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| CAS No.: | 1722-62-9 |
|---|---|
| Name: | Mepivacaine hydrochloride |
| Molecular Structure: | |
|
|
|
| Formula: | C15H22N2O.HCl |
| Molecular Weight: | 282.813 |
| Synonyms: | Carbocaine monohydrochloride;Chlorocain;Meaverin;Mepicaton;Mepident;Mepivacaine monohydrochloride;Mepivastesin;Optocain;Scandicain;Scandonest;Mepivacaine HCL;2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI,8CI);Carbocaina; |
| EINECS: | 217-023-9 |
| Melting Point: | 255-257oC (dec.) |
| Boiling Point: | 383.1 °C at 760 mmHg |
| Flash Point: | 185.5 °C |
| Appearance: | White or off white crystalline powder |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 22 |
| Safety: | 22-24/25 |
| PSA: | 32.34000 |
| LogP: | 3.53910 |
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| Conditions | Yield |
|---|---|
| In acetonitrile at 50℃; for 4h; Sonication; | 97% |
| Conditions | Yield |
|---|---|
| In acetonitrile at 50℃; for 4h; Sonication; | 95% |
- 1722-62-9
mepivacaine hydrochloride
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sodium hydrogencarbonate
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methyl iodide
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2-{[(2,6-Dimethylphenyl)amino]carbonyl}-1,1-dimethylpiperidinium iodide
| Conditions | Yield |
|---|---|
| In dichloromethane; water | 80% |
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Chemistry
Product Name: Carbocaine hydrochloride (CAS NO.1722-62-9)
IUPAC Name: N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride
Molecular Formula: C15H23ClN2O
Molecular Weight: 282.8089 g/mol
Mol File: 1722-62-9.mol
Appearance: White or off white crystalline powder
Boiling point: 383.1 °C at 760 mmHg
Flash Point: 185.5 °C
Enthalpy of Vaporization: 63.16 kJ/mol
Vapour Pressure: 4.52E-06 mmHg at 25°C
H-Bond Donor: 2
H-Bond Acceptor:2
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intravenous | 20mg/kg (20mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960. | |
| guinea pig | LD50 | subcutaneous | 94mg/kg (94mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960. | |
| mouse | LD50 | implant | 260mg/kg (260mg/kg) | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969. | |
| mouse | LD50 | intraperitoneal | 117mg/kg (117mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 40, Pg. 592, 1988. | |
| mouse | LD50 | intravenous | 32mg/kg (32mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960. | |
| mouse | LD50 | subcutaneous | 260mg/kg (260mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960. | |
| rabbit | LD50 | implant | 110mg/kg (110mg/kg) | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969. | |
| rabbit | LD50 | intravenous | 22mg/kg (22mg/kg) | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 69, 1969. | |
| rabbit | LD50 | subcutaneous | 110mg/kg (110mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 295, 1960. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by subcutaneous, intravenous, subcutaneous, and implant routes. Experimental reproductive effects. An anesthetic. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Safety Information of Carbocaine hydrochloride (CAS NO.1722-62-9):
Hazard Codes: Xn.gif){kind=small}
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 22-24/25
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes
Specification
Carbocaine hydrochloride ,its CAS NO. is 1722-62-9,the synonyms is (+-)-1-Methyl-2',6'-pipecoloxylidide monohydrochloride ; (1-Methyl-DL-piperidine-2-carboxylic acid)-2,6-dimethylanilide hydrochloride ; 1-Methyl-2',6'-pipecoloxylidide hydrochloride ; 1-Methyl-2',6'-pipecoloxylidide monohydrochloride ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride, (+-)- ; Arestocaine hydrochloride ; Carbocain ; Carbocaina ; Carbocaine ; Isocaine hydrochloride ; Meaverin ; Mepivacaine HCl ; Mepivacaine hydrochloride ; Mepivastesin ; Polocaine ; Polocaine-MPF ; Sabol ; Scandicain ; Scandicaine ; Scandinibsa ; Scandonest ; Scandonest Plain ; 2',6'-Pipecoloxylidide, 1-methyl -, monohydrochloride ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, hydrochloride (1:1) ; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride .