CAS No.163680-77-1,Pazufloxacin mesilate Suppliers

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Basic Information

Molecular Structure:
CAS No.:	163680-77-1
Name:	Pazufloxacin mesilate

Formula:	C₁₆H₁₅FN₂O₄.CH₄O₃S
Molecular Weight:	414.41
Synonyms:	(-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-;
EINECS:	634-946-6
Melting Point:	>255 °C (dec.)
Boiling Point:	531.5 °C at 760 mmHg
Flash Point:	275.2 °C
Appearance:	crystalline solid
Hazard Symbols:	Xi,C,F
Risk Codes:	36/37/38-34-11
Safety:	26-45-36/37/39-16
PSA:	157.30000
LogP:	3.02510

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Specification

The Pazufloxacin mesilate, with the CAS registry number 163680-77-1, is also known as 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-. It belongs to the product categories of API; Intermediates & Fine Chemicals; Pharmaceuticals; Amines; Aromatics; Chiral Reagents. This chemical's molecular formula is C₁₆H₁₅FN₂O₄^.CH₄O₃S and molecular weight is 414.41. What's more, its systematic name is (3S)-10-(1-Aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid methanesulfonate (1:1). This chemical is a total synthetic quinolone antibiotic used to treat diseases caused by a variety of bacterial infections.

Physical properties of Pazufloxacin mesilate are: (1)ACD/LogP: 0.6; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.90; (4)ACD/LogD (pH 7.4): -2.90; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 7 #H ; (10)bond donors: 2; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 109.36 Å².

When you are using this chemical, please be cautious about it as the following:
This chemical is highly flammable, so you should keep it away from sources of ignition - No smoking. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need to wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, you should seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: O=S(=O)(O)C.Fc3cc1c2N(/C=C(\C1=O)C(=O)O)[C@H](COc2c3C4(N)CC4)C
(2)Std. InChI: InChI=1S/C16H15FN2O4.CH4O3S/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22;1-5(2,3)4/h4-5,7H,2-3,6,18H2,1H3,(H,21,22);1H3,(H,2,3,4)/t7-;/m0./s1
(3)Std. InChIKey: UDHGFPATQWQARM-FJXQXJEOSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	521mg/kg (521mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.
monkey	LDLo	intravenous	520mg/kg (520mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.
rat	LDLo	intravenous	391mg/kg (391mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Japanese Journal of Antibiotics. Vol. 51, Pg. 583, 1998.