Products Categories
| CAS No.: | 2133-40-6 |
|---|---|
| Name: | Methyl L-prolinate hydrochloride |
| Article Data: | 134 |
| Molecular Structure: | |
|
|
|
| Formula: | C6H12ClNO2 |
| Molecular Weight: | 165.62 |
| Synonyms: | L-Proline,methyl ester, hydrochloride (9CI);Proline, methyl ester, hydrochloride, L-(6CI,7CI,8CI);(2S)-(Methoxycarbonyl)pyrrolidine hydrochloride;(S)-Methylpyrrolidine-2-carboxylate hydrochloride;(S)-Pyrrolidine-2-carboxylic acid methyl ester hydrochloride;L-Proline methyl ester monohydrochloride;Methyl proline hydrochloride;H-Pro-OMe.HCl;H-Pro-OMe·HCl;L-Proline, methylester, hydrochloride (1:1); |
| EINECS: | 218-363-0 |
| Density: | 1.055 g/cm3 |
| Melting Point: | 69-71 °C(lit.) |
| Boiling Point: | 169.9 °C at 760 mmHg |
| Flash Point: | 56.5 °C |
| Appearance: | crystalline |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/38 |
| Safety: | 26-37/39 |
| PSA: | 38.33000 |
| LogP: | 1.04220 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 240444-70-62,3,5,6-Tetrafluor-4-(methoxymethyl)benzyl-2,2-dimethyl-3-(prop-1-en-1-yl)cyclopropancarboxylat
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
| Conditions | Yield |
|---|---|
| With thionyl chloride for 1.5h; Heating; | 100% |
| With hydrogenchloride for 4h; Ambient temperature; | 100% |
| With thionyl chloride for 1.5h; Heating; | 100% |
| Conditions | Yield |
|---|---|
| With thionyl chloride In methanol at 20℃; | 100% |
| With sulfuryl dichloride; trimethyl orthoformate In methanol | |
| With sulfuryl dichloride; trimethyl orthoformate In methanol | |
| With sulfuryl dichloride; trimethyl orthoformate In methanol |
| Conditions | Yield |
|---|---|
| With hydrogen; palladium on activated charcoal In ethanol; ethyl acetate at 80℃; under 750.075 Torr; | 99% |
- 59936-29-7
(S)-N-(tert-butoxycarbonyl)proline methyl ester
- 2133-40-6
L-proline methyl ester monohydrochloride
| Conditions | Yield |
|---|---|
| With aluminium chloride doped on a neutral alumina for 0.0166667h; Irradiation; | 88% |
| With thionyl chloride In methanol at 0 - 75℃; for 1.5h; | 86% |
| With hydrogenchloride In ethyl acetate at 15℃; for 2h; |
- 67-56-1
methanol
- 15761-39-4
1-(tert-butoxycarbonyl)-L-proline
- 2133-40-6
L-proline methyl ester monohydrochloride
| Conditions | Yield |
|---|---|
| Stage #1: methanol; 1-(tert-butoxycarbonyl)-L-proline With thionyl chloride at 70℃; for 7.5h; Inert atmosphere; Cooling with ice; Stage #2: With hydrogenchloride In dichloromethane; ethyl acetate at 20℃; for 0.0833333h; Inert atmosphere; | 88% |
| Stage #1: methanol; 1-(tert-butoxycarbonyl)-L-proline With thionyl chloride at 70℃; for 7.5h; Cooling with ice; Stage #2: With hydrogenchloride In dichloromethane; ethyl acetate at 20℃; for 0.0833333h; | 88% |
| Conditions | Yield |
|---|---|
| With thionyl chloride Ambient temperature; |
| Conditions | Yield |
|---|---|
| Stage #1: L-proline With thionyl chloride Stage #2: methyl iodide |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: SOCl2 View Scheme |
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water |
- 21348-59-4COLUMBIUM OXALATE
- 21351-39-3uronium hydrogen sulphate
- 213598-11-9METHYL 3-CYANO-4-ISOPROPOXYBENZOATE
- 21361-35-3BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)MAGNESIUM DIHYDRATE
- 213629-14-2Siloxanes and Silicones, di-Me, Me hydrogen, reaction products with 1,5-hexadiene
- 213690-54-1(S)-N-((S)-1-(methoxymethyl)-2-methylpropyl)-1-phenyl-3-butenylamine
- 213697-53-12-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl
- 21369-76-6α-Chloroacrylic acid chloride
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Chemistry
The Molecular Structure of L-Proline methyl ester hydrochloride (CAS NO.2133-40-6):
Empirical Formula: C6H12ClNO2
Molecular Weight: 165.618
IUPAC Name: methyl pyrrolidine-2-carboxylate hydrochloride
Appearance: Crystalline
Nominal Mass: 165 Da
Average Mass: 165.618 Da
Monoisotopic Mass: 165.055656 Da
Flash Point: 56.5 °C
Melting Point: 69-71 °C
Enthalpy of Vaporization: 40.63 kJ/mol
Boiling Point: 169.9 °C at 760 mmHg
Vapour Pressure: 1.51 mmHg at 25°C
Synonyms: H-l-pro-ome hcl ; H-pro-ome hcl ; Methyl l-prolinate hydrochloride ; L-pyrrolidine-2-carboxylic acid methyl ester hcl ; L-proline methyl ester hydrochloride ; L-proline methyl ester hydrochloride salt ; Proline-ome hcl ; L-proline methyl ester hcl
Product Categories: AMINOACIDS DERIVATIVES;Esters;Pyrrolidines;Amino Acid Derivatives;Amino Acids;Proline [Pro, P];Amino Acids and Derivatives;Amino hydrochloride;Peptide Synthesis;Amino Acid Derivatives;Proline
Toxicity Data With Reference
Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/38
R36/38: Irritating to eyes and skin
Safety Statements: 26-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
F: 3-8-10-21
Hazard Note: Harmful
Specification
Conditions to Avoid: Incompatible materials, dust generation, excess HEAT, exposure to moist air or WATER.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, NITROGEN oxides, CARBON monoxide, irritating and toxic fumes and gases, CARBON dioxide.
Hazardous Polymerization: Has not been reported