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| CAS No.: | 18968-99-5 |
|---|---|
| Name: | MAGNESIUM PEMOLINE |
| Molecular Structure: | |
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| Formula: | C9H10MgN2O4 |
| Molecular Weight: | 234.52 |
| Synonyms: | (2-imino-5-phenyl-4-oxazolidinonato(2-))diaquomagnesium;2-imino-5-phenyl-4(5h)-oxazolidinonmixt.withmagnesiumhydroxide;2-imino-5-phenyl-4-oxazolidinonemagnesiumchelate;2-imino-5-phenyl-4-oxazolidinonmixt.withmagnesiumhydroxide;abbott30400;bis(aquo)-n,n’-(2-imino-5-phenyl-4-oxazolidinone)magnesium(ii);magnesiumpemolate;pemolinandmagnesiumhydroxide |
| EINECS: | 404-080-1 |
| Density: | g/cm3 |
| Melting Point: | >299.85°C |
| Boiling Point: | 313.6 °C at 760 mmHg |
| Flash Point: | 143.4 °C |
| Safety: | Poison by ingestion. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx. See also MAGNESIUM COMPOUNDS and ORGANOMETALS. |
| PSA: | 105.14000 |
| LogP: | 0.38150 |
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This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
Chemistry
MF: C9H10MgN2O4
MW: 234.49
Flash Point: 143.4 °C
Enthalpy of Vaporization: 55.46 kJ/mol
Boiling Point: 313.6 °C at 760 mmHg
Vapour Pressure of Pemoline magnesium (18968-99-5): 0.000493 mmHg at 25°C
IUPAC Name: magnesium 2-amino-5-phenyl-1,3-oxazol-4-one dihydroxide
Synonyms: (2-Imino-5-phenyl-4-oxazolidinonato(2-))diaquomagnesium ; 2-Imino-5-phenyl-4(5h)-oxazolidinonmixt.withmagnesiumhydroxide ; 2-imino-5-phenyl-4-oxazolidinonemagnesiumchelate ; 2-Imino-5-phenyl-4-oxazolidinonmixt.withmagnesiumhydroxide ; ABBOTT30400 ; Bis(aquo)-N,N’-(2-imino-5-phenyl-4-oxazolidinone)magnesium(II) ; Magnesiumpemolate ; Pemolinandmagnesiumhydroxide
Following is the molecular structure of Pemoline magnesium (18968-99-5):
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Uses
Pemoline magnesium (18968-99-5)can enhancement of Brain RNA Polymerases: The stimulation by magnesium pemoline of systems that synthesize brain nucleic acid was studied in vivo and in vitro. There are differential effects between true RNA polymerase and pseudo-RNA polymerase. The selective stimulation of true RNA polymerase by magnesium pemoline was not observed with stimulants of the central nervous system and psychotropic agents.
Toxicity Data With Reference
The toxicity of Pemoline magnesium (18968-99-5):
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| child | TDLo | oral | 149mg/kg (149mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: NAUSEA OR VOMITING | Clinical Pediatrics Vol. 18, Pg. 761, 1979. |
| monkey | LD50 | oral | 400mg/kg (400mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969. |
| mouse | LD50 | intraperitoneal | 487mg/kg (487mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969. |
| mouse | LD50 | oral | 500mg/kg (500mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: IRRITABILITY | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969. |
| rat | LD50 | oral | 485mg/kg (485mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 810, 1973. |
Safety Profile
Poison by ingestion. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.