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17730-82-4

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Basic Information
CAS No.: 17730-82-4
Name: BUCINPERAZINE
Molecular Structure:
Molecular Structure of 17730-82-4 (BUCINPERAZINE)
Formula: C17H24 N2 O . Cl H
Molecular Weight: 308.89
Synonyms: Piperazine,1-(1-oxobutyl)-4-(3-phenyl-2-propenyl)-, monohydrochloride (9CI); Piperazine,1-butyryl-4-cinnamyl-, monohydrochloride (8CI); 1-Butyryl-4-cinnamylpiperazinehydrochloride; 1-Cinnamyl-4-butyroylpiperazine hydrochloride;1-n-Butyryl-4-cinnamylpiperazine hydrochloride; AP 237; Bucinnazinehydrochloride; Bucinperazine hydrochloride
Density: g/cm3
Boiling Point: 444.9°Cat760mmHg
Flash Point: 192.1°C
Safety: Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also ALLYL COMPOUNDS.
PSA: 23.55000
LogP: 3.32190
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Toxicity Data With Reference

1.   

orl-rat LD50:545 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 213 (1975),28.
2.   

scu-rat LD50:339 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 20 (1970),287.
3.   

ivn-rat LD50:70 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 20 (1970),287.
4.   

orl-mus LD50:710 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 213 (1975),28.
5.   

scu-mus LD50:258 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 213 (1975),28.
6.   

ivn-mus LD50:80,800 µg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 6 (1972),173.
7.   

orl-dog LDLo:260 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 25 (1973),443.
8.   

orl-gpg LD50:700 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 20 (1970),287.
9.   

scu-gpg LDLo:400 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 25 (1973),443.

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also ALLYL COMPOUNDS.