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1461-25-2

Basic Information
CAS No.: 1461-25-2
Name: Tetra-n-butyltin
Article Data: 202
Molecular Structure:
Molecular Structure of 1461-25-2 (Tetra-n-butyltin)
Formula: C16H36Sn
Molecular Weight: 347.172
Synonyms: NSC 22330;NSC 28131;NSC 65524;Tetra-n-butylstannane;Tetrabutylstannane;Tetrabutyltin;Tetrabutyltin(IV);
EINECS: 215-960-8
Density: 1.057 g/mL at 25 °C(lit.)
Melting Point: -97 °C(lit.)
Boiling Point: 275.347 °C at 760 mmHg
Flash Point: 158.926 °C
Solubility: insoluble in water
Appearance: colourless liquid
Hazard Symbols: ToxicT, DangerousN
Risk Codes: 21-25-36/38-48/23/25-50/53-48/23
Safety: 35-36/37/39-45-60-61
Transport Information: UN 1760 8/PG 2
PSA: 0.00000
LogP: 6.63560
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  • 1461-25-2              C16H36Sn                 Tetra-n-butyltin

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Chemistry

IUPAC Name: Tetrabutylstannane (1461-25-2)
Synonyms: (C4H9)4Sn;tetrabutyl-stannan ; Tetrabutyl-ti ; Tetra-n-butylcin ; Tetra-n-butylcin(czech) ; Tetra-normal-butyltin ; Tetra-n-butylstannane ; Tetra-n-butyltin
CAS: 1461-25-2
Molecular Formula: C16H36Sn
Molecular Weight: 347.17
Molecular Structure:
EINECS: 215-960-8
Product Categories: Alkyl Metals;Classes of Metal Compounds;Grignard Reagents & Alkyl Metals;Sn (Tin) Compounds;Synthetic Organic Chemistry;Typical Metal Compounds
Mol File: 1461-25-2.mol
Flash Point: 158.9 °C 
Enthalpy of Vaporization: 49.31 kJ/mol 
Boiling Point: 275.3 °C at 760 mmHg
Vapour Pressure: 0.0086 mmHg at 25°C
Melting point:  -97 °C(lit.)
Refractive index:  n20/D 1.473(lit.)
Water Solubility:  insoluble
Stability: Stable, Incompatible with strong oxidizing agents. Combustible.
Appearance: Tetrabutylstannane (1461-25-2) is colourless liquid.

Uses

Tetrabutylstannane (1461-25-2) is used for the prodution of organic heat stabilizers and an important intermediate of catalyst of organic tin  (such as 2-butyl tin oxide, Dibutyltin dilaurate, etc.), which is also good for explosion-proof agent of  gasoline .

Toxicity Data With Reference

Organism

Test Type

Route

Reported Dose (Normalized Dose)

Effect

Source

mouse

LC50

inhalation

142mg/m3 (142mg/m3)

 

"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.

mouse

LD50

intravenous

56mg/kg (56mg/kg)

 

U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02221,

mouse

LD50

oral

6gm/kg (6000mg/kg)

 

Journal of Pharmaceutical Sciences. Vol. 56, Pg. 240, 1967.

mouse

LDLo

intramuscular

1389mg/kg (1389mg/kg)

peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
behavioral: muscle weakness

Annales Pharmaceutiques Francaises. Vol. 14, Pg. 88, 1956.

mouse

LDLo

intraperitoneal

174mg/kg (174mg/kg)

peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)
behavioral: muscle weakness

Annales Pharmaceutiques Francaises. Vol. 14, Pg. 88, 1956.

mouse

LDLo

parenteral

347mg/kg (347mg/kg)

peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage)

Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 239, Pg. 1091, 1954.

rabbit

LDLo

oral

> 5gm/kg (5000mg/kg)

 

Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.

rabbit

LDLo

skin

2gm/kg (2000mg/kg)

 

Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.

rat

LD50

intravenous

48mg/kg (48mg/kg)

behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"

"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.

rat

LD50

oral

1268mg/kg (1268mg/kg)

behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"

"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.

rat

LD50

subcutaneous

3082mg/kg (3082mg/kg)

behavioral: somnolence (general depressed activity)
gastrointestinal: "hypermotility, diarrhea"

"Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 201, 1999.

Safety Profile

 

Hazard Codes:  T,N
Risk Statements : 21-36/38-48/23/25-50/53
21:  Harmful in contact with skin
36/38: Tetrabutylstannane (1461-25-2) is  irritating to eyes and skin.
48/23/25:  Toxic: danger of serious damage to health by prolonged exposure through inhalation and if swallowed
50/53:  Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment 
Safety Statements:  35-36/37/39-45-60-61
35:  This material and its container must be disposed of in a safe way
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection
RIDADR:  UN 1760 8/PG 2
WGK Germany:  3
RTECS : WH8605000
TSCA : Yes