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Basic Information
| CAS No.: | 141-22-0 |
|---|---|
| Name: | RICINOLEIC ACID |
| Article Data: | 26 |
| Molecular Structure: | |
|
|
|
| Formula: | C18H34O3 |
| Molecular Weight: | 298.466 |
| Synonyms: | 9-Octadecenoicacid, 12-hydroxy-, [R-(Z)]-;Ricinoleic acid (8CI);(R)-12-Hydroxyoleic acid;12-D-Hydroxy-9-cis-octadecenoic acid;12-Hydroxy-cis-9-octadecenoic acid;12-Hydroxyoctadeca-9-enoic acid;CS 80;Cenwax C;Edenor Ri 90;NSC 281242;Nouracid CS 80;Ricinolic acid; |
| EINECS: | 205-470-2 |
| Density: | 0.957 g/cm3 |
| Melting Point: | 〈10oC |
| Boiling Point: | 416.4 °C at 760 mmHg |
| Flash Point: | 219.8 °C |
| Appearance: | yellow viscous liquid |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36 |
| PSA: | 57.53000 |
| LogP: | 5.07930 |
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Synthetic route
Conditions
| Conditions | Yield |
|---|---|
| With lithium hydroxide; water In tetrahydrofuran for 6h; Ambient temperature; | 83% |
- 41015-43-4
methyl acetyl ricinoleate
A
- 141-22-0
Ricinoleic acid
B
- 41989-07-5
methyl ricinoleate
C
- 111766-70-2
(Z)-12-Acetoxy-octadec-9-enoic acid
Conditions
| Conditions | Yield |
|---|---|
| With sodium hydroxide In methanol under 750.06 Torr; | A 15% B 65% C 20% |
...Expand
Conditions
| Conditions | Yield |
|---|---|
| With ethylaluminum dichloride In dichloromethane at 0℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; | |
| With ethylaluminum dichloride In dichloromethane at 0℃; for 1h; Yield given. Yields of byproduct given; |
...Expand
- 141-22-0
Ricinoleic acid
Conditions
| Conditions | Yield |
|---|---|
| With alkaline solution |
Conditions
| Conditions | Yield |
|---|---|
| ricinoleate of/the/ ricinolic acid; |
...Expand
D
- 141-22-0
Ricinoleic acid
Conditions
| Conditions | Yield |
|---|---|
| With lipase AK In tetrahydrofuran; phosphate buffer at 20℃; for 1h; Product distribution; Further Variations:; Reagents; Solvents; Temperatures; | A 11 % Spectr. B n/a C n/a D 24 % Spectr. |
...Expand
Conditions
| Conditions | Yield |
|---|---|
| With alkali In methanol; water |
- 141-22-0
Ricinoleic acid
Conditions
| Conditions | Yield |
|---|---|
| With sodium hydroxide In methanol; water |
- 141-22-0
Ricinoleic acid
Conditions
| Conditions | Yield |
|---|---|
| With potassium hydroxide In ethanol for 1h; Reflux; |
Conditions
| Conditions | Yield |
|---|---|
| With dmap; dicyclohexyl-carbodiimide In toluene at 20℃; for 18h; | 100% |
| With dmap; dicyclohexyl-carbodiimide In toluene at 20℃; for 18h; | 100% |
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RICINOLEIC ACID
Chemistry
Molecular Formula:C18H34O3
Molecular Weight:298.52
Density:0.940 g/mL at 20 °C(lit.)
Melting Point:〈10 °C
Boiling Point:416.4 °C at 760 mmHg
Flash Point:219.8 °C
Storage temp.:2-8°C
Merck:8211
Solubility:Very slightly soluble in water
Appearance:Clear amber liquid with some foots
Properties:Liquid
Ricinoleic Acid's Synonyms: 12-HYDROXY-9-OCTADECENOIC ACID;(+)-12-HYDROXYOLEIC ACID;12-HYDROXYOLEIC ACID;DELTA 9 CIS 12 HYDROXY OCTADECENOIC ACID;RICINOLEIC ACID;RICINOLIC ACID;[R]-12-HYDROXY-CIS-9-OCTADECANOIC ACID;[R]-12-HYDROXY-CIS-9-OCTADECENOIC ACID
Molecular Weight:298.52
Density:0.940 g/mL at 20 °C(lit.)
Melting Point:〈10 °C
Boiling Point:416.4 °C at 760 mmHg
Flash Point:219.8 °C
Storage temp.:2-8°C
Merck:8211
Solubility:Very slightly soluble in water
Appearance:Clear amber liquid with some foots
Properties:Liquid
Ricinoleic Acid's Synonyms: 12-HYDROXY-9-OCTADECENOIC ACID;(+)-12-HYDROXYOLEIC ACID;12-HYDROXYOLEIC ACID;DELTA 9 CIS 12 HYDROXY OCTADECENOIC ACID;RICINOLEIC ACID;RICINOLIC ACID;[R]-12-HYDROXY-CIS-9-OCTADECANOIC ACID;[R]-12-HYDROXY-CIS-9-OCTADECENOIC ACID
Uses
Ricinoleic acid can used as analgesic and anti-inflammatory
Toxicity Data With Reference
| 1. | scu-rbt TDLo:390 mg/kg/17W-I:ETA | CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 137 (1943),760. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Ricinoleic Acid's Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS VJ3150000