Products Categories
| CAS No.: | 145783-15-9 |
|---|---|
| Name: | 4,6-dichloro-2-propylthiopyrimidine-5-amine |
| Article Data: | 28 |
| Molecular Structure: | |
|
|
|
| Formula: | C7H9Cl2N3S |
| Molecular Weight: | 238.141 |
| Synonyms: | 4,6-dichloro-2-propylthiopyrimidine-5-amine;5-amino-4,6-dichloro-2-propylthiopyrimidine;EX-7178;5-Amino-4,6-dichloro-2-(propylthio)pyrimidine; |
| EINECS: | 808-051-8 |
| Density: | 1.445 g/cm3 |
| Boiling Point: | 334.05 °C at 760 mmHg |
| Flash Point: | 155.828 °C |
| Solubility: | 100mg/L at 22℃ |
| Safety: | 24/25 |
| PSA: | 77.10000 |
| LogP: | 3.44890 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 211914-50-0N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride
- 145783-14-8
4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With ammonium molibdate; hydrogen; hypophosphorous acid; platinum on carbon In tert-butyl methyl ether at 20 - 65℃; under 7500.75 Torr; for 7h; Product distribution / selectivity; Inert atmosphere; | 100% |
| Stage #1: 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine With iron; acetic acid In methanol at 50℃; Stage #2: With sodium hydrogencarbonate In water; ethyl acetate Product distribution / selectivity; | 95% |
| With iron; acetic acid for 4h; | 73% |
- 1549834-66-3
4,6-dihydroxy-5-amino-2-(propylmercapto)pyrimidine hydrochloride
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With trichlorophosphate for 22.5h; Time; Concentration; Reflux; Sealed tube; | 96% |
| With trichlorophosphate for 22.5h; Time; Sealed tube; Reflux; | 96% |
| With pyridine; trichlorophosphate at 88 - 92℃; for 24h; | 84% |
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; trichlorophosphate at 75℃; for 4h; Reagent/catalyst; Temperature; | 93% |
| With trichlorophosphate for 24h; Reflux; Large scale; | 90% |
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With chlorine In chloroform at 30℃; for 6h; | 88% |
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| Stage #1: 4,6-dichloro-5-[(E)-2-(4-phenyl)diazenyl]-2-(propylsulfanyl)pyrimidine With ammonium formate; zinc In methanol; isopropyl alcohol for 0.166667h; Stage #2: With hydrogen; Raney Ni In methanol; isopropyl alcohol at 20℃; under 7500.75 Torr; for 11h; Product distribution / selectivity; | 78% |
- 376608-73-0
4,6-dichloro-5-((E)-2-(4-methylphenyl)diazenyl)-2-(propylsulfanyl)pyrimidine
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With hydrogen; 10 wt% platinum on carbon In ethyl acetate at 20 - 40℃; under 2250.23 Torr; for 0.5 - 2.5h; Product distribution / selectivity; | |
| Multi-step reaction with 2 steps 1: ammonium formate; zinc / methanol; isopropyl alcohol / 0.33 h 2: hydrogen / 11 h / 20 °C View Scheme |
A
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With hydrogen; platinum on carbon In methanol; isopropyl alcohol at 20℃; under 4500.45 Torr; for 32h; |
- 145783-12-6
4,6-dihydroxy-2-(propylsulfanyl)pyrimidine
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1.1: sodium acetate; sodium hydroxide / ethanol; water / 20 °C 1.2: 0.5 h / 0 °C 1.3: 0 - 5 °C 2.1: pyridine; trichlorophosphate / toluene / 4.75 h / 70 °C 3.1: ammonium formate; zinc / methanol; isopropyl alcohol / 0.33 h 4.1: hydrogen / 11 h / 20 °C View Scheme | |
| Multi-step reaction with 3 steps 1: nitric acid; acetic acid / 55 °C 2: trichlorophosphate / N,N-dimethyl acetamide / Reflux 3: ammonia View Scheme | |
| Multi-step reaction with 3 steps 1: nitric acid; acetic acid / 2 h / Cooling with ice 2: dmap; trichlorophosphate / 5 h / Reflux 3: iron; acetic acid / methanol / 2 h / Reflux View Scheme |
- 376608-72-9
4,6-dihydroxy-5-((E)-2-(4-methylphenyl)diazenyl)-2-(propylsulfanyl)pyrimidine
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: pyridine; trichlorophosphate / toluene / 4.75 h / 70 °C 2: ammonium formate; zinc / methanol; isopropyl alcohol / 0.33 h 3: hydrogen / 11 h / 20 °C View Scheme |
- 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine
| Conditions | Yield |
|---|---|
| With hydrogen at 20℃; for 11h; |
- 14586-54-01,10-PHENANTHROLINE IRON(II) PERCHLORATE
- 14588-08-0Bis(triphenylphosphinepalladium) acetate
- 145915-30-64-Bromo-2-methoxybenzenethiol
- 145926-28-9(R)-(+)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHALENECHLORO(P-CYMENE)RUTHENIUM CHLORIDE
- 1460-18-0Pentadecanedioic acid
- 146126-21-8GLYCERYL POLYMETHACRYLATE
- 1462-03-91-Methylcyclopentanol
- 1462-05-11-(propan-2-yl)cyclopentanol
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Specification
The CAS registry number of 5-Pyrimidinamine, 4,6-dichloro-2-(propylthio)- is 145783-15-9. This chemical is also known as 4,6-Dichloro-2-propylthiopyrimidine-5-amine. The molecular formula of it is C7H9Cl2N3S and molecular weight is 238.13746. Its systematic name and IUPAC name are the same which is called 4,6-dichloro-2-(propylsulfanyl)pyrimidin-5-amine.
Physical properties about this chemical are: (1)ACD/LogP: 3.66; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 4; (4)ACD/LogD (pH 7.4): 4; (5)ACD/BCF (pH 5.5): 942; (6)ACD/BCF (pH 7.4): 942; (7)ACD/KOC (pH 5.5): 4680; (8)ACD/KOC (pH 7.4): 4680; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 4; (12)Index of Refraction: 1.615; (13)Molar Refractivity: 57.523 cm3; (14)Molar Volume: 164.803 cm3; (15)Surface Tension: 65.883 dyne/cm; (16)Density: 1.445 g/cm3; (17)Flash Point: 155.828 °C; (18)Enthalpy of Vaporization: 57.697 kJ/mol; (19)Boiling Point: 334.05 °C at 760 mmHg; (20)Vapour Pressure: 0 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: Clc1nc(SCCC)nc(Cl)c1N
(2)InChI: InChI=1/C7H9Cl2N3S/c1-2-3-13-7-11-5(8)4(10)6(9)12-7/h2-3,10H2,1H3
(3)InChIKey: CJJLJBFJNXMANZ-UHFFFAOYAU
-
Premium Related Products
