Products Categories
| CAS No.: | 189388-22-5 |
|---|---|
| Name: | ENDOMORPHIN-1 |
| Article Data: | 9 |
| Molecular Structure: | |
|
|
|
| Formula: | C34H38N6O5 |
| Molecular Weight: | 610.713 |
| Synonyms: | L-Tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide; |
| Density: | 1.343 g/cm3 |
| Melting Point: | 144-146℃ |
| Boiling Point: | 1052.765 °C at 760 mmHg |
| Flash Point: | 590.491 °C |
| Appearance: | Solid. (Solid powder.) |
| PSA: | 183.64000 |
| LogP: | 3.79490 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 211914-50-0N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride
- 240444-70-62,3,5,6-Tetrafluor-4-(methoxymethyl)benzyl-2,2-dimethyl-3-(prop-1-en-1-yl)cyclopropancarboxylat
- Total:24 Page 1 of 1 1
What can I do for you?
Get Best Price
Chemistry
Formula :C34H38N6O5
M.W. 610.7
Solubility:soluble in water.
Chemcial structure:
Specification
Endomorphin-1 (EM-1) should be stored at -20°C. Keep container tightly closed.Endomorphin-1 (189388-22-5) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 (189388-22-5) activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2) . However, Endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor.
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2) are tetrapeptides with the highest known affinity and specificity for the μ opioid receptor.Endomorphin-1 is located in the nucleus of the solitary tract, the periventricular hypothalamus, and the dorsomedial hypothalamus, where it is found within histaminergic neurons and may regulate sedative and arousal behaviors.