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CAS No.: | 198821-22-6 |
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Name: | MeriMepodib, VI-21497, VX-497 |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C23H24N4O6 |
Molecular Weight: | 452.467 |
Synonyms: | MMPD;Merimepodib;Tyverb/Tykerb;Merimebodib;VX-497;Merimepodib (USAN/INN); |
Density: | 1.36g/cm3 |
Boiling Point: | 571.4°Cat760mmHg |
Flash Point: | 299.4°C |
PSA: | 130.93000 |
LogP: | 4.30030 |
3-methoxy-4-(1,3-oxazol-5-yl)aniline
VX-497
Conditions | Yield |
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With N-ethyl-N,N-diisopropylamine In ethyl acetate at 20 - 85℃; for 25h; Product distribution / selectivity; Heating / reflux; | 90.4% |
1-({[(3S)-tetrahydro-3-furanyloxy]carbonyl}oxy)-2,5-pyrrolidinedione
VX-497
Conditions | Yield |
---|---|
With triethylamine In DMF (N,N-dimethyl-formamide); dichloromethane at 0 - 20℃; | 85% |
VX-497
(S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate hydrochloride
Conditions | Yield |
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With hydrogenchloride; acetic acid In tert-butyl methyl ether; isopropyl alcohol at -20 - 20℃; Product distribution / selectivity; | |
With hydrogenchloride In water at 0 - 5℃; for 1h; |