CAS No.1786-81-8,Propitocaine hydrochloride Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	1786-81-8
Name:	Propitocaine hydrochloride
Article Data:	1

Formula:	C₁₃H₂₀N₂O^.HCl
Molecular Weight:	256.776
Synonyms:	Citanest hydrochloride;L 67;L 67hydrochloride;Prilocaine chloride;Propitocainehydrochloride;Xylonest;a-(Propylamino)-2-methylpropionanilide hydrochloride;Prilocaine HCL;Propanamide,N-(2-methylphenyl)-2-(propylamino)-, monohydrochloride (9CI);o-Propionotoluidide,2-(propylamino)-, monohydrochloride (8CI);2-(Propylamino)-o-propionotoluididehydrochloride;Citanest Plain;
EINECS:	217-244-0
Melting Point:	168-170oC
Boiling Point:	361.6 °C at 760 mmHg
Flash Point:	134.3 °C
Appearance:	White or off white crystalline powder
PSA:	41.13000
LogP:	3.58750

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Chemistry

Molecular Structure of CITANEST HYDROCHLORIDE(1786-81-8):

IUPAC Name: N-(2-methylphenyl)-2-(propylamino)propanamide hydrochloride
Molecular Formula:C₁₃H₂₁ClN₂O
Molecular Weight:256.771640 g/mol
Appearance:white or almost white crystalline powder
Flash Point:134.3 °C
Enthalpy of Vaporization:60.74 kJ/mol
Boiling Point:361.6 °C at 760 mmHg
Vapour Pressure:2.05E-05 mmHg at 25 °C
EINECS:217-244-0
Synonyms of CITANEST HYDROCHLORIDE(1786-81-8):
2-(propylamino)-o-propionotoluidide hydrochloride;2-(propylamino)-o-propionotoluididmonohydrochloride;alpha-propylamine-2-methyl-propionanilidehydrochloride;citanesthydrochloride;l-67hydrochloride;n-(2-methylphenyl)-2-(propylamino)-propanamidmonohydrochloride;prilocainechloride;xylonest
Categories of CITANEST HYDROCHLORIDE(1786-81-8):
Active Pharmaceutical Ingredients;Sodium channel

Uses

CITANEST HYDROCHLORIDE(1786-81-8) is a local anesthetic used for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.

Toxicity Data With Reference

1.	ipr-rat LD50:148 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
2.	scu-rat LD50:790 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
3.	ivn-rat LD50:56,600 µg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
4.	ipr-mus LD50:30 mg/kg	29ZVAB Handbook of Analytical Toxicology ,Sunshine, I., ed.,Cleveland, OH.: Chemical Rubber Co.,1969,99.
5.	scu-mus LD50:632 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.
6.	ivn-mus LD50:55 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),692.

Safety Profile

The safety information of CITANEST HYDROCHLORIDE(1786-81-8) is as follows:
RTECS:UG5775000
Poison by intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits very toxic fumes of HCl and NO_x.