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CAS No.: | 151-50-8 |
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Name: | Potassium cyanide |
Article Data: | 86 |
Molecular Structure: | |
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Formula: | KCN |
Molecular Weight: | 65.116 |
Synonyms: | Potassiumcyanide (8CI);Cyanide of potassium;Hydrocyanic acid, potassium salt;Kalium cyanid;Potassium cyanide (K(CN)); |
EINECS: | 205-792-3 |
Density: | 1.00 g/mL at 20 °C |
Melting Point: | 634.5 °C |
Boiling Point: | 1625 °C |
Flash Point: | 1625°C |
Solubility: | Soluble in water |
Appearance: | White crystalline solid |
Hazard Symbols: |
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Risk Codes: | 26/27/28-32-50/53 |
Safety: | 7-28-29-45-60-61 |
Transport Information: | UN 1680 6.1/PG 1 |
PSA: | 23.79000 |
LogP: | 0.01678 |
Conditions | Yield |
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With potassium hydroxide; ethanol |
Conditions | Yield |
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at 700℃; | |
at 900℃; |
Conditions | Yield |
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anschl. Gluehen; | |
anschl. Gluehen; |
Conditions | Yield |
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Schmelzen mit viel Kalium; |
Conditions | Yield |
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beim Schmelzen; |
2,6-diethyl-5-methyl-3H-pyrimidin-4-one
A
ammonia
B
potassium cyanide
C
acetic acid
D
propionic acid
Conditions | Yield |
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beim Schmelzen; |
Conditions | Yield |
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im bedeckten Tiegel; |
The IUPAC name of Potassium cyanide is potassium cyanide. With the CAS registry number 151-50-8, it is also named as Hydrocyanic acid, potassium salt. The product's categories are Inorganics; ACS Grade; Essential Chemicals; Routine Reagents; Masking AgentsAnalytical Reagents for General Use; Complexometric Titration (IDRANAL); O-P, Puriss p.a. ACS; Puriss p.a. ACS; Titration; Masking Agents; O-P, Puriss p.a.; Puriss p.a., and the other registry numbers are 133708-36-8; 15745-74-1; 60195-52-0. Besides, it is white granular powder or crystals, which should be sealed in a cool and dry warehouse. In addition, its molecular formula is CKN and molecular weight is 65.12.
The other characteristics of this product can be summarized as: (1)EINECS: 205-792-3; (2)H-Bond Donor: 0; (3)H-Bond Acceptor: 2; (4)Rotatable Bond Count: 0; (5)Exact Mass: 64.966781; (6)MonoIsotopic Mass: 64.966781; (7)Topological Polar Surface Area: 23.8; (8)Heavy Atom Count: 3; (9)Complexity: 12.8; (10)Density: 1.52 g/cm3; (11)Melting point: 634.5 °C; (12)Boiling point: 1625 °C; (13)Flash Point: 1625 °C; (14)Solubility in water: 71.6 g/100 ml (25 °C).
Preparation of Potassium cyanide: this chemical can be prepared by the treatment of Hydrogen cyanide with Potassium hydroxide:
HCN + KOH → KCN + H2O
Uses of Potassium cyanide: it is widely used in organic synthesis for the preparation of nitriles and carboxylic acids. It is also used in electroplating, such as jewelry for chemical gilding and buffing. And this product has been used as a killing agent in collecting jars by entomologists. Additionally, this chemical can form water-soluble salts from gold metal in the presence of air in gold mining:
4 Au + 8 KCN + O2 + 2 H2O → 4 K[Au(CN)2] + 4 KOH
When you are using this chemical, please be cautious about it as the following: it is very toxic by inhalation, in contact with skin and if swallowed. And it would liberate very toxic gas in contact with acid. Please keep container tightly closed and do not empty into drains. After contact with skin, you should wash immediately with plenty of soap-suds. Moreover, it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) And this material and its container must be disposed of as hazardous waste. Please avoid release to the environment and refer to special instructions / safety data sheets.
People can use the following data to convert to the molecule structure.
(1)Canonical SMILES: [C-]#N.[K+]
(2)InChI: InChI=1S/CN.K/c1-2;/q-1;+1
(3)InChIKey: NNFCIKHAZHQZJG-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | intravenous | 2200ug/kg (2.2mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 316, 1936. | |
dog | LD50 | subcutaneous | 6mg/kg (6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archiv fuer Toxikologie. Vol. 21, Pg. 89, 1965. |
dog | LDLo | intravenous | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
frog | LDLo | subcutaneous | 60mg/kg (60mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. | |
guinea pig | LDLo | intraarterial | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | intraperitoneal | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
guinea pig | LDLo | intravenous | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | subcutaneous | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
human | LDLo | oral | 2857ug/kg (2.857mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 191, 1969. | |
man | TDLo | oral | 13699ug/kg (13.699mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA | Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 121, 1987. |
mouse | LD50 | intraperitoneal | 5991ug/kg (5.991mg/kg) | Pesticide Biochemistry and Physiology. Vol. 2, Pg. 95, 1972. | |
mouse | LD50 | intravenous | 2600ug/kg (2.6mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
mouse | LD50 | oral | 8500ug/kg (8.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 161, Pg. 163, 1968. | |
mouse | LD50 | subcutaneous | 6500ug/kg (6.5mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 1057, 1958. | |
pigeon | LD50 | intramuscular | 4mg/kg (4mg/kg) | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. | |
rabbit | LD50 | intramuscular | 3256ug/kg (3.256mg/kg) | Journal of the American College of Toxicology. Vol. 1(3), Pg. 120, 1982. | |
rabbit | LD50 | intraperitoneal | 3972ug/kg (3.972mg/kg) | BLOOD: OTHER CHANGES | Toxicologist. Vol. 3, Pg. 64, 1983. |
rabbit | LD50 | ocular | 7870ug/kg (7.87mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 2, Pg. 119, 1983. |
rabbit | LD50 | oral | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
rabbit | LD50 | subcutaneous | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
rat | LD50 | intraperitoneal | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Applied Physiology. Vol. 32, Pg. 315, 1972. |
rat | LD50 | intravenous | 3600ug/kg (3.6mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Drug Development Research. Vol. 5, Pg. 225, 1985. |
rat | LD50 | oral | 5mg/kg (5mg/kg) | Archives of Toxicology. Vol. 54, Pg. 275, 1983. | |
rat | LD50 | subcutaneous | 7814ug/kg (7.814mg/kg) | Archives of Toxicology, Supplement. Vol. 14, Pg. 231, 1991. | |
rat | LDLo | intramuscular | 8mg/kg (8mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
women | TDLo | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | American Journal of Emergency Medicine. Vol. 1, Pg. 94, 1983. |