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188612-53-5

Basic Information
CAS No.: 188612-53-5
Name: 5-(Amino-1-(N-methyl Carbamoyl)
Article Data: 11
Molecular Structure:
Molecular Structure of 188612-53-5 (5-(Amino-1-(N-methyl Carbamoyl))
Formula: N/A
Molecular Weight: 183.17
Synonyms: 5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide
Density: 1.69±0.1 g/cm3(Predicted)
Melting Point: 170 °C (decomp)
Synthetic route
360-97-4

5-Aminoimidazole-4-carboxamide

6452-47-7

methylcarbamoyl chloride

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With triethylamine In acetonitrile at -5 - 20℃; for 3h; Temperature;92.6%
65906-68-5

1-methyl-3-methylcarbamoyliminomethyl urea

6719-21-7

2-Amino-2-cyanoacetamide

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With hydrogenchloride In water; acetonitrile at 20 - 25℃; for 24h; Solvent; Reagent/catalyst;90.5%
With acetic acid In methanol at 20 - 25℃; for 18h;88.04%
72-40-2

5-amino-1H-imidazole-4-carboxamide monohydrochloride

624-83-9

methyl isocyanate

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With triethylamine In dimethyl sulfoxide at 20℃;90%
With triethylamine In dimethyl sulfoxide at 25℃;85%
With triethylamine 1.) CH3CN, 25 deg C, 10 min, 2.) 25 deg C, 18 h; Yield given. Multistep reaction;
18342-66-0

2,5-dioxopyrrolidin-1-yl methylcarbamate

360-97-4

5-Aminoimidazole-4-carboxamide

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 0 - 25℃; for 17h;88%
74-89-5

methylamine

196806-10-7

5-Amino-4-carbamoyl-imidazole-1-carboxylic acid 4-nitro-phenyl ester

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
In tetrahydrofuran at 25℃; for 5h;87%
In tetrahydrofuran; ethanol at 25℃;48%
360-97-4

5-Aminoimidazole-4-carboxamide

72002-25-6

imidazole-1-carboxylic acid N-methylamide

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
In acetonitrile at 55 - 60℃; for 6h; Solvent;80%
360-97-4

5-Aminoimidazole-4-carboxamide

6452-47-7

methylcarbamoyl chloride

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With triethylamine In acetonitrile at -5 - 20℃; for 3h; Temperature;92.6%
65906-68-5

1-methyl-3-methylcarbamoyliminomethyl urea

6719-21-7

2-Amino-2-cyanoacetamide

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With hydrogenchloride In water; acetonitrile at 20 - 25℃; for 24h; Solvent; Reagent/catalyst;90.5%
With acetic acid In methanol at 20 - 25℃; for 18h;88.04%
72-40-2

5-amino-1H-imidazole-4-carboxamide monohydrochloride

624-83-9

methyl isocyanate

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With triethylamine In dimethyl sulfoxide at 20℃;90%
With triethylamine In dimethyl sulfoxide at 25℃;85%
With triethylamine 1.) CH3CN, 25 deg C, 10 min, 2.) 25 deg C, 18 h; Yield given. Multistep reaction;
18342-66-0

2,5-dioxopyrrolidin-1-yl methylcarbamate

360-97-4

5-Aminoimidazole-4-carboxamide

188612-53-5

5-amino-N1-methyl-1H-imidazole-1,4-dicarboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 0 - 25℃; for 17h;88%
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