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151-50-8

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Basic Information
CAS No.: 151-50-8
Name: Potassium cyanide
Molecular Structure:
Molecular Structure of 151-50-8 (Potassium cyanide)
Formula: KCN
Molecular Weight: 65.12
Synonyms: Potassiumcyanide (8CI);Cyanide of potassium;Hydrocyanic acid, potassium salt;Kalium cyanid;Potassium cyanide (K(CN));
EINECS: 205-792-3
Density: 1.00 g/mL at 20 °C
Melting Point: 634.5 °C
Boiling Point: 1625 °C
Flash Point: 1625°C
Solubility: Soluble in water
Appearance: White crystalline solid
Hazard Symbols: DangerousN, VeryT+
Risk Codes: 26/27/28-32-50/53
Safety: 7-28-29-45-60-61
Transport Information: UN 1680 6.1/PG 1
PSA: 23.79000
LogP: 0.01678
Synthetic route
74-90-8

hydrogen cyanide

917-58-8

potassium ethoxide

151-50-8

potassium cyanide

74-90-8

hydrogen cyanide

151-50-8

potassium cyanide

Conditions
ConditionsYield
With potassium hydroxide; ethanol
590-28-3

potassium cyanate

151-50-8

potassium cyanide

Conditions
ConditionsYield
at 700℃;
at 900℃;
333-20-0

potassium thioacyanate

497-19-8

sodium carbonate

151-50-8

potassium cyanide

86-74-8

9H-carbazole

KOH

KOH

151-50-8

potassium cyanide

Conditions
ConditionsYield
anschl. Gluehen;
anschl. Gluehen;
108-80-5

cyanuric acid

potassium

potassium

151-50-8

potassium cyanide

Conditions
ConditionsYield
Schmelzen mit viel Kalium;

N-(benzo[1,3]dioxol-5-yl-cyano-methyl)-glycin-ethyl ester

alcoholic KOH-solution

alcoholic KOH-solution

A

N-piperonylidene-glycine

B

151-50-8

potassium cyanide

99-11-6

citrazinic acid

potassium hydroxide

potassium hydroxide

A

151-50-8

potassium cyanide

B

144-62-7

oxalic acid

Conditions
ConditionsYield
beim Schmelzen;
859802-57-6

2,6-diethyl-5-methyl-3H-pyrimidin-4-one

potassium hydroxide

potassium hydroxide

A

7664-41-7

ammonia

B

151-50-8

potassium cyanide

C

64-19-7

acetic acid

D

802294-64-0

propionic acid

Conditions
ConditionsYield
beim Schmelzen;
69-93-2

uric Acid

potassium hydroxide

potassium hydroxide

A

590-28-3

potassium cyanate

B

151-50-8

potassium cyanide

C

potassium carbonate

potassium carbonate

Conditions
ConditionsYield
im bedeckten Tiegel;
69-93-2

uric Acid

potassium hydroxide

potassium hydroxide

A

7664-41-7

ammonia

B

151-50-8

potassium cyanide

C

583-52-8

potassium oxalate

D

potassium carbonate

potassium carbonate

556-64-9

methyl thiocyanate

alcoholic KOH-solution

alcoholic KOH-solution

A

624-92-0

Dimethyldisulphide

B

7664-41-7

ammonia

C

151-50-8

potassium cyanide

D

potassium carbonate

potassium carbonate

19159-68-3

dipicryl-diazene

diluted KOH-solution

diluted KOH-solution

A

151-50-8

potassium cyanide

B

88-89-1

2,4,6-Trinitrophenol

C

68683-32-9

2,2',4,4',6,6'-hexanitrohydrazobenzene

D

potassium nitrite

potassium nitrite

60-29-7

diethyl ether

506-78-5

cyanogen iodide

KOH

KOH

151-50-8

potassium cyanide

506-68-3

bromocyane

64-17-5

ethanol

KOH

KOH

151-50-8

potassium cyanide

506-78-5

cyanogen iodide

64-17-5

ethanol

KOH

KOH

151-50-8

potassium cyanide

60-29-7

diethyl ether

506-68-3

bromocyane

67-66-3

chloroform

KOH

KOH

151-50-8

potassium cyanide

506-78-5

cyanogen iodide

67-66-3

chloroform

KOH

KOH

151-50-8

potassium cyanide

506-68-3

bromocyane

KOH

KOH

151-50-8

potassium cyanide

506-78-5

cyanogen iodide

KOH

KOH

151-50-8

potassium cyanide

460-19-5

ethanedinitrile

potassium

potassium

151-50-8

potassium cyanide

460-19-5

ethanedinitrile

potassium carbonate

potassium carbonate

A

590-28-3

potassium cyanate

B

151-50-8

potassium cyanide

Conditions
ConditionsYield
in der Rotglut;
542-90-5

ethyl isothiocyanate

aqueous KOH-solution

aqueous KOH-solution

A

110-81-6

Diethyl disulfide

B

590-28-3

potassium cyanate

C

151-50-8

potassium cyanide

Conditions
ConditionsYield
at 100℃; im zugeschmolzenen Rohr;
14752-58-0

trichloroacetonitrile

concentrated KOH-solution

concentrated KOH-solution

A

7664-41-7

ammonia

B

151-50-8

potassium cyanide

13369-04-5

Cyan-imidoameisensaeureethylester

alcoholic potash

alcoholic potash

A

151-50-8

potassium cyanide

B

potassium fulminate

460-19-5

ethanedinitrile

aqueous KOH-solution

aqueous KOH-solution

A

151-50-8

potassium cyanide

B

potassium fulminate

624-79-3

ethyl isocyanide

potassium amide

A

151-50-8

potassium cyanide

B

75-04-7

ethylamine

624-79-3

ethyl isocyanide

potassium amide

liquid.ammonia

liquid.ammonia

A

151-50-8

potassium cyanide

B

75-04-7

ethylamine

Conditions
ConditionsYield
at 80℃;
460-19-5

ethanedinitrile

aqueous KOH-solution

aqueous KOH-solution

A

590-28-3

potassium cyanate

B

7664-41-7

ammonia

C

151-50-8

potassium cyanide

D

azulminic acid

azulminic acid

Conditions
ConditionsYield
Produkt5: CO2;
460-19-5

ethanedinitrile

K2CO3

K2CO3

A

590-28-3

potassium cyanate

B

124-38-9

carbon dioxide

C

151-50-8

potassium cyanide

D

paracyan

paracyan

Conditions
ConditionsYield
at 190 - 370℃; Produkt 5: Stickstoff;
111-83-1

1-bromo-octane

151-50-8

potassium cyanide

2243-27-8

nonanonitrile

Conditions
ConditionsYield
Sucrose-ethyleneoxide adducts In acetonitrile at 83℃; for 24h; Product distribution; further catalysts: PEG, DB18K6; further objects of study: phase-transfer catalysis; further solvents: toluene/H2O;100%
tetraoctyl ammonium bromide In water; toluene at 90℃; for 24h; Product distribution; other phase-transfer catalysts, time;99%
tetraoctyl ammonium bromide In water; toluene at 90℃; for 24h;99%
151-50-8

potassium cyanide

98-86-2

acetophenone

20102-12-9

2-hydroxy-2-phenylpropionitrile

Conditions
ConditionsYield
Stage #1: potassium cyanide; acetophenone With 18-crown-6 ether In dichloromethane at 20℃; for 4h;
Stage #2: With hydrogenchloride In tetrahydrofuran; dichloromethane at 0 - 20℃; for 2h;
100%
Stage #1: potassium cyanide; acetophenone With tetrachlorosilane In acetonitrile at 60 - 70℃; for 5h;
Stage #2: With sodium hydrogencarbonate In water; acetonitrile Further stages.;
82%
With hydrogenchloride
151-50-8

potassium cyanide

402-23-3

1-bromomethyl-3-trifluoromethylbenzene

2338-76-3

3-trifluoromethylphenylacetonitrile

Conditions
ConditionsYield
In ethanol; water for 1.5h; Heating / reflux;100%
In dimethyl sulfoxide
500-22-1

3-pyridinecarboxaldehyde

151-50-8

potassium cyanide

17604-74-9

2-hydroxy-2-(pyridin-3-yl)acetonitrile

Conditions
ConditionsYield
With water; acetic acid at 5 - 10℃; for 2h;100%
With hydrogenchloride
With acetic acid In water for 18h; Ambient temperature;
75-77-4

chloro-trimethyl-silane

3900-45-6

6-methoxy-2-acetylnaphthalene

151-50-8

potassium cyanide

107727-73-1

2-(6-methoxy-2-naphthyl)-2-(trimethylsilyloxy)propiononitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 60℃; for 13.5h;100%
71629-66-8

(+)-<(1S,2S)-1-Hydroxy-2-methyl-3-oxo-cyclopent-2-yl>-essigsaeure-γ-lacton

151-50-8

potassium cyanide

98926-41-1

(1S,2S)-6-Cyano-6-hydroxy-5-methyl-2-oxa-bicyclo<3.3.0>octan-3-on

Conditions
ConditionsYield
In water; acetic acid at 5℃; for 20h;100%
124-13-0

Octanal

593-51-1

methylamine hydrochloride

151-50-8

potassium cyanide

112101-12-9

2-Methylamino-nonanenitrile

Conditions
ConditionsYield
With aluminum oxide In acetonitrile at 50℃; for 22h; ultrasound;100%
51991-03-8

5-anti-Chloro-6-syn-cyanobicyclo<2.1.1>hexene

151-50-8

potassium cyanide

72431-16-4

endo,endo-3,5-Dicyanotricyclo<2.2.0.02.6>hexane

Conditions
ConditionsYield
In water; acetonitrile for 30h; Ambient temperature;100%
841-95-2

9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-one

151-50-8

potassium cyanide

133308-74-4

2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2-carbonitrile

Conditions
ConditionsYield
With ammonia; acetic acid In water at 40℃; for 25h; Irradiation; irrad. with ultrasound;100%
151-50-8

potassium cyanide

1-Chloromethyl-7-methoxy-1,4,4-trimethyl-isothiochroman

128276-86-8

7-methoxy-1,4,4-trimethylisothiochroman-1-ylacetonitril

Conditions
ConditionsYield
In ethanol; water for 3h; Heating;100%
151-50-8

potassium cyanide

100-39-0

benzyl bromide

140-29-4

phenylacetonitrile

Conditions
ConditionsYield
Sucrose-ethyleneoxide adducts In acetonitrile at 20℃; for 8h; Product distribution; further catalysts: PEG, DB18K6; further objects of study: phase-transfer catalysis; further solvents: toluene/H2O;100%
With water; Aliquat 336 for 2h; Ambient temperature;97%
With poly(ethylene glycol)-supported tetrabutylamminium bromide In water at 25℃; for 2h; Substitution;97%
151-50-8

potassium cyanide

142-04-1

aniline hydrochloride

459-57-4

4-fluorobenzaldehyde

124573-71-3

2-(4-fluorophenyl)-2-(phenylamino) acetonitrile

Conditions
ConditionsYield
In ethanol; water 1.) 1 h cooling; 2.) 20 h room temperature;100%
151-50-8

potassium cyanide

<5-(Diphenylmethylen)-1,3-cyclopentadien-1-yl>dimethylsulfonium-perchlorat

1-(Cyandiphenylmethyl)-2-(dimethylsulfonio)cyclopentadienid

Conditions
ConditionsYield
In methanol at 0℃; for 0.25h;100%
151-50-8

potassium cyanide

<5-(Diphenylmethylen)-1,3-cyclopentadien-1-yl>diphenylsulfonium-perchlorat

1-(Cyandiphenylmethyl)-2-(diphenylsulfonio)cyclopentadienid

Conditions
ConditionsYield
In methanol at 0℃; for 0.25h;100%
151-50-8

potassium cyanide

<5-(Diphenylmethylen)-1,3-cyclopentadien-1-yl>bis(4-methylphenyl)sulfonium-perchlorat

1--2-(cyandiphenylmethyl)cyclopentadienid

Conditions
ConditionsYield
In methanol at 0℃; for 0.25h;100%
151-50-8

potassium cyanide

104700-37-0

ethyl [L-(trans)]-4-[(t-butoxycarbonyl)amino]-2-pentenoate

(S)-4-tert-Butoxycarbonylamino-3-cyano-pentanoic acid ethyl ester

Conditions
ConditionsYield
With 18-crown-6 ether In acetonitrile for 24h; Ambient temperature;100%
151-50-8

potassium cyanide

161363-80-0

2-Benzyl-3-(bromomethyl)-1,4-dimethoxynaphthalene

161363-81-1

2-Benzyl-3-(cyanomethyl)-1,4-dimethoxynaphthalene

Conditions
ConditionsYield
In 1,4-dioxane; water for 10h; Heating;100%
151-50-8

potassium cyanide

60211-89-4, 63616-13-7, 93424-19-2

trans-1-iodo-2-isothiocyanatocyclohexane

77469-22-8

2-cyano-cis-3a,4,5,6,7,7a-hexahydrobenzothiazole

Conditions
ConditionsYield
With 18-crown-6 ether In chloroform; water for 92h; Heating;100%
151-50-8

potassium cyanide

114200-84-9

4'-(chloromethyl)dispirobis<1,3>dioxole-6',1''-cyclohexane>

114200-85-0

dispirobis<1,3>dioxole-6',1''-cyclohexane>-4'-acetonitrile

Conditions
ConditionsYield
With 18-crown-6 ether In acetonitrile for 5h; Heating;100%
151-50-8

potassium cyanide

120667-42-7

diethyl <<3-(bromomethyl)phenyl>methyl>phosphonate

140151-14-0

diethyl <<3-(cyanomethyl)phenyl>methyl>phosphonate

Conditions
ConditionsYield
With sodium iodide In water; acetone at 50℃; for 48h;100%
151-50-8

potassium cyanide

108228-81-5

4-(diethoxyphosphorylmethyl)-1-bromomethyl-phenyl

135335-15-8

diethyl <<4-(cyanomethyl)phenyl>methyl>phosphonate

Conditions
ConditionsYield
With sodium iodide In water; acetone at 50℃; for 48h;100%
151-50-8

potassium cyanide

3-(2,6-Dimethylphenyl)-4-methyl-5-acetyl-2-imino-thiazolin Hydrobromid

2-Aminocarbonylimino-3-(2,6-dimethylphenyl)-4-methyl-5-acetyl-thiazolin

Conditions
ConditionsYield
In water100%
151-50-8

potassium cyanide

<5-(Diphenylmethylen)-1,3-cyclopentadien-1-yl>methylphenylsulfonium-perchlorat

1-(Cyandiphenylmethyl)-2-(methylphenylsulfonio)cyclopentadienid

Conditions
ConditionsYield
In methanol at 0℃; for 0.25h;100%
151-50-8

potassium cyanide

ethyl 8,9-bis(4-methoxyphenyl)-10,10-dimethyl-5-oxotricyclo<5.2.1.02,6>deca-3,8-diene-2-carboxylate

(3aS,4R,7S,7aR)-3-Cyano-5,6-bis-(4-methoxy-phenyl)-8,8-dimethyl-1-oxo-1,2,3,4,7,7a-hexahydro-4,7-methano-indene-3a-carboxylic acid ethyl ester

Conditions
ConditionsYield
With ammonium chloride In water; N,N-dimethyl-formamide at 100℃; for 4.5h;100%
151-50-8

potassium cyanide

75-07-0

acetaldehyde

3535-04-4

2-<(1-methyl-2-phenylethyl)amino>propanenitrile

Conditions
ConditionsYield
With sodium hydrogensulfite In methanol; water Ambient temperature;100%
593-51-1

methylamine hydrochloride

151-50-8

potassium cyanide

98-86-2

acetophenone

112101-15-2

2-methylamino-2-phenyl-propionitrile

Conditions
ConditionsYield
With aluminum oxide In acetonitrile at 50℃; for 24h; ultrasound;100%
151-50-8

potassium cyanide

591-31-1

3-methoxy-benzaldehyde

53313-94-3

m-methoxymandelonitrile

Conditions
ConditionsYield
Stage #1: 3-methoxy-benzaldehyde With hydrogenchloride; sodium sulfite In tetrahydrofuran; water at 20℃; for 0.166667h;
Stage #2: potassium cyanide In tetrahydrofuran; water for 0.5h;
100%
With sodium hydrogensulfite 1) H2O, 40 deg C, 0.5 h, 2) H2O, 0 deg C, 1 h; Multistep reaction;
With acetic acid In water
With hydrogenchloride; sodium sulfite In tetrahydrofuran at 20℃; for 0.5h;
50-00-0

formaldehyd

151-50-8

potassium cyanide

103-67-3

benzyl-methyl-amine

14321-25-6

(N-benzyl-N-methylamino)acetonitrile

Conditions
ConditionsYield
With hydrogenchloride for 16h; Ambient temperature;100%
151-50-8

potassium cyanide

(1S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-7-hydroxy-4-oxo-2,8-dioxa-bicyclo[3.2.1]octane-5-carboxylic acid

(1S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4-cyano-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-2,8-dioxa-bicyclo[3.2.1]octane-5-carboxylic acid

Conditions
ConditionsYield
With acetic acid In methanol; isopropyl alcohol100%
52421-93-9

(2Z)-3-methyl-2-penten-4-ynal

151-50-8

potassium cyanide

(Z)-1-cyano-3-methylpent-2-en-4-yn-1-ol

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether; water 30 min, 0 deg C; 2 h, 20 deg C;100%
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Specification

The IUPAC name of Potassium cyanide is potassium cyanide. With the CAS registry number 151-50-8, it is also named as Hydrocyanic acid, potassium salt. The product's categories are Inorganics; ACS Grade; Essential Chemicals; Routine Reagents; Masking AgentsAnalytical Reagents for General Use; Complexometric Titration (IDRANAL); O-P, Puriss p.a. ACS; Puriss p.a. ACS; Titration; Masking Agents; O-P, Puriss p.a.; Puriss p.a., and the other registry numbers are 133708-36-8; 15745-74-1; 60195-52-0. Besides, it is white granular powder or crystals, which should be sealed in a cool and dry warehouse. In addition, its molecular formula is CKN and molecular weight is 65.12.

The other characteristics of this product can be summarized as: (1)EINECS: 205-792-3; (2)H-Bond Donor: 0; (3)H-Bond Acceptor: 2; (4)Rotatable Bond Count: 0; (5)Exact Mass: 64.966781; (6)MonoIsotopic Mass: 64.966781; (7)Topological Polar Surface Area: 23.8; (8)Heavy Atom Count: 3; (9)Complexity: 12.8; (10)Density: 1.52 g/cm3; (11)Melting point: 634.5 °C; (12)Boiling point: 1625 °C; (13)Flash Point: 1625 °C; (14)Solubility in water: 71.6 g/100 ml (25 °C).

Preparation of Potassium cyanide: this chemical can be prepared by the treatment of Hydrogen cyanide with Potassium hydroxide:
HCN + KOH → KCN + H2O

Uses of Potassium cyanide: it is widely used in organic synthesis for the preparation of nitriles and carboxylic acids. It is also used in electroplating, such as jewelry for chemical gilding and buffing. And this product has been used as a killing agent in collecting jars by entomologists. Additionally, this chemical can form water-soluble salts from gold metal in the presence of air in gold mining:
4 Au + 8 KCN + O2 + 2 H2O → 4 K[Au(CN)2] + 4 KOH

When you are using this chemical, please be cautious about it as the following: it is very toxic by inhalation, in contact with skin and if swallowed. And it would liberate very toxic gas in contact with acid. Please keep container tightly closed and do not empty into drains. After contact with skin, you should wash immediately with plenty of soap-suds. Moreover, it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) And this material and its container must be disposed of as hazardous waste. Please avoid release to the environment and refer to special instructions / safety data sheets.

People can use the following data to convert to the molecule structure.
(1)Canonical SMILES: [C-]#N.[K+]
(2)InChI: InChI=1S/CN.K/c1-2;/q-1;+1
(3)InChIKey: NNFCIKHAZHQZJG-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 2200ug/kg (2.2mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 316, 1936.
dog LD50 subcutaneous 6mg/kg (6mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Archiv fuer Toxikologie. Vol. 21, Pg. 89, 1965.
dog LDLo intravenous 5mg/kg (5mg/kg)   "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973.
frog LDLo subcutaneous 60mg/kg (60mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
guinea pig LDLo intraarterial 5mg/kg (5mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo intraperitoneal 8mg/kg (8mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927.
guinea pig LDLo intravenous 5mg/kg (5mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo subcutaneous 8mg/kg (8mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927.
human LDLo oral 2857ug/kg (2.857mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 191, 1969.
man TDLo oral 13699ug/kg (13.699mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA
Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 121, 1987.
mouse LD50 intraperitoneal 5991ug/kg (5.991mg/kg)   Pesticide Biochemistry and Physiology. Vol. 2, Pg. 95, 1972.
mouse LD50 intravenous 2600ug/kg (2.6mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
mouse LD50 oral 8500ug/kg (8.5mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 161, Pg. 163, 1968.
mouse LD50 subcutaneous 6500ug/kg (6.5mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 1057, 1958.
pigeon LD50 intramuscular 4mg/kg (4mg/kg)   Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
rabbit LD50 intramuscular 3256ug/kg (3.256mg/kg)   Journal of the American College of Toxicology. Vol. 1(3), Pg. 120, 1982.
rabbit LD50 intraperitoneal 3972ug/kg (3.972mg/kg) BLOOD: OTHER CHANGES Toxicologist. Vol. 3, Pg. 64, 1983.
rabbit LD50 ocular 7870ug/kg (7.87mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 2, Pg. 119, 1983.
rabbit LD50 oral 5mg/kg (5mg/kg)   "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973.
rabbit LD50 subcutaneous 4mg/kg (4mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
rat LD50 intraperitoneal 4mg/kg (4mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Applied Physiology. Vol. 32, Pg. 315, 1972.
rat LD50 intravenous 3600ug/kg (3.6mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Drug Development Research. Vol. 5, Pg. 225, 1985.
rat LD50 oral 5mg/kg (5mg/kg)   Archives of Toxicology. Vol. 54, Pg. 275, 1983.
rat LD50 subcutaneous 7814ug/kg (7.814mg/kg)   Archives of Toxicology, Supplement. Vol. 14, Pg. 231, 1991.
rat LDLo intramuscular 8mg/kg (8mg/kg)   "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973.
women TDLo oral 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
American Journal of Emergency Medicine. Vol. 1, Pg. 94, 1983.