Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 1867 > 

1867-58-9

Products Categories

Basic Information
CAS No.: 1867-58-9
Name: clomethiazole ethane-1,2-disulfonate
Molecular Structure:
Molecular Structure of 1867-58-9 (clomethiazole ethane-1,2-disulfonate)
Formula: 2C6H8ClNS·C2H6O6S2
Molecular Weight: 513.51
Synonyms: 5-(2-Chloroethyl)-4-methylthiazole ethanedisulfonate (2:1);5-(2-chloroethyl)-4-methyl-1,3-thiazole; ethane-1,2-disulfonic acid;Clomethiazole ethanedisulfonate;Clomethiazole edisylate;Ethane-1,2-disulphonic acid, compound with 5-(2-chloroethyl)-4-methylthiazole (1:2);Hemithiamine;1,2-Ethanedisulfonic acid,compd. with 5-(2-chloroethyl)-4-methylthiazole (1:2);Chlormethiazole ethanedisulfonate;Chlormethiazole edisylate;Chlormethiazole ethandisulfonate;Heminevrin;Ethane-1,2-disulfonic acid - 5-(2-chloroethyl)-4-methyl-1,3-thiazole (1:2);
EINECS: 217-483-0
Density: 1.218 g/cm3
Melting Point: 124°
Boiling Point: 751 °C at 760 mmHg
Flash Point: 408 °C
PSA: 207.76000
LogP: 5.38920
Related products
Hot Products
  • Display:default sort

    New supplier

  • Pharmaceutical Grade CAS 1867-58-9 with competitive price

  • Casno:

    1867-58-9

    Pharmaceutical Grade CAS 1867-58-9 with competitive price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is （Wen Xi Pharma）, including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • Thiazole, 5-(2-chloroethyl)-4-methyl-, ethanedisulfonate (2:1)

  • Casno:

    1867-58-9

    Thiazole, 5-(2-chloroethyl)-4-methyl-, ethanedisulfonate (2:1)

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

       Inquiry Now

  • clomethiazole ethane-1,2-disulfonate

  • Casno:

    1867-58-9

    clomethiazole ethane-1,2-disulfonate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

    Shanghai fine pharma co., Ltd. is a professional enterprise with chemical reagents and fine chemical products development, development and trade. The company has a sound research a

  • Shanghai Run-Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-21-31576854/57171705 / 57171706

    Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

       Inquiry Now

  • Total:4 Page 1 of 1 1
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1867-58-9

Specification

The Thiazole, 5-(2-chloroethyl)-4-methyl-, ethanedisulfonate (2:1), with the CAS registry number 1867-58-9, is also known as 1,2-Ethanedisulfonic acid,compd. with 5-(2-chloroethyl)-4-methylthiazole (1:2). Its EINECS number is 217-483-0. This chemical's molecular formula is 2C6H8ClNS·C2H6O6S2 and molecular weight is 513.51. What's more, its systematic name is ethane-1,2-disulfonic acid - 5-(2-chloroethyl)-4-methyl-1,3-thiazole (1:2). Its classification codes are: (1)Central Nervous System Agents; (2)Central Nervous System Depressants; (3)Drug / Therapeutic Agent; (4)Human Data; (5)Hypnotics and Sedatives. It is used in therapy of delirium tremens. 

Physical properties of Thiazole, 5-(2-chloroethyl)-4-methyl-, ethanedisulfonate (2:1) are: (1)ACD/LogP: -3.69; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -8; (4)ACD/LogD (pH 7.4): -8; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 103.5 Å2; (13)Flash Point: 408 °C; (14)Enthalpy of Vaporization: 114.86 kJ/mol; (15)Boiling Point: 751 °C at 760 mmHg; (16)Vapour Pressure: 1.07E-23 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: ClCCc1scnc1C.O=S(=O)(O)CCS(=O)(=O)O.ClCCc1scnc1C
(2)Std. InChI: InChI=1S/2C6H8ClNS.C2H6O6S2/c2*1-5-6(2-3-7)9-4-8-5;3-9(4,5)1-2-10(6,7)8/h2*4H,2-3H2,1H3;1-2H2,(H,3,4,5)(H,6,7,8)
(3)Std. InChIKey: WFVBVWRCFZCWJU-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 380mg/kg (380mg/kg) BEHAVIORAL: SLEEP Farmakologiya i Toksikologiya Vol. 25, Pg. 657, 1962.
mouse LD50 intravenous 150mg/kg (150mg/kg)   Acta Pharmaceutica Suecica. Vol. 4, Pg. 269, 1967.
mouse LD50 oral 835mg/kg (835mg/kg)   Acta Pharmaceutica Suecica. Vol. 4, Pg. 269, 1967.
mouse LD50 subcutaneous 620mg/kg (620mg/kg)   Acta Pharmaceutica Suecica. Vol. 4, Pg. 269, 1967.
women TDLo intravenous 1560mg/kg/4D- (1560mg/kg) BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Intensive Care Medicine. Vol. 10, Pg. 315, 1984.