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1722-62-9

Basic Information
CAS No.: 1722-62-9
Name: Mepivacaine hydrochloride
Molecular Structure:
Molecular Structure of 1722-62-9 (Mepivacaine hydrochloride)
Formula: C15H22N2O.HCl
Molecular Weight: 282.81
Synonyms: Carbocaine monohydrochloride;Chlorocain;Meaverin;Mepicaton;Mepident;Mepivacaine monohydrochloride;Mepivastesin;Optocain;Scandicain;Scandonest;Mepivacaine HCL;2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI,8CI);Carbocaina;
EINECS: 217-023-9
Density:
Melting Point: 255-257oC (dec.)
Boiling Point: 383.1 °C at 760 mmHg
Flash Point: 185.5 °C
Solubility:
Appearance: White or off white crystalline powder
Hazard Symbols: HarmfulXn
Risk Codes: 22
Safety: 22-24/25
Transport Information:
PSA: 32.34000
LogP: 3.53910
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Chemistry

Product Name: Carbocaine hydrochloride (CAS NO.1722-62-9)


IUPAC Name: N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride
Molecular Formula: C15H23ClN2O
Molecular Weight: 282.8089 g/mol
Mol File: 1722-62-9.mol
Appearance: White or off white crystalline powder
Boiling point: 383.1 °C at 760 mmHg
Flash Point: 185.5 °C
Enthalpy of Vaporization: 63.16 kJ/mol
Vapour Pressure: 4.52E-06 mmHg at 25°C
H-Bond Donor: 2
H-Bond Acceptor:2

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 20mg/kg (20mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960.
guinea pig LD50 subcutaneous 94mg/kg (94mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960.
mouse LD50 implant 260mg/kg (260mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969.
mouse LD50 intraperitoneal 117mg/kg (117mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 40, Pg. 592, 1988.
mouse LD50 intravenous 32mg/kg (32mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960.
mouse LD50 subcutaneous 260mg/kg (260mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960.
rabbit LD50 implant 110mg/kg (110mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969.
rabbit LD50 intravenous 22mg/kg (22mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969.
rabbit LD50 subcutaneous 110mg/kg (110mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by subcutaneous, intravenous, subcutaneous, and implant routes. Experimental reproductive effects. An anesthetic. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Safety Information of Carbocaine hydrochloride (CAS NO.1722-62-9):
Hazard Codes: Xn
Risk Statements: 22 
22:  Harmful if swallowed
Safety Statements: 22-24/25
22:  Do not breathe dust 
24:  Avoid contact with skin 
25:  Avoid contact with eyes 

Specification

 Carbocaine hydrochloride ,its CAS NO. is 1722-62-9,the synonyms is (+-)-1-Methyl-2',6'-pipecoloxylidide monohydrochloride ; (1-Methyl-DL-piperidine-2-carboxylic acid)-2,6-dimethylanilide hydrochloride ; 1-Methyl-2',6'-pipecoloxylidide hydrochloride ; 1-Methyl-2',6'-pipecoloxylidide monohydrochloride ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride, (+-)- ; Arestocaine hydrochloride ; Carbocain ; Carbocaina ; Carbocaine ; Isocaine hydrochloride ; Meaverin ; Mepivacaine HCl ; Mepivacaine hydrochloride ; Mepivastesin ; Polocaine ; Polocaine-MPF ; Sabol ; Scandicain ; Scandicaine ; Scandinibsa ; Scandonest ; Scandonest Plain ; 2',6'-Pipecoloxylidide, 1-methyl -, monohydrochloride ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, hydrochloride (1:1) ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride .