Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 1679 > 

1679-76-1

Products Categories

Basic Information
CAS No.: 1679-76-1
Name: Drofenine
Article Data: 7
Molecular Structure:
Molecular Structure of 1679-76-1 (Drofenine)
Formula: C20H31NO2
Molecular Weight: 317.472
Synonyms: Cyclohexaneaceticacid, a-phenyl-, 2-(diethylamino)ethylester (6CI,7CI,8CI);2-Diethylaminoethyl a-phenylcyclohexaneacetate;Adiphenine H;Cycloadiphene;Hexahydroadiphenine;Trasentine 6H;a-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethylester;a-Phenylcyclohexaneacetic acid2-(diethylamino)ethyl ester;2-(Diethylamino)ethyl cyclohexylphenylacetate;
Density: 1.018 g/cm3
Boiling Point: 417.4 °C at 760 mmHg
Flash Point: 124.6 °C
PSA: 29.54000
LogP: 4.23550
Related products
Hot Products
  • Display:default sort

    New supplier

  • Benzeneacetic acid, a-cyclohexyl-,2-(diethylamino)ethyl ester

  • Casno:

    1679-76-1

    Benzeneacetic acid, a-cyclohexyl-,2-(diethylamino)ethyl ester

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • Drofenine

  • Casno:

    1679-76-1

    Drofenine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

    Shanghai fine pharma co., Ltd. is a professional enterprise with chemical reagents and fine chemical products development, development and trade. The company has a sound research a

  • Shanghai Run-Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-21-31576854/57171705 / 57171706

    Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

       Inquiry Now

  • Drofenine

  • Casno:

    1679-76-1

    Drofenine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Drofenine

    Our company specializes in chemical products, including pharmaceutical intermediates, active pharmaceutical ingredients etc. High quality! High pur

  • U-Chemo Holding Co.,Limited

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-61558312

    Address:Dong Fang Road,

       Inquiry Now

  • Drofenine

  • Casno:

    1679-76-1

    Drofenine

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-200.0

    Appearance:powder Storage:Store in a cool,dry place and keep away from direct strong light Package:1kg.5kg,25kg,or customer requirements Transportation:by express courier or by sea and by air

    Shaanxi King Stone Enterprise Company Limited is a major company to export materials to several certain industry fields. Our company is headqu

  • Shaanxi King Stone Enterprise Company Limited

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-29-88353805,13609285751

    Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China

       Inquiry Now

  • Total:5 Page 1 of 1 1
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1679-76-1

Specification

The Benzeneacetic acid, a-cyclohexyl-,2-(diethylamino)ethyl ester, with the CAS registry number 1679-76-1, is also known as Drofenine. This chemical's molecular formula is C20H31NO2 and molecular weight is 317.47. What's more, its IUPAC name is called 2-(Diethylamino)ethyl 2-cyclohexyl-2-phenylacetate.

Physical properties about Benzeneacetic acid, a-cyclohexyl-,2-(diethylamino)ethyl ester are: (1)ACD/LogP: 5.59; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 2.58; (4)ACD/LogD (pH 7.4): 3.79; (5)ACD/BCF (pH 5.5): 10.3; (6)ACD/BCF (pH 7.4): 165.53; (7)ACD/KOC (pH 5.5): 25.84; (8)ACD/KOC (pH 7.4): 415.38; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 9; (12)Polar Surface Area: 29.54 Å2; (13)Index of Refraction: 1.519; (14)Molar Refractivity: 94.76 cm3; (15)Molar Volume: 311.7 cm3; (16)Surface Tension: 38.9 dyne/cm; (17)Density: 1.018 g/cm3; (18)Flash Point: 124.6 °C; (19)Enthalpy of Vaporization: 67.08 kJ/mol; (20)Boiling Point: 417.4 °C at 760 mmHg; (21)Vapour Pressure: 3.55E-07 mmHg at 25 °C.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(OCCN(CC)CC)C(c1ccccc1)C2CCCCC2
(2) InChI: InChI=1S/C20H31NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5,7-8,11-12,18-19H,3-4,6,9-10,13-16H2,1-2H3
(3) InChIKey: AGJBLWCLQCKRJP-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 500mg/kg (500mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS		 British Journal of Pharmacology and Chemotherapy. Vol. 14, Pg. 559, 1959.
rabbit LD subcutaneous > 200mg/kg (200mg/kg)   Acta Physiologica et Pharmacologica Neerlandica. Vol. 1, Pg. 4, 1950.
rabbit LDLo intravenous 40mg/kg (40mg/kg)   Acta Physiologica et Pharmacologica Neerlandica. Vol. 1, Pg. 4, 1950.
rat LD50 intravenous 37mg/kg (37mg/kg)   American Journal of Digestive Diseases. Vol. 18, Pg. 241, 1951.
rat LDLo oral 1600mg/kg (1600mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH		 Acta Physiologica et Pharmacologica Neerlandica. Vol. 1, Pg. 4, 1950.
rat LDLo subcutaneous 1600mg/kg (1600mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Acta Physiologica et Pharmacologica Neerlandica. Vol. 1, Pg. 4, 1950.