Products Categories
| CAS No.: | 1513-66-2 |
|---|---|
| Name: | 2,3-Difluoropyridine |
| Article Data: | 10 |
| Molecular Structure: | |
|
|
|
| Formula: | C5H3F2N |
| Molecular Weight: | 115.082 |
| Synonyms: | 2,3-Difluorpyridin; |
| Density: | 1.264 g/cm3 |
| Boiling Point: | 116.476 °C at 760 mmHg |
| Flash Point: | 24.244 °C |
| Hazard Symbols: |
 T, F, Xi
|
| Risk Codes: | 10-36/37/38 |
| Safety: | 26-36/37/39 |
| PSA: | 12.89000 |
| LogP: | 1.35980 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 211914-50-0N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride
- 89402-43-7
5-chloro-2,3-difluoropyridine
- 1513-66-2
2,3-difluoropyridine
| Conditions | Yield |
|---|---|
| With ammonium formate; acetic acid; palladium on activated charcoal at 25℃; for 6h; | 75% |
| palladium-carbon | |
| palladium-carbon |
- 110-86-1
pyridine
A
- 2344-10-7
perfluoro-N-ethylpyrrolidine
B
- 1513-66-2
2,3-difluoropyridine
C
- 700-16-3
Pentafluoropyridine
D
- 371-77-7
N,N-Bis(trifluoromethyl)amine
| Conditions | Yield |
|---|---|
| With caesium tetrafluorocobaltate(III) In gaseous matrix at 310℃; for 3.5h; Further byproducts given; | A 35.3% B 2.2% C 13.6% D 8.2% |
- 110-86-1
pyridine
A
- 1513-66-2
2,3-difluoropyridine
B
- 54471-09-9
4H,5H-heptafluoro-2-azahex-2(Z),4(E)-diene
C
- 54471-08-8
5H-decafluoro-2-azahex-2(Z)-ene
D
- 54471-05-5
undecafluoro-2-azahex-2(Z)-ene
| Conditions | Yield |
|---|---|
| With potassium tetrafluorocobaltate In gaseous matrix at 215 - 225℃; 1.) 3.5-4 h; 2.) 2 h; Further byproducts given; |
| Conditions | Yield |
|---|---|
| Stage #1: 2-chloro-3-aminopyridine With hexafluorophosphoric acid; sodium nitrite In water at 0℃; Stage #2: In xylene at 85℃; for 3h; Stage #3: With sodium hydrogencarbonate; triethylamine In water; xylene |
| Conditions | Yield |
|---|---|
| With silver(II) fluoride In acetonitrile at 20℃; for 1h; Mechanism; | 55 %Spectr. |
- 17282-04-1
2-chloro-3-fluoropyridine
- 1513-66-2
2,3-difluoropyridine
| Conditions | Yield |
|---|---|
| With tetramethylammonium fluoride In dimethyl sulfoxide at 80℃; for 24h; Inert atmosphere; Sealed tube; | 65 %Spectr. |
- 1513-66-2
2,3-difluoropyridine
- 887266-57-1
3-fluoro-2-hydrazinylpyridine
| Conditions | Yield |
|---|---|
| With hydrazine hydrate at 120℃; for 1h; | 93% |
| Conditions | Yield |
|---|---|
| Stage #1: 2,3-difluoropyridine With hydrazine hydrate In ethanol for 3h; Reflux; Stage #2: ethyl (ethoxymethylene)cyanoacetate In ethanol Reflux; | 91% |
| Conditions | Yield |
|---|---|
| With potassium carbonate In dimethyl sulfoxide at 150℃; for 12h; Inert atmosphere; | 90% |
| With potassium carbonate In dimethyl sulfoxide at 150℃; for 12h; Inert atmosphere; | 85% |
- 1513-66-2
2,3-difluoropyridine
| Conditions | Yield |
|---|---|
| With water; caesium carbonate In dimethyl sulfoxide at 110℃; for 12h; | 90% |
| With water; caesium carbonate In dimethyl sulfoxide at 110℃; for 12h; | 90% |
What can I do for you?
Get Best Price
Specification
The 2,3-Difluoropyridine, with the CAS registry number 1513-66-2, is also known as Pyridine, 2,3-difluoro-. And the molecular formula of this chemical is C5H3F2N. It belongs to the following product categories: Fluorin-contained pyridine series; Pyridine; Pyridines.
The physical properties of 2,3-Difluoropyridine are as following: (1)ACD/LogP: 1.30; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.299; (4)ACD/LogD (pH 7.4): 1.299; (5)ACD/BCF (pH 5.5): 5.717; (6)ACD/BCF (pH 7.4): 5.717; (7)ACD/KOC (pH 5.5): 121.23; (8)ACD/KOC (pH 7.4): 121.23; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 12.89 Å2; (13)Index of Refraction: 1.447; (14)Molar Refractivity: 24.332 cm3; (15)Molar Volume: 91.077 cm3; (16)Polarizability: 9.646×10-24cm3; (17)Surface Tension: 31.445 dyne/cm; (18)Density: 1.264 g/cm3; (19)Flash Point: 24.244 °C; (20)Enthalpy of Vaporization: 34.012 kJ/mol; (21)Boiling Point: 116.476 °C at 760 mmHg; (22)Vapour Pressure: 21.635 mmHg at 25°C.
You should be cautious while dealing with this chemical. It is a kind of flammable chemical which irritates eyes, respiratory system and skin. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.
You can still convert the following datas into molecular structure:
(1)SMILES: c1cc(c(nc1)F)F
(2)InChI: InChI=1/C5H3F2N/c6-4-2-1-3-8-5(4)7/h1-3H
(3)InChIKey: OGVLEPMNNPZAPS-UHFFFAOYAJ