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Basic Information
CAS No.: 152-47-6
Name: Sulfalen
Molecular Structure:
Molecular Structure of 152-47-6 (Sulfalen)
Formula: C11H12N4O3S
Molecular Weight: 280.307
Synonyms: Benzenesulfonamide,4-amino-N-(3-methoxypyrazinyl)- (9CI);Sulfanilamide, N1-(3-methoxypyrazinyl)-(8CI);2-Sulfanilamido-3-methoxypyrazine;3-Methoxy-2-sulfapyrazine;3-Methoxypyrazinesulfanilamide;AS 18908;Dalysep;
EINECS: 205-804-7
Density: 1.465 g/cm3
Melting Point: 174~178 °C
Boiling Point: 488.6 °C at 760 mmHg
Flash Point: 249.3 °C
Solubility: Hardly soluble in water, slightly soluble in ethanol, ethyl ether and propyl ether
Appearance: White or slightly yellow crystal powder
Hazard Symbols: Xi
Risk Codes: R36/37/38
PSA: 115.58000
LogP: 2.60320
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    Benzenesulfonamide,4-amino-N-(3-methoxy-2-pyrazinyl)-

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Chemistry

Product Name:Sulfalen
The MF of Sulfalen(152-47-6) is C11H12N4O3S.

                               
The MW of Sulfalen(152-47-6) is 280.3.
Synonyms:n1-(3-methoxy-2-pyrazinyl)sulfanilamide;sulfalen;SULFALENE;SULFAMETHOXYPYRAZINE;2-(p-aminobenzenesulfanamide)-3-methoxypyrazine;3-methoxy-2-sulfanilamidopyrazine;2-(p-aminobenzenesulfonamido)-3-methoxypyrazine
EINECS: 205-804-7 
Mol File: 152-47-6.mol
Surface Tension: 75 dyne/cm 
Density: 1.465 g/ml 
Flash Point: 249.3 °C 
Enthalpy of Vaporization: 75.47 kJ/mol 
Boiling Point: 488.6 °C at 760 mmHg 
Vapour Pressure: 1.07E-09 mmHg at 25°C 
CAS DataBase Reference: 152-47-6(CAS DataBase Reference) 

Uses

The Sulfalen(152-47-6) is used for respiratory, urinary and intestinal infections, chronic bronchitis, malignant disease and leprosy, Deng Jun effective.

Toxicity Data With Reference

1.   

sln-asn 1 g/L

   MUREAV    Mutation Research. 26 (1974),159.
2.   

orl-rat LD50:2739 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),459.
3.   

scu-rat LD50:2120 mg/kg

   NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),390.
4.   

ivn-rat LD50:1790 mg/kg

   NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),390.
5.   

orl-mus LD50:1292 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 127 (1960),58.
6.   

scu-mus LD50:1590 mg/kg

   NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),390.
7.   

ivn-mus LD50:893 mg/kg

   AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 127 (1960),58.

Safety Profile

Moderately toxic by ingestion, subcutaneous, and intravenous routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. An antibacterial agent. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also SULFONATES.