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| CAS No.: | 14913-33-8 |
|---|---|
| Name: | trans-Dichlorodiamineplatinum(II) |
| Article Data: | 129 |
| Molecular Structure: | |
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| Formula: | Cl2H6N2Pt |
| Molecular Weight: | 300.047 |
| Synonyms: | trans-Platinumdiammine dichloride;Platinum,diamminedichloro-, trans- (8CI);NSC 131558;Transplatin;trans-DDP;trans-Diaminedichloroplatinum;trans-Diamminedichloroplatinum;trans-Diamminedichloroplatinum(II);trans-Dichlorodiamineplatinum(II);trans-Dichlorodiammine platinum;trans-Dichlorodiammineplatinum(II);trans-Platinum(II) ammonium chloride; |
| EINECS: | 238-980-9 |
| Density: | 3.746 g/cm3 |
| Melting Point: | 340 °C (dec.)(lit.) |
| Solubility: | Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water. |
| Appearance: | Yellow Powder or Crystal |
| Hazard Symbols: |
 T;  Xn
|
| Risk Codes: | 45-25-41-68-42/43-40-23/24/25 |
| Safety: | 53-26-39-45-36/37-24-23 |
| Transport Information: | UN 3288 6.1/PG 2 |
| PSA: | 6.48000 |
| LogP: | 2.02430 |
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Specification
The CAS registry number of trans-Dichlorodiammineplatinum(ii) is 14913-33-8. The IUPAC name is Diamminedichloroplatinum (trans). Its EINECS registry number is 238-980-9. In addition, the molecular formula is Cl2H6N2Pt and the molecular weight is 300.04. It is a kind of yellow powder or crystal and ineffective as antineoplastic agent. What's more, it should be stored in sealed container, and put them in a cool and dry place.
When you are using trans-Dichlorodiammineplatinum(ii), please be cautious about it as the following:
It is toxic if swallowed and toxic by inhalation, in contact with skin and if swallowed. And it has risk of serious damage to eyes and may cause cancer. In addition, it is possible risk of irreversible effects. But there is limited evidence of a carcinogenic effect. You should avoid exposure-obtain special instruction before use. During using it, wear suitable protective clothing, gloves and eye/face protection and avoid contact with skin. Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer). In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. And in case of accident or if you feel unwell, seek medical advice immediately (show label where possible). Although it is slightly harmful to the water, you can not let a large number of this products contact with the groundwater, the waterway or sewage system. If without government permission, do not put this material into surroundings.
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 27mg/kg (27mg/kg) | Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972. |