CAS No.1477-19-6,Benzarone Suppliers

Products Categories

Pharmaceutical (43)
Others (11)
Organic Chemicals (6)
Reagent (1)
Dyestuff and Pigment (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	1477-19-6
Name:	Benzarone
Article Data:	10

Formula:	C17H14 O3
Molecular Weight:	266.296
Synonyms:	Ketone,2-ethyl-3-benzofuranyl p-hydroxyphenyl (6CI,7CI,8CI);2-Ethyl-3-(4-hydroxybenzoyl)benzofuran; 2-Ethyl-3-(p-hydroxybenzoyl)benzofuran;2-Ethyl-3-benzofuranyl p-hydroxyphenyl ketone;2-Ethyl-4'-hydroxy-3-benzoylbenzofuran; Benzaron; Benzarone; Fagivil; Fragivil;Fragivix; L 2179-Labaz; L 2197; NSC 82134
EINECS:	216-026-2
Density:	1.234g/cm³
Melting Point:	124.3°
Boiling Point:	473.6°Cat760mmHg
Flash Point:	240.2°C
Safety:	Poison by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A flammable liquid. When heated to decomposition it emits acrid and irritating smoke and fumes. See also KETONES.
PSA:	50.44000
LogP:	3.93180

Synthetic route

: 3343-80-4
(2-ethylbenzofuran-3-yl)(4-methoxyphenyl)methanone

: 1477-19-6
benzarone

Conditions

Conditions	Yield
With aluminum (III) chloride In chloroform at 80℃; for 0.5h; Temperature; Reagent/catalyst; Large scale;	95%
Stage #1: (2-ethylbenzofuran-3-yl)(4-methoxyphenyl)methanone With sodium thioethylate In N,N-dimethyl-formamide at 125 - 130℃; for 1h; Stage #2: With water; ammonium chloride In N,N-dimethyl-formamide	90%
With sodium thioethylate In N,N-dimethyl-formamide at 125 - 130℃; for 1h;	90%

: 3562-84-3
benzbromarone

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Stage #1: benzbromarone With dichloro[1,1′-bis[bis(1,1-dimethylethyl)phosphino]ferrocene-P,P′]palladium; triethylamine In water at 20℃; for 0.0333333h; Stage #2: With 1,1,3,3-Tetramethyldisiloxane for 11.9667h;	86%

: 3131-63-3
2-ethylbenzofuran

: 100-07-2
4-methoxy-benzoyl chloride

: 1477-19-6
benzarone

Conditions

Conditions	Yield
With lewis acid In chloroform at 10 - 30℃; for 4h; Solvent; Temperature;	68.2%

: 3131-63-3
2-ethylbenzofuran

: 1486-50-6
4-(benzyloxy)benzoic acid chloride

A: 101596-43-4
3-benzyl-2-ethylbenzofuran

B: 1477-19-6
benzarone

Conditions

Conditions	Yield
With tin(IV) chloride; benzene

...Expand

: 90908-77-3
(4-acetoxy-phenyl)-(2-ethyl-benzofuran-3-yl)-ketone

: 1477-19-6
benzarone

Conditions

Conditions	Yield
With sodium hydroxide

: 3131-63-3
2-ethylbenzofuran

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tin (IV)-chloride; benzene 2: aq.-ethanolic NaOH-solution View Scheme
Multi-step reaction with 2 steps 1: tin (IV)-chloride; carbon disulfide 2: pyridine hydrochloride View Scheme
Multi-step reaction with 2 steps 1: tin(IV) chloride / carbon disulfide / 5 - 20 °C / Inert atmosphere; Cooling with ice 2: sodium thioethylate / N,N-dimethyl-formamide / 1 h / 125 - 130 °C View Scheme

: 27914-73-4
4-acetoxybenzoyl chloride

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tin (IV)-chloride; benzene 2: aq.-ethanolic NaOH-solution View Scheme

: 100-07-2
4-methoxy-benzoyl chloride

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tin (IV)-chloride; carbon disulfide 2: pyridine hydrochloride View Scheme
Multi-step reaction with 2 steps 1: tin(IV) chloride / carbon disulfide / 5 - 20 °C / Inert atmosphere; Cooling with ice 2: sodium thioethylate / N,N-dimethyl-formamide / 1 h / 125 - 130 °C View Scheme
Multi-step reaction with 2 steps 1: polystyrene-supported aluminum trichloride / dichloromethane / 1 h / 5 - 20 °C / Large scale 2: aluminum (III) chloride / chloroform / 0.5 h / 80 °C / Large scale View Scheme

: 1646-26-0
1-(benzo[b]furan-2-yl)ethanone

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: hydrazine / water; diethylene glycol / 120 - 190 °C 1.2: 6 h / 120 - 130 °C 2.1: tin(IV) chloride / carbon disulfide / 5 - 20 °C / Inert atmosphere; Cooling with ice 3.1: sodium thioethylate / N,N-dimethyl-formamide / 1 h / 125 - 130 °C View Scheme
Multi-step reaction with 3 steps 1.1: hydrazine / water; diethylene glycol / 120 - 190 °C 1.2: 6 h / 120 - 130 °C 2.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice 2.2: 6 h / 20 °C / Cooling with ice 3.1: sodium thioethylate / N,N-dimethyl-formamide / 1 h / 125 - 130 °C View Scheme

: 90-02-8
salicylaldehyde

: 1477-19-6
benzarone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: potassium carbonate / acetone / 6 h / Reflux 2.1: hydrazine / water; diethylene glycol / 120 - 190 °C 2.2: 6 h / 120 - 130 °C 3.1: tin(IV) chloride / carbon disulfide / 5 - 20 °C / Inert atmosphere; Cooling with ice 4.1: sodium thioethylate / N,N-dimethyl-formamide / 1 h / 125 - 130 °C View Scheme
Multi-step reaction with 3 steps 1.1: potassium hydroxide / ethanol / 2 h / Reflux 1.2: 2 h / Reflux 1.3: 0.17 h / Reflux 2.1: tin(IV) chloride / chloroform / 20 °C / Cooling with ice 3.1: ethanethiol; sodium hydride / N,N-dimethyl-formamide / 3 h / 110 °C View Scheme

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:60 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1477-19-6

Chemistry

Molecular Structure of Benzarone (CAS NO. 1477-19-6):

EINECS: 216-026-2
IUPAC Name: (2-Ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone
Molecular Formula: C₁₇H₁₄O₃
Molecular Weight: 266.291260 g/mol
XLogP3: 4.3
H-Bond Donor: 1
H-Bond Acceptor: 3
Canonical SMILES: CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)O
InChI: InChI=1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3
InChIKey: RFRXIWQYSOIBDI-UHFFFAOYSA-N
Index of Refraction: 1.638
Molar Refractivity: 77.61 cm³
Molar Volume: 215.7 cm³
Surface Tension: 50.9 dyne/cm
Density: 1.234 g/cm³
Flash Point: 240.2 °C
Enthalpy of Vaporization: 76.49 kJ/mol
Boiling Point: 473.6 °C at 760 mmHg
Vapour Pressure: 1.36E-09 mmHg at 25 °C
Water Solubility of Benzarone (CAS NO. 1477-19-6): 17.07 mg/L at 25 °C

Toxicity Data With Reference

ipr-mus LD50:200 mg/kg

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie, 154 (1965),94.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. A flammable liquid. When heated to decomposition it emits acrid and irritating smoke and fumes. See also KETONES.

Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

Specification

Benzarone with cas registry number of 1477-19-6 is also known as 2-Ethyl-3-(4-hydroxybenzoyl)benzofuran ; 2-Ethyl-3-(p-hydroxybenzoyl)benzofuran ; 2-Ethyl-3-benzofuranyl p-hydroxyphenyl ketone ; 2-Ethyl-3-(4'-hydroxybenzoyl)benzofuran ; 2-Ethyl-4'-hydroxy-3-benzoylbenzofuran ; 5-18-02-00334 (Beilstein Handbook Reference) ; Benzarona ; Benzarona [INN-Spanish] ; Benzarone [INN:DCF] ; Benzarone ; Benzaronum ; Benzaronum [INN-Latin] ; Benzofuran, (2-ethyl-3-(4'-hydroxybenzoyl)) ; Ethyl-2 (hydroxy-4 benzoyl)-3 benzofuranne ; Ethyl-2 (hydroxy-4 benzoyl)-3 benzofuranne [French] ; Fragivix ; L 2197 ; L 2197-Labaz ; Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxyphenyl)- ; NSC 82134 ; UNII-23ZW4BG89C ; Vasoc ; Venagil ; Ketone, 2-ethyl-3-benzofuranyl p-hydroxyphenyl .