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20265-97-8

Basic Information
CAS No.: 20265-97-8
Name: P-ANISIDINE HYDROCHLORIDE
Article Data: 25
Molecular Structure:
Molecular Structure of 20265-97-8 (P-ANISIDINE HYDROCHLORIDE)
Formula: C7H9NO•ClH
Molecular Weight: 159.615
Synonyms: 4-Methoxyaniline hydrochloride;DSSTox_CID_93;p-Anisidine Hydrochloride;4-Anisidine Hydrochloride;4-methoxyphenylaniline hydrochloride;p-anisidine HCl;p-methoxyphenylammonium chloride;Benzenamine, 4-methoxy-, hydrochloride;p-methoxyaniline hydrochloride;
Density: 1.23g/cm3
Melting Point: 216-219oC
Boiling Point: 265.9°Cat760mmHg
Flash Point: 114.6°C
Solubility: within almost transparency
Appearance: BROWN-GREY CRYSTALLINE POWDER
Hazard Symbols: T+
Risk Codes: R33; R26/27/28
Safety: Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
PSA: 35.25000
LogP: 2.66060
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Chemistry

MF: C7H10ClNO
MW: 159.61
EINECS: 243-657-0
Flash Point: 104.5 °C
Melting Point: 216-219 °C 
Enthalpy of Vaporization: 48.31 kJ/mol 
Boiling Point: 246 °C at 760 mmHg
Vapour Pressure: 0.0278 mmHg at 25°
Appearance: Brown-grey crystalline powder 
IUPAC Name: 4-Methoxyaniline hydrochloride
Air & Water Reactions: P-Aminoanisol hydrochloride may be sensitive to prolonged exposure to air and light. Insoluble in water.   
Synonyms: P-Methoxyaniline hydrochloride ; P-Aminoanisol hydrochloride ; P-anisidinium chloride ; P-anisidine HCL ; P-anisidine hydrochloride ; 1-Amino-4-methoxybenzenehydrochloride ; 4-Aminoanisolehydrochloride ; 4-Anisidinehydrochloride
Following is the molecular structure of P-Aminoanisol hydrochloride (20265-97-8):

Production

 
Reactivity Profile P-Aminoanisol hydrochloride (20265-97-8): An acidic organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Toxicity Data With Reference

1.    

mmo-sat 33 µg/plate

    ENMUDM    Environmental Mutagenesis. 7 (Suppl 5)(1985),1.
2.    

mmo-esc 1 mg/plate

    ENMUDM    Environmental Mutagenesis. 7 (Suppl 5)(1985),1.

Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 (1982),p. 63.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; NCI Carcinogenesis Bioassay (feed); No Evidence: mouse NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-116 ,1978. ; Inadequate Studies: rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-116 ,1978. . Reported in EPA TSCA Inventory.

Safety Profile

Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information P-Aminoanisol hydrochloride (20265-97-8):
Hazard Codes: T+
T+: Very Toxic 
Risk Statements: 33-26/27/28
33: Danger of cumulative effects 
26/27/28: Very Toxic by inhalation, in contact with skin and if swallowed 
Safety Statements: 45-36/37/39-28A-1
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37/39: Wear suitable protective clothing, gloves and eye/face protection  
RTECS: BZ6600000