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1786-81-8

Basic Information
CAS No.: 1786-81-8
Name: Propitocaine hydrochloride
Molecular Structure:
Molecular Structure of 1786-81-8 (Propitocaine hydrochloride)
Formula: C13H20N2O.HCl
Molecular Weight: 256.77
Synonyms: Citanest hydrochloride;L 67;L 67hydrochloride;Prilocaine chloride;Propitocainehydrochloride;Xylonest;a-(Propylamino)-2-methylpropionanilide hydrochloride;Prilocaine HCL;Propanamide,N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride (9CI);o-Propionotoluidide,2-(propylamino)-, monohydrochloride (8CI);2-(Propylamino)-o-propionotoluididehydrochloride;Citanest Plain;
EINECS: 217-244-0
Density:
Melting Point: 168-170oC
Boiling Point: 361.6 °C at 760 mmHg
Flash Point: 134.3 °C
Solubility:
Appearance: White or off white crystalline powder
Hazard Symbols:
Risk Codes:
Safety:
Transport Information:
PSA: 41.13000
LogP: 3.58750
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    Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food ad

  •  Xi'an ZB Biotech Co., Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18591943808

    Address:Bldg. 3, East Of South Tangyan Road, High-Tech Zone, Xi'an, Shaanxi, China (Mainland)

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  • Propitocaine hydrochloride

  • Casno:

    1786-81-8

    Propitocaine hydrochloride

    Min.Order: 0

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    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

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Chemistry

Molecular Structure of CITANEST HYDROCHLORIDE(1786-81-8):

IUPAC Name: N-(2-methylphenyl)-2-(propylamino)propanamide hydrochloride
Molecular Formula:C13H21ClN2O
Molecular Weight:256.771640 g/mol
Appearance:white or almost white crystalline powder
Flash Point:134.3 °C
Enthalpy of Vaporization:60.74 kJ/mol
Boiling Point:361.6 °C at 760 mmHg
Vapour Pressure:2.05E-05 mmHg at 25 °C
EINECS:217-244-0
Synonyms of CITANEST HYDROCHLORIDE(1786-81-8):
2-(propylamino)-o-propionotoluidide hydrochloride;2-(propylamino)-o-propionotoluididmonohydrochloride;alpha-propylamine-2-methyl-propionanilidehydrochloride;citanesthydrochloride;l-67hydrochloride;n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride;prilocainechloride;xylonest
Categories of CITANEST HYDROCHLORIDE(1786-81-8):
Active Pharmaceutical Ingredients;Sodium channel

Uses

CITANEST HYDROCHLORIDE(1786-81-8) is a local anesthetic used for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.

Toxicity Data With Reference

1.    

ipr-rat LD50:148 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
2.    

scu-rat LD50:790 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
3.    

ivn-rat LD50:56,600 µg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
4.    

ipr-mus LD50:30 mg/kg

    29ZVAB    Handbook of Analytical Toxicology ,Sunshine, I., ed.,Cleveland, OH.: Chemical Rubber Co.,1969,99.
5.    

scu-mus LD50:632 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
6.    

ivn-mus LD50:55 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.

Safety Profile

The safety information of CITANEST HYDROCHLORIDE(1786-81-8) is as follows:
RTECS:UG5775000
Poison by intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits very toxic fumes of HCl and NOx.