Products Categories
CAS No.: | 18278-34-7 |
---|---|
Name: | 4-Hydroxy-2-methoxybenzaldehyde |
Article Data: | 26 |
Molecular Structure: | |
Formula: | C8H8O3 |
Molecular Weight: | 152.15 |
Synonyms: | 4-Hydroxy-o-anisaldehyde; |
Density: | 1.231 g/cm3 |
Melting Point: | 158-161 °C |
Boiling Point: | 312.9 °C at 760 mmHg |
Flash Point: | 132.3 °C |
Solubility: | practically insoluble in water |
Appearance: | light-yellow crystalline powder |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-36-37/39-6-36/37/39-27 |
PSA: | 46.53000 |
LogP: | 1.21330 |
What can I do for you?
Get Best Price
The 4-Hydroxy-2-methoxybenzaldehyde with cas registry number of 18278-34-7 can be classified in several categories which include Aromatic Aldehydes & Derivatives (substituted); pharmacetical; Benzaldehyde; API intermediates; aldehydes; Aromatics. Both its systematic name and IUPAC name are the same which is called 4-hydroxy-2-methoxybenzaldehyde. This chemical is off-white to greenish or light brown cryst. powder which is sensitive to air.
The physical properties about this chemical are: (1)ACD/LogP: 1.59; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.58; (4)ACD/LogD (pH 7.4): 1.28; (5)ACD/BCF (pH 5.5): 9.33; (6)ACD/BCF (pH 7.4): 4.72; (7)ACD/KOC (pH 5.5): 171.51; (8)ACD/KOC (pH 7.4): 86.82; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.587; (13)Molar Refractivity: 41.56 cm3; (14)Molar Volume: 123.5 cm3; (15)Surface Tension: 47.3 dyne/cm; (16)Density: 1.231 g/cm3; (17)Flash Point: 132.3 °C; (18)Enthalpy of Vaporization: 57.6 kJ/mol; (19)Boiling Point: 312.9 °C at 760 mmHg; (20)Vapour Pressure: 0.000279 mmHg at 25°C.
Preparation of 4-Hydroxy-2-methoxybenzaldehyde: it can be made by 4-acetoxy-2-methoxy-benzaldehyde with reagents thiophenol, KF and solvent 1-methyl-pyrrolidin-2-one. The reaction will occur at temperature 100 ℃ for 60 min with 90% yield.
Uses of 4-Hydroxy-2-methoxybenzaldehyde: this chemical can react with nitromethane to produce 3-Methoxy-4-(2nitrovinyl)phenol. This reaction will need reagents ammonium acetate, acetic acid and solvent Ethanol and heating. It will last 1 hour with 56% yield.
When you are using this chemical, please be cautious about it as the following:
Wear suitable protective clothing, gloves and eye/face protection when you are using this chemical, because it is irritating to eyes, respiratory system and skin. After use it, take off immediately all contaminated clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Store it at 0°C.
You can still convert the following datas into molecular structure:
(1)SMILES: O=Cc1ccc(O)cc1OC;
(2)InChI: InChI=1/C8H8O3/c1-11-8-4-7(10)3-2-6(8)5-9/h2-5,10H,1H3;
(3)InChIKey: WBIZZNFQJPOKDK-UHFFFAOYAH