.02 kJ/mol
Boiling Point: 508.6 °C at 760 mmHg
Vapour Pressure: 3.63E-11 mmHg at 25°C 
Product Categories: API; Antifungal (Systemic); Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals

History

   London, UK, 16 December 2008 - The effectiveness of voriconazole in combating fungal infections has been confirmed by a new study to be featured in the International Journal of Antimicrobial Agents ,published by Elsevier.

Uses

 Voriconazole (CAS NO.137234-62-9) is generally used to treat serious, invasive fungal infections. These are generally seen in patients who are immunocompromised, and include invasive candidiasis, invasive aspergillosis, and certain emerging fungal infections.

Toxicity Data With Reference

    The most common side effects associated with voriconazole(137234-62-9) include transient visual disturbances, fever, rash, vomiting, nausea, diarrhea, headache, sepsis, peripheral edema, abdominal pain, and respiratory disorder.This medication may also cause the skin to peel easily. It is best to apply lotion and/or coconut oil to help with this side effect.

Safety Profile

Safty information about Voriconazole (CAS NO.137234-62-9) is:
Hazard Codes: HarmfulXn
Risk Statements: 22-36/38 
R22:Harmful if swallowed. 
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

Specification

 Voriconazole , its cas register number is 137234-62-9. It also can be called Voriconazole [USAN:INN:BAN] ; (alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ; 4-Pyrimidineethanol, alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-,(alphaR,betaS)- ; DRG-0301 ; UK-109,496 ; UNII-JFU09I87TR ; VRC ; Vfend ; Voriconazole ; (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ; 4-Pyrimidineethanol, alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-, (R-(R*,S*))- . It is a cyrstalline solid.